The c-Cbl/CD2AP complex regulates VEGF-induced endocytosis and degradation of Flt-1 (VEGFR-1)
about
Structural characterization of a novel Cbl phosphotyrosine recognition motif in the APS family of adapter proteinsCIN85 regulates dopamine receptor endocytosis and governs behaviour in miceThe cellular response to vascular endothelial growth factors requires co-ordinated signal transduction, trafficking and proteolysisDifferential Recognition Preferences of the Three Src Homology 3 (SH3) Domains from the Adaptor CD2-associated Protein (CD2AP) and Direct Association with Ras and Rab Interactor 3 (RIN3).Structure of the kidney slit diaphragm adapter protein CD2-associated protein as determined with electron microscopy.CD2-associated protein (CD2AP) enhances casitas B lineage lymphoma-3/c (Cbl-3/c)-mediated Ret isoform-specific ubiquitination and degradation via its amino-terminal Src homology 3 domains.Early endosomes associated with dynamic F-actin structures are required for late trafficking of H. pylori VacA toxin.Development and validation of a method for profiling post-translational modification activities using protein microarrays.Dynamic alterations in decoy VEGF receptor-1 stability regulate angiogenesis.Molecular genetic analysis of podocyte genes in focal segmental glomerulosclerosis--a review.CD2AP/SHIP1 complex positively regulates plasmacytoid dendritic cell receptor signaling by inhibiting the E3 ubiquitin ligase CblTranscriptional activation of the human CD2AP promoter by E2F1.Expression of novel Alzheimer's disease risk genes in control and Alzheimer's disease brains.N-terminal cleavage and release of the ectodomain of Flt1 is mediated via ADAM10 and ADAM 17 and regulated by VEGFR2 and the Flt1 intracellular domainCD2AP regulates SUMOylation of CIN85 in podocytes.Cargo- and compartment-selective endocytic scaffold proteins.Ligand-induced internalization selects use of common receptor neuropilin-1 by VEGF165 and semaphorin3AComputational investigation of sphingosine kinase 1 (SphK1) and calcium dependent ERK1/2 activation downstream of VEGFR2 in endothelial cells.c-Cbl, a ubiquitin E3 ligase that targets active β-catenin: a novel layer of Wnt signaling regulation.The Adaptor Protein CD2AP Is a Coordinator of Neurotrophin Signaling-Mediated Axon Arbor Plasticity.Neuropilin-1-VEGFR-2 complexing requires the PDZ-binding domain of neuropilin-1.CD2AP and Cbl-3/Cbl-c constitute a critical checkpoint in the regulation of ret signal transduction.VEGFR-1 regulates adult olfactory bulb neurogenesis and migration of neural progenitors in the rostral migratory stream in vivo.Regulation of VEGF signaling by membrane traffic.Endothelial CD2AP Binds the Receptor ICAM-1 To Control Mechanosignaling, Leukocyte Adhesion, and the Route of Leukocyte Diapedesis In Vitro.Ligand-independent activation of vascular endothelial growth factor receptor 1 by low-density lipoprotein.Direct binding of Cbl to Tyr568 and Tyr936 of the stem cell factor receptor/c-Kit is required for ligand-induced ubiquitination, internalization and degradation.Quantification and cell-to-cell variation of vascular endothelial growth factor receptors.Interactions between Drosophila IgCAM adhesion receptors and cindr, the Cd2ap/Cin85 orthologEndocytosis and cancer.Association of CD2AP with dynamic actin on vesicles in podocytes.Receptor Tyrosine Kinase Ubiquitination and De-Ubiquitination in Signal Transduction and Receptor Trafficking.Using High-Throughput Animal or Cell-Based Models to Functionally Characterize GWAS SignalsGenetics of Alzheimer's disease
P2860
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P2860
The c-Cbl/CD2AP complex regulates VEGF-induced endocytosis and degradation of Flt-1 (VEGFR-1)
description
2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Mai 2004 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2004/05/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/05/01)
@nl
наукова стаття, опублікована в травні 2004
@uk
مقالة علمية (نشرت في مايو 2004)
@ar
name
The c-Cbl/CD2AP complex regula ...... degradation of Flt-1 (VEGFR-1)
@ast
The c-Cbl/CD2AP complex regula ...... degradation of Flt-1 (VEGFR-1)
@en
The c-Cbl/CD2AP complex regula ...... degradation of Flt-1 (VEGFR-1)
@nl
type
label
The c-Cbl/CD2AP complex regula ...... degradation of Flt-1 (VEGFR-1)
@ast
The c-Cbl/CD2AP complex regula ...... degradation of Flt-1 (VEGFR-1)
@en
The c-Cbl/CD2AP complex regula ...... degradation of Flt-1 (VEGFR-1)
@nl
prefLabel
The c-Cbl/CD2AP complex regula ...... degradation of Flt-1 (VEGFR-1)
@ast
The c-Cbl/CD2AP complex regula ...... degradation of Flt-1 (VEGFR-1)
@en
The c-Cbl/CD2AP complex regula ...... degradation of Flt-1 (VEGFR-1)
@nl
P2093
P356
P1433
P1476
The c-Cbl/CD2AP complex regula ...... degradation of Flt-1 (VEGFR-1)
@en
P2093
Asako Sawano
Masabumi Shibuya
Satsuki Kobayashi
Yoshihisa Nojima
Yoshiro Maru
P304
P356
10.1096/FJ.03-0767FJE
P407
P577
2004-05-01T00:00:00Z