Antibody to beta3 integrin inhibits osteoclast-mediated bone resorption in the thyroparathyroidectomized rat
about
3BP2-deficient mice are osteoporotic with impaired osteoblast and osteoclast functionsDisease-modifying activity of SB 273005, an orally active, nonpeptide alphavbeta3 (vitronectin receptor) antagonist, in rat adjuvant-induced arthritis.Current and potential future drug treatments for osteoporosis.Beta3-integrin-deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival.Integrins and bone metastasis: integrating tumor cell and stromal cell interactions.Integrin targeted therapeutics.The type II collagen N-propeptide, PIIBNP, inhibits cell survival and bone resorption of osteoclasts via integrin-mediated signaling.Macrophage and retinal pigment epithelium phagocytosis: apoptotic cells and photoreceptors compete for alphavbeta3 and alphavbeta5 integrins, and protein kinase C regulates alphavbeta5 binding and cytoskeletal linkage.Osteopontin-deficient mice are resistant to ovariectomy-induced bone resorption.Noninvasive imaging of osteoclasts in parathyroid hormone-induced osteolysis using a 64Cu-labeled RGD peptide.A peptidomimetic antagonist of the alpha(v)beta3 integrin inhibits bone resorption in vitro and prevents osteoporosis in vivo.Regulation of osteoclast function.The blocking of uPAR suppresses lipopolysaccharide-induced inflammatory osteoclastogenesis and the resultant bone loss through attenuation of integrin β3/Akt pathway
P2860
Q30010273-E47ED0FB-550D-4300-BB31-B48080135B8AQ32044975-37DEA2BD-F57D-49C2-9DC7-90EB5A01F17AQ33579316-0F65E7C0-10B9-4509-9C32-B95A897310F6Q33835366-E8E5EE70-FA01-45A9-9928-8C6CCACCFEFFQ34441622-F156C926-3EB0-4001-A805-02825CCDBF08Q34912684-8DCA9063-2A44-4CDC-A816-AE6B8D9EA793Q35196305-047F2E9F-9985-4200-BE0B-E412E2D23E1CQ36375325-30814531-6E7F-4368-9178-A88B5920DD14Q36417911-BBFDB7C8-F8F5-4763-815E-A7D46E6448F0Q37263864-E92D2155-F521-412A-BCA9-7138B73DFB96Q37366963-500C74AD-E2FF-4507-8708-FACB7F2EAC23Q37939688-D11598FB-09B3-4BF9-AB60-C6E5208A360EQ40972086-E05B4907-7762-4E02-A85F-F7B8C21AF2AE
P2860
Antibody to beta3 integrin inhibits osteoclast-mediated bone resorption in the thyroparathyroidectomized rat
description
1996 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1996
@ast
im März 1996 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1996/03/01)
@sk
vědecký článek publikovaný v roce 1996
@cs
wetenschappelijk artikel (gepubliceerd op 1996/03/01)
@nl
наукова стаття, опублікована в березні 1996
@uk
مقالة علمية (نشرت في مارس 1996)
@ar
name
Antibody to beta3 integrin inh ...... thyroparathyroidectomized rat
@ast
Antibody to beta3 integrin inh ...... thyroparathyroidectomized rat
@en
Antibody to beta3 integrin inh ...... thyroparathyroidectomized rat
@nl
type
label
Antibody to beta3 integrin inh ...... thyroparathyroidectomized rat
@ast
Antibody to beta3 integrin inh ...... thyroparathyroidectomized rat
@en
Antibody to beta3 integrin inh ...... thyroparathyroidectomized rat
@nl
prefLabel
Antibody to beta3 integrin inh ...... thyroparathyroidectomized rat
@ast
Antibody to beta3 integrin inh ...... thyroparathyroidectomized rat
@en
Antibody to beta3 integrin inh ...... thyroparathyroidectomized rat
@nl
P2093
P3181
P1433
P1476
Antibody to beta3 integrin inh ...... thyroparathyroidectomized rat
@en
P2093
B. A. Crippes
G. A. Nickols
J. Delarco
M. A. Horton
M. H. Helfrich
R. L. Ornberg
S. L. Settle
V. W. Engleman
P304
P3181
P356
10.1210/ENDO.137.3.8603604
P407
P577
1996-03-01T00:00:00Z