Cathepsin L participates in the production of neuropeptide Y in secretory vesicles, demonstrated by protease gene knockout and expression
about
Identification of a broad-spectrum antiviral small molecule against severe acute respiratory syndrome coronavirus and Ebola, Hendra, and Nipah viruses by using a novel high-throughput screening assayCarboxypeptidase E modulates intestinal immune homeostasis and protects against experimental colitis in miceCathepsin L colocalizes with chromogranin a in chromaffin vesicles to generate active peptidesProteolytic fragments of chromogranins A and B represent major soluble components of chromaffin granules, illustrated by two-dimensional proteomics with NH(2)-terminal Edman peptide sequencing and MALDI-TOF MSNeuropeptidomic components generated by proteomic functions in secretory vesicles for cell-cell communicationProteomics of dense core secretory vesicles reveal distinct protein categories for secretion of neuroeffectors for cell-cell communication.Enhanced neuropeptide Y synthesis during intermittent hypoxia in the rat adrenal medulla: role of reactive oxygen species-dependent alterations in precursor peptide processingUnique biological function of cathepsin L in secretory vesicles for biosynthesis of neuropeptides.Cysteine Cathepsins in the secretory vesicle produce active peptides: Cathepsin L generates peptide neurotransmitters and cathepsin B produces beta-amyloid of Alzheimer's diseaseHuman cathepsin V protease participates in production of enkephalin and NPY neuropeptide neurotransmitters.Genes and environment: novel, functional polymorphism in the human cathepsin L (CTSL1) promoter disrupts a xenobiotic response element (XRE) to alter transcription and blood pressure.Spinal astrocytes produce and secrete dynorphin neuropeptides.Cathepsin L plays a major role in cholecystokinin production in mouse brain cortex and in pituitary AtT-20 cells: protease gene knockout and inhibitor studies.The marine cyanobacterial metabolite gallinamide A is a potent and selective inhibitor of human cathepsin L.Autophagy and cathepsin L are involved in the antinociceptive effect of DMBC in a mouse acetic acid-writhing modelCysteine cathepsins in neurological disorders.The lysosomal protein cathepsin L is a progranulin protease.Neuropeptidomic analysis establishes a major role for prohormone convertase-2 in neuropeptide biosynthesis.Cathepsin B, cathepsin L, and cystatin C in the porcine uterus and placenta: potential roles in endometrial/placental remodeling and in fluid-phase transport of proteins secreted by uterine epithelia across placental areolae.Extracellular cathepsin L stimulates axonal growth in neurons.Human brain gene expression profiles of the cathepsin V and cathepsin L cysteine proteases, with the PC1/3 and PC2 serine proteases, involved in neuropeptide production.
P2860
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P2860
Cathepsin L participates in the production of neuropeptide Y in secretory vesicles, demonstrated by protease gene knockout and expression
description
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
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scientific journal article
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vedecký článok (publikovaný 2008/07/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/07/01)
@nl
наукова стаття, опублікована в липні 2008
@uk
مقالة علمية (نشرت في يوليو 2008)
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Cathepsin L participates in th ...... e gene knockout and expression
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Cathepsin L participates in th ...... e gene knockout and expression
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Cathepsin L participates in th ...... e gene knockout and expression
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type
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Cathepsin L participates in th ...... e gene knockout and expression
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Cathepsin L participates in th ...... e gene knockout and expression
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Cathepsin L participates in th ...... e gene knockout and expression
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prefLabel
Cathepsin L participates in th ...... e gene knockout and expression
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Cathepsin L participates in th ...... e gene knockout and expression
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Cathepsin L participates in th ...... e gene knockout and expression
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P2093
P2860
P1476
Cathepsin L participates in th ...... e gene knockout and expression
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P2093
Christoph Peters
Lydiane Funkelstein
Shin-Rong Hwang
Thomas Toneff
Vivian Hook
P2860
P304
P356
10.1111/J.1471-4159.2008.05408.X
P407
P577
2008-07-01T00:00:00Z