A splice variant of CD44 expressed in the apical ectodermal ridge presents fibroblast growth factors to limb mesenchyme and is required for limb outgrowth
about
ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicingRegulation of CD44 alternative splicing by SRm160 and its potential role in tumor cell invasionHigh throughput SNP and expression analyses of candidate genes for non-syndromic oral cleftsCD44 in rheumatoid arthritisThe Role of Alternative Splicing in the Control of Immune Homeostasis and Cellular DifferentiationAnisotropic stress orients remodelling of mammalian limb bud ectoderm.Structural Basis for Homodimerization of the Src-associated during Mitosis, 68-kDa Protein (Sam68) Qua1 DomainCD44, Hyaluronan, the Hematopoietic Stem Cell, and Leukemia-Initiating CellsThe NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44Hepatocyte growth factor-induced Ras activation requires ERM proteins linked to both CD44v6 and F-actinConservation of CD44 exon v3 functional elements in mammalsCD44v6 coordinates tumor matrix-triggered motility and apoptosis resistance.Resolving deconvolution ambiguity in gene alternative splicing.Activation of Ras requires the ERM-dependent link of actin to the plasma membrane.Extracellular matrix degradation and remodeling in development and diseaseBmp2, Bmp4 and Bmp7 are co-required in the mouse AER for normal digit patterning but not limb outgrowth.Impact of constitutional polymorphisms in VCAM1 and CD44 on CD34+ cell collection yield after administration of granulocyte colony-stimulating factor to healthy donors.Regulation of alternative pre-mRNA splicing by the ERK MAP-kinase pathwayA positive feedback loop couples Ras activation and CD44 alternative splicingA mutation in a CD44 variant of inflammatory cells enhances the mitogenic interaction of FGF with its receptor.CD44 anchors the assembly of matrilysin/MMP-7 with heparin-binding epidermal growth factor precursor and ErbB4 and regulates female reproductive organ remodelingArrested oligodendrocyte lineage maturation in chronic perinatal white matter injury.Localization of matrix metalloproteinase 9 to the cell surface provides a mechanism for CD44-mediated tumor invasion.CD44 is required for two consecutive steps in HGF/c-Met signaling.Expression of c-Met and heparan-sulfate proteoglycan forms of CD44 in colorectal cancerNGF-induced TrkA/CD44 association is involved in tumor aggressiveness and resistance to lestaurtinib.The effect of anti-CD44 monoclonal antibodies on differentiation and proliferation of human acute myeloid leukemia cells.Distinct Intracellular Domain Substrate Modifications Selectively Regulate Ectodomain Cleavage of NRG1 or CD44.Isolation of All CD44 Transcripts in Human Epidermis and Regulation of Their Expression by Various Agents.CD44 enhances neuregulin signaling by Schwann cells.CD44 interacts with EGFR and promotes head and neck squamous cell carcinoma initiation and progression.Syndactyly in a novel Fras1(rdf) mutant results from interruption of signals for interdigital apoptosis.The apical ectodermal ridge is a timer for generating distal limb progenitors.Dosage-dependent hedgehog signals integrated with Wnt/beta-catenin signaling regulate external genitalia formation as an appendicular program.Epidermal-specific deletion of CD44 reveals a function in keratinocytes in response to mechanical stress.CD44 in hematological neoplasias.Complex changes in alternative pre-mRNA splicing play a central role in the epithelial-to-mesenchymal transition (EMT).CD44 integrates signaling in normal stem cell, cancer stem cell and (pre)metastatic niches.Butyrate down-regulates CD44 transcription and liver colonisation in a highly metastatic human colon carcinoma cell line.CD44 mediates the catch-bond activated rolling of HEPG2Iso epithelial cancer cells on hyaluronan.
P2860
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P2860
A splice variant of CD44 expressed in the apical ectodermal ridge presents fibroblast growth factors to limb mesenchyme and is required for limb outgrowth
description
1998 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1998
@ast
im April 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998/04/01)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/04/01)
@nl
наукова стаття, опублікована у квітні 1998
@uk
مقالة علمية (نشرت في أبريل 1998)
@ar
name
A splice variant of CD44 expre ...... is required for limb outgrowth
@ast
A splice variant of CD44 expre ...... is required for limb outgrowth
@en
A splice variant of CD44 expre ...... is required for limb outgrowth
@nl
type
label
A splice variant of CD44 expre ...... is required for limb outgrowth
@ast
A splice variant of CD44 expre ...... is required for limb outgrowth
@en
A splice variant of CD44 expre ...... is required for limb outgrowth
@nl
prefLabel
A splice variant of CD44 expre ...... is required for limb outgrowth
@ast
A splice variant of CD44 expre ...... is required for limb outgrowth
@en
A splice variant of CD44 expre ...... is required for limb outgrowth
@nl
P2093
P2860
P3181
P356
P1433
P1476
A splice variant of CD44 expre ...... is required for limb outgrowth
@en
P2093
D. Wainwright
L. Sherman
P. Herrlich
P2860
P304
P3181
P356
10.1101/GAD.12.7.1058
P577
1998-04-01T00:00:00Z