Betaine attenuates alcoholic steatosis by restoring phosphatidylcholine generation via the phosphatidylethanolamine methyltransferase pathway
about
Aberrant post-translational protein modifications in the pathogenesis of alcohol-induced liver injuryOptimal management for alcoholic liver disease: Conventional medications, natural therapy or combination?Vitamin-dependent methionine metabolism and alcoholic liver diseaseAlcoholic and non-alcoholic steatohepatitisAssociations of gut-flora-dependent metabolite trimethylamine-N-oxide, betaine and choline with non-alcoholic fatty liver disease in adults.Hepatoprotectant ursodeoxycholyl lysophosphatidylethanolamide increasing phosphatidylcholine levels as a potential therapy of acute liver injuryEthanol lowers glutathione in rat liver and brain and inhibits methionine synthase in a cobalamin-dependent mannerProteomics reveal a concerted upregulation of methionine metabolic pathway enzymes, and downregulation of carbonic anhydrase-III, in betaine supplemented ethanol-fed ratsMethyl-donor supplementation in obese mice prevents the progression of NAFLD, activates AMPK and decreases acyl-carnitine levels.The effects of choline on hepatic lipid metabolism, mitochondrial function and antioxidative status in human hepatic C3A cells exposed to excessive energy substrates.Liquid chromatography-mass spectrometry-based parallel metabolic profiling of human and mouse model serum reveals putative biomarkers associated with the progression of nonalcoholic fatty liver disease.Involvement and mechanism of DGAT2 upregulation in the pathogenesis of alcoholic fatty liver disease.Involvement of AMP-activated protein kinase in beneficial effects of betaine on high-sucrose diet-induced hepatic steatosis.Treatment of alcoholic liver disease.¹H and ³¹P NMR lipidome of ethanol-induced fatty liver.Betaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trial.Aberrant hepatic methionine metabolism and gene methylation in the pathogenesis and treatment of alcoholic steatohepatitis.Deletion of betaine-homocysteine S-methyltransferase in mice perturbs choline and 1-carbon metabolism, resulting in fatty liver and hepatocellular carcinomasMethionine adenosyltransferase 1A gene deletion disrupts hepatic very low-density lipoprotein assembly in miceBetaine treatment attenuates chronic ethanol-induced hepatic steatosis and alterations to the mitochondrial respiratory chain proteomeChronic alcohol exposure alters gene expression in HepG2 cells.Ethanol and hepatitis C virus suppress peptide-MHC class I presentation in hepatocytes by altering proteasome function.Betaine protects cerebellum from oxidative stress following levodopa and benserazide administration in ratsMitochondrial dysfunction and oxidative stress in the pathogenesis of alcohol- and obesity-induced fatty liver diseases.Dietary Betaine Supplementation Increases Fgf21 Levels to Improve Glucose Homeostasis and Reduce Hepatic Lipid Accumulation in MiceBetaine supplement alleviates hepatic triglyceride accumulation of apolipoprotein E deficient mice via reducing methylation of peroxisomal proliferator-activated receptor alpha promoter.Structure, function and metabolism of hepatic and adipose tissue lipid droplets: implications in alcoholic liver disease.Role of transmethylation reactions in alcoholic liver disease.Effect of transgenic extrahepatic expression of betaine-homocysteine methyltransferase on alcohol or homocysteine-induced fatty liver.Folate, alcohol, and liver disease.Mechanisms of protection by the betaine-homocysteine methyltransferase/betaine system in HepG2 cells and primary mouse hepatocytes.Epigenetics of proteasome inhibition in the liver of rats fed ethanol chronicallyThe methyl donor S-adenosylmethionine prevents liver hypoxia and dysregulation of mitochondrial bioenergetic function in a rat model of alcohol-induced fatty liver disease.New concepts in the pathogenesis of alcoholic liver disease.Dietary fat sources differentially modulate intestinal barrier and hepatic inflammation in alcohol-induced liver injury in ratsQuantitative lipid metabolomic changes in alcoholic micropigs with fatty liver disease.Rab GTPases associate with isolated lipid droplets (LDs) and show altered content after ethanol administration: potential role in alcohol-impaired LD metabolism.Choline and betaine in health and disease.Choline deprivation: an overview of the major hepatic metabolic response pathways.Natural products from marine organisms with neuroprotective activity in the experimental models of Alzheimer's disease, Parkinson's disease and ischemic brain stroke: their molecular targets and action mechanisms.
P2860
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P2860
Betaine attenuates alcoholic steatosis by restoring phosphatidylcholine generation via the phosphatidylethanolamine methyltransferase pathway
description
2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im Februar 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/02/01)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/02/01)
@nl
наукова стаття, опублікована в лютому 2007
@uk
مقالة علمية (نشرت في فبراير 2007)
@ar
name
Betaine attenuates alcoholic s ...... mine methyltransferase pathway
@ast
Betaine attenuates alcoholic s ...... mine methyltransferase pathway
@en
Betaine attenuates alcoholic s ...... mine methyltransferase pathway
@nl
type
label
Betaine attenuates alcoholic s ...... mine methyltransferase pathway
@ast
Betaine attenuates alcoholic s ...... mine methyltransferase pathway
@en
Betaine attenuates alcoholic s ...... mine methyltransferase pathway
@nl
prefLabel
Betaine attenuates alcoholic s ...... mine methyltransferase pathway
@ast
Betaine attenuates alcoholic s ...... mine methyltransferase pathway
@en
Betaine attenuates alcoholic s ...... mine methyltransferase pathway
@nl
P2093
P3181
P1476
Betaine attenuates alcoholic s ...... mine methyltransferase pathway
@en
P2093
Cheryl R. Baldwin
Dean J. Tuma
Harriet C. Beckenhauer
Kusum K. Kharbanda
Mark E. Mailliard
Michael F. Sorrell
P304
P3181
P356
10.1016/J.JHEP.2006.08.024
P577
2007-02-01T00:00:00Z