An intramembrane modulator of the ErbB2 receptor tyrosine kinase that potentiates neuregulin signaling
about
Relationship between novel isoforms, functionally important domains, and subcellular distribution of CD164/endolynMuc13, a novel human cell surface mucin expressed by epithelial and hemopoietic cellsMUC1 and MUC4: switching the emphasis from large to smallMUC4 mucin interacts with and stabilizes the HER2 oncoprotein in human pancreatic cancer cellsStructure, evolution, and biology of the MUC4 mucinMucins in cancer: function, prognosis and therapyThe membrane mucin MUC4 is elevated in breast tumor lymph node metastases relative to matched primary tumors and confers aggressive properties to breast cancer cellsClinicopathological and prognostic significance of MUC4 expression in cancers: evidence from meta-analysisThe ErbB4 receptor in fetal rat lung fibroblasts and epithelial type II cellsExtracellular regulated kinase (ERK)-dependent regulation of sialomucin complex/rat Muc4 in mammary epithelial cellsThe membrane mucin Muc4 inhibits apoptosis induced by multiple insults via ErbB2-dependent and ErbB2-independent mechanismsSMAD2 and SMAD7 involvement in the post-translational regulation of Muc4 via the transforming growth factor-beta and interferon-gamma pathways in rat mammary epithelial cellsSynthesis and secretion of Muc4/sialomucin complex: implication of intracellular proteolysisRegulation of the membrane mucin Muc4 in corneal epithelial cells by proteosomal degradation and TGF-betaThe fibroblast-derived paracrine factor neuregulin-1 has a novel role in regulating the constitutive color and melanocyte function in human skinCloning and characterization of the 5' flanking region of the sialomucin complex/rat Muc4 gene: promoter activity in cultured cells.Selection of peptides and synthesis of pentameric peptabody molecules reacting specifically with ErbB-2 receptor.Transcript profiling of Elf5+/- mammary glands during pregnancy identifies novel targets of Elf5.Cloning, chromosomal localization and characterization of the murine mucin gene orthologous to human MUC4.Muc4/MUC4 functions and regulation in cancerOverexpression of ErbB2 in cancer and ErbB2-targeting strategies.Mechanistic and signaling analysis of Muc4-ErbB2 signaling module: new insights into the mechanism of ligand-independent ErbB2 activity.Upregulation of MUC4 in cervical squamous cell carcinoma: pathologic significance.Genomic organization of MUC4 mucin gene. Towards the characterization of splice variants.Expression of mucins (MUC1, MUC2, MUC3, MUC4, MUC5AC and MUC6) and their prognostic significance in human breast cancer.The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesisMucin-interacting proteins: from function to therapeutics.IL-4 induced MUC4 enhancement in respiratory epithelial cells in vitro is mediated through JAK-3 selective signaling.Muc4-ErbB2 complex formation and signaling in polarized CACO-2 epithelial cells indicate that Muc4 acts as an unorthodox ligand for ErbB2Expression of mucins in mucoid otitis media.Alterations of MUC1 and MUC3 expression in gastric carcinoma: relevance to patient clinicopathological featuresMUC4 expression is a novel prognostic factor in patients with invasive ductal carcinoma of the pancreas.Distribution and partial characterisation of IgG Fc binding protein in various mucin producing cells and body fluids.Negative regulation of ErbB family receptor tyrosine kinasesPrognostic Role of Mucin Antigen MUC4 for Cholangiocarcinoma: A Meta-Analysis.Upregulation of mucin4 in ER-positive/HER2-overexpressing breast cancer xenografts with acquired resistance to endocrine and HER2-targeted therapiesPrognostic significance of membrane-associated mucins 1 and 4 in gastric adenocarcinoma.Activation of ErbB2 receptor tyrosine kinase supports invasion of endothelial cells by Neisseria meningitidis.Molecular Mechanisms of Trastuzumab-Based Treatment in HER2-Overexpressing Breast CancerMUC4 mucin expression in human pancreatic tumours is affected by organ environment: the possible role of TGFbeta2
P2860
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P2860
An intramembrane modulator of the ErbB2 receptor tyrosine kinase that potentiates neuregulin signaling
description
1999 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1999
@ast
im Februar 1999 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1999/02/26)
@sk
vědecký článek publikovaný v roce 1999
@cs
wetenschappelijk artikel (gepubliceerd op 1999/02/26)
@nl
наукова стаття, опублікована в лютому 1999
@uk
name
An intramembrane modulator of ...... tentiates neuregulin signaling
@ast
An intramembrane modulator of ...... tentiates neuregulin signaling
@en
An intramembrane modulator of ...... tentiates neuregulin signaling
@nl
type
label
An intramembrane modulator of ...... tentiates neuregulin signaling
@ast
An intramembrane modulator of ...... tentiates neuregulin signaling
@en
An intramembrane modulator of ...... tentiates neuregulin signaling
@nl
prefLabel
An intramembrane modulator of ...... tentiates neuregulin signaling
@ast
An intramembrane modulator of ...... tentiates neuregulin signaling
@en
An intramembrane modulator of ...... tentiates neuregulin signaling
@nl
P2093
P3181
P356
P1476
An intramembrane modulator of ...... tentiates neuregulin signaling
@en
P2093
C. A. Carraway
E. A. Rossi
K. L. Carraway
M. E. Carvajal
M. Komatsu
N. Fregien
S. A. Price-Schiavi
P304
P3181
P356
10.1074/JBC.274.9.5263
P407
P577
1999-02-26T00:00:00Z