Myostatin short interfering hairpin RNA gene transfer increases skeletal muscle mass
about
Pharmacology of manipulating lean body massGene doping: gene delivery for olympic victoryTwo novel missense mutations in the myostatin gene identified in Japanese patients with Duchenne muscular dystrophy.Myostatin is upregulated following stress in an Erk-dependent manner and negatively regulates cardiomyocyte growth in culture and in a mouse model.Dual exon skipping in myostatin and dystrophin for Duchenne muscular dystrophy.Combination of myostatin pathway interference and dystrophin rescue enhances tetanic and specific force in dystrophic mdx miceMicroRNA-mediated myostatin silencing in caprine fetal fibroblastsSingle muscle fiber gene expression with run taper.Local applications of myostatin-siRNA with atelocollagen increase skeletal muscle mass and recovery of muscle functionTargeting the activin type IIB receptor to improve muscle mass and function in the mdx mouse model of Duchenne muscular dystrophy.Production of transgenic calves expressing an shRNA targeting myostatin.TGF-b superfamily cytokine MIC-1/GDF15 is a physiological appetite and body weight regulatorMyostatin genetic inactivation inhibits myogenesis by muscle-derived stem cells in vitro but not when implanted in the mdx mouse muscle.Fundamental study of detection of muscle hypertrophy-oriented gene doping by myostatin knock down using RNA interference.AAV vectors for RNA-based modulation of gene expression.Coordinated patterns of gene expressions for adult muscle build-up in transgenic mice expressing myostatin propeptide.Relation between extent of myostatin depletion and muscle growth in mature mice.A high-content, high-throughput siRNA screen identifies cyclin D2 as a potent regulator of muscle progenitor cell fusion and a target to enhance muscle regeneration.Gene therapy for muscular dystrophy: current progress and future prospects.Muscle Derived Stem Cells Stimulate Muscle Myofiber Repair and Counteract Fat Infiltration in a Diabetic Mouse Model of Critical Limb Ischemia.Local overexpression of the myostatin propeptide increases glucose transporter expression and enhances skeletal muscle glucose disposal.Combinatory effects of siRNA-induced myostatin inhibition and exercise on skeletal muscle homeostasis and body composition.Myostatin and the skeletal muscle atrophy and hypertrophy signaling pathways.In vitro silencing of myostatin gene by shRNAs in chicken embryonic myoblast cells.Gene electrotransfer: from biophysical mechanisms to in vivo applications : Part 2 - In vivo developments and present clinical applications.Pharmacological therapeutics targeting the secondary defects and downstream pathology of Duchenne muscular dystrophySelection of an effective small interference RNA to silence myostatin gene expression in sheep fibroblast cells.Atelocollagen-mediated local and systemic applications of myostatin-targeting siRNA increase skeletal muscle mass.Small RNA-Mediated Epigenetic Myostatin Silencing.Targeted ablation of beta cells in the embryonic zebrafish pancreas using E. coli nitroreductase.Knockdown of endogenous myostatin promotes sheep myoblast proliferation.Short hairpin RNA-induced myostatin gene silencing in caprine myoblast cells in vitro.Optimizing hyaluronidase dose and plasmid DNA delivery greatly improves gene electrotransfer efficiency in rat skeletal muscle.Myostatin, a profibrotic factor and the main inhibitor of striated muscle mass, is present in the penile and vascular smooth muscle.Inhibition of myostatin gene expression in skeletal muscle of fish by in vivo electrically mediated dsRNA and shRNAi delivery.Evaluation of interferon response induced by anti-myostatin shRNA constructs in goat (Capra hircus) fetal fibroblasts by quantitative real time-polymerase chain reaction.
P2860
Q26824503-30487DA4-CDF7-4403-88F7-917EB4BF2267Q26995443-8F08B2D4-BA42-4181-BE1B-B3C866666FEBQ33281832-88F92EEE-116B-4545-819B-7509822CB808Q33564220-6E1A5B61-3109-4488-BB59-452B52260238Q33877924-E355F989-3DCB-4429-A8FD-4F9B133CC229Q33931629-C1CFEE14-EAB3-4E9E-8B87-24E82256EFD4Q34224360-5B27920A-6D04-4F10-AA55-E4FDECF75FF7Q34277356-817954A4-B9E2-4A2A-8BD0-49F6A6B12292Q34746296-FC837686-6200-4AAD-8A19-5F80B69BC5CEQ34756106-347B9DA6-F483-4C51-B3C0-66C8AD267C4EQ35785336-DF012BB9-CCEA-436A-9FF5-8F6E41CDD0D5Q36647686-1B189830-D6A6-4BCF-891F-C07B8998CDC7Q36998190-9F676C16-D52C-4254-BCA2-03852CF0D61BQ37081256-27197119-3DFE-485E-A4FF-014BAA71572AQ37140645-83D5D845-D28C-4D84-B319-FCDC93D523BBQ37270488-963E35A2-5291-4282-85F2-07AE0DD9DE5FQ37391771-013269D4-7BD8-416B-AD55-D944CFC3655EQ37464145-08A85FDA-D5C3-4193-8134-ED95A0AD19E4Q37519650-7A7CAE58-6069-48A9-BF7A-6B50D884F974Q37646812-1E3420E7-BB1F-42A1-88CE-AC0E59B3DE3EQ37656012-9731E705-30E2-4272-9033-00DD069F19EBQ37727898-046FCC76-BF7A-404C-8067-CEB97C9D2DF5Q38235659-EC55ACF4-CFFB-4651-B757-A6C791D65711Q39215581-3FEEB746-7C15-41F8-80D8-0F3AC3D602F0Q39310355-41D9990D-D645-4466-96A8-66F42F9D15D5Q39410461-FD9B287F-13CC-478D-B9A6-B229C83AF4D9Q39596457-9A360E71-9E77-45DC-B724-E49A084680E8Q40116203-EE490DED-6074-4613-A966-B7FBB16E3F0AQ41840699-F3F78A93-6AA9-4973-AB1F-025DA52BFE35Q41853648-84984D3F-B2DB-41A2-8CD4-AD0F64662AA0Q44591585-E0676E5A-D9EB-44E5-A4A0-42862BDA28D4Q46156486-A81CD14A-D9C5-44E1-B7DA-A9C8F3E086C6Q46651262-B51564BA-ABDD-478C-989E-F5259C64D4C7Q50983091-37DBC747-0223-4B83-8663-588FEA39B887Q52630733-E5E98828-0DB8-4FA9-8AD2-97301DD18FC7Q54492351-2D8B83CF-94C4-462D-90F8-AE5862312234
P2860
Myostatin short interfering hairpin RNA gene transfer increases skeletal muscle mass
description
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im September 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/09/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/09/01)
@nl
наукова стаття, опублікована у вересні 2006
@uk
مقالة علمية (نشرت في سبتمبر 2006)
@ar
name
Myostatin short interfering hairpin RNA gene transfer increases skeletal muscle mass
@ast
Myostatin short interfering hairpin RNA gene transfer increases skeletal muscle mass
@en
Myostatin short interfering hairpin RNA gene transfer increases skeletal muscle mass
@nl
type
label
Myostatin short interfering hairpin RNA gene transfer increases skeletal muscle mass
@ast
Myostatin short interfering hairpin RNA gene transfer increases skeletal muscle mass
@en
Myostatin short interfering hairpin RNA gene transfer increases skeletal muscle mass
@nl
prefLabel
Myostatin short interfering hairpin RNA gene transfer increases skeletal muscle mass
@ast
Myostatin short interfering hairpin RNA gene transfer increases skeletal muscle mass
@en
Myostatin short interfering hairpin RNA gene transfer increases skeletal muscle mass
@nl
P2093
P356
P1476
Myostatin short interfering hairpin RNA gene transfer increases skeletal muscle mass
@en
P2093
Dolores Vernet
Freddi I. Zuniga
Jacob Rajfer
Jorge N. Artaza
Liliana Cantini
Monica G. Ferrini
Nestor F. Gonzalez-Cadavid
Suzanne Reisz-Porszasz
Thomas R. Magee
P304
P356
10.1002/JGM.946
P577
2006-09-01T00:00:00Z