Identification of osteoblast/osteocyte factor 45 (OF45), a bone-specific cDNA encoding an RGD-containing protein that is highly expressed in osteoblasts and osteocytes
about
Regulation of bone-renal mineral and energy metabolism: the PHEX, FGF23, DMP1, MEPE ASARM pathwayFGF23, PHEX, and MEPE regulation of phosphate homeostasis and skeletal mineralizationSix genes expressed in bones and teeth encode the current members of the SIBLING family of proteinsThree SIBLINGs (small integrin-binding ligand, N-linked glycoproteins) enhance factor H's cofactor activity enabling MCP-like cellular evasion of complement-mediated attackRole of matrix extracellular phosphoglycoprotein in the pathogenesis of X-linked hypophosphatemiaIncreased expression of matrix extracellular phosphoglycoprotein (MEPE) in cortical bone of the rat tibia after mechanical loading: identification by oligonucleotide microarrayCloning and characterization of osteoactivin, a novel cDNA expressed in osteoblastsMatrix extracellular phosphoglycoprotein inhibits phosphate transportTargeted disruption of the osteoblast/osteocyte factor 45 gene (OF45) results in increased bone formation and bone massMEPE is a novel regulator of growth plate cartilage mineralizationTranscriptional profiling of mesenchymal stromal cells from young and old rats in response to Dexamethasone.MEPE/OF45 as a new target for sensitizing human tumour cells to DNA damage inducersMepe is expressed during skeletal development and regeneration.A small peptide mimicking the key domain of MEPE/OF45 interacting with CHK1 protects human cells from radiation-induced killing.DLX3 regulates bone mass by targeting genes supporting osteoblast differentiation and mineral homeostasis in vivoAdaptive evolution of the matrix extracellular phosphoglycoprotein in mammalsMEPE/OF45, a new dentin/bone matrix protein and candidate gene for dentin diseases mapping to chromosome 4q21.Expression and processing of small integrin-binding ligand N-linked glycoproteins in mouse odontoblastic cells.Gene expression profiling in osteoclast precursors by insulin using microarray analysis.Evidence for a bone-kidney axis regulating phosphate homeostasis.MEPE expression in osteocytes during orthodontic tooth movementThe wrickkened pathways of FGF23, MEPE and PHEX.Serum MEPE-ASARM-peptides are elevated in X-linked rickets (HYP): implications for phosphaturia and rickets.Phosphorylated acidic serine-aspartate-rich MEPE-associated motif peptide from matrix extracellular phosphoglycoprotein inhibits phosphate regulating gene with homologies to endopeptidases on the X-chromosome enzyme activityCorrection of the mineralization defect in hyp mice treated with protease inhibitors CA074 and pepstatinSurface plasmon resonance (SPR) confirms that MEPE binds to PHEX via the MEPE-ASARM motif: a model for impaired mineralization in X-linked rickets (HYP)The chicken or the egg: PHEX, FGF23 and SIBLINGs unscrambled.Emerging role of a phosphatonin in mineral homeostasis and its derangements.Genetic analysis of vertebral trabecular bone density and cross-sectional area in older men.Impaired bone development and increased mesenchymal progenitor cells in calvaria of RB1-/- mice.Regulation of CYP27B1 mRNA Expression in Primary Human OsteoblastsMicroRNA-376a sensitizes cells following DNA damage by downregulating MEPE expression.Relationship between plasma fibroblast growth factor-23 concentration and bone mineralization in children with renal failure on peritoneal dialysis.Cell culture systems for studies of bone and tooth mineralization.SCPP gene evolution and the dental mineralization continuum.Targeted ablation of the PTH/PTHrP receptor in osteocytes impairs bone structure and homeostatic calcemic responsesPhosphorylated proteins and control over apatite nucleation, crystal growth, and inhibition.Molecular regulation of matrix extracellular phosphoglycoprotein expression by bone morphogenetic protein-2MEPE/OF45 protects cells from DNA damage induced killing via stabilizing CHK1.The rachitic tooth.
P2860
Q27026805-7AE66F9C-29E1-488D-9F64-EF17066DF962Q28177435-0958D677-1E0D-4576-9F07-BA675EBA5E9EQ28204658-2445F257-8718-47C6-965F-FB349911B545Q28217300-B1C1AD40-68AC-4F25-8579-94A85F7A099BQ28511009-18F52997-A685-4AA4-8437-F85958DB3F1CQ28534953-54151471-E4E5-4C30-85A7-4B4341F2E3A6Q28573446-88F1CA7A-9632-4F7D-B9F9-899F717F5888Q28578021-5A6E4363-E028-4BD3-9CC6-CA591481C5A5Q28589622-4E3BE13F-61A2-47BA-BB1A-0C3714012D5DQ28593877-6397AE48-F870-4E49-A1E5-57394898837DQ33241387-10B721AD-B7FB-4236-A90D-4AB454B59475Q33708170-0B966681-75C9-4334-BE92-7CD7A4E535ECQ33754716-F9B89D47-694F-4F50-97B7-363AD240C8CBQ33829188-60BFE664-547A-4A4D-A463-A9BB59B107D2Q34038429-E9E5F167-7A07-445E-B228-D55E8D2A21EBQ34079417-415B1A8E-3107-4358-9A8B-02A6E23C3F63Q34165637-E4A70C2A-89EB-4CA4-A62A-CF2DE099FE97Q34402367-21BA4640-F636-41AB-B676-C27CB0032A5FQ34628262-2FBB01D0-9E2B-49DD-9E10-A0A196BC7584Q35679294-D628EB09-933A-446F-B858-CF52617936D2Q35792574-4A279F52-A1D3-4188-80E2-C6F04E00D14FQ35911345-3C0367AA-E498-463B-BC9A-02A6C64D27C4Q35975734-537D5033-29EB-499B-844F-31E35E2A5B47Q35975746-5323E420-E557-4A90-8943-4CF59B02E205Q35983157-FCEE6E9F-0D2E-4662-8028-3BD6D4F1C32DQ35992810-AEF648B4-0DF8-46AC-9166-262602D73229Q36074718-788C24C0-DFF8-4377-A53F-CA0CA847AC55Q36554782-F24670DE-D3F5-4BCA-BC91-819864F76AD4Q36951167-C23AAE6E-4F32-4296-A946-C9B68CBB68DAQ36977862-41F0698C-D6AB-431D-8576-7B894DC03F21Q37063172-943B6B54-D0C6-479E-BB8C-FE51DD08042AQ37089955-0ECA3793-0553-403D-9C71-7250532E0F57Q37106569-FC9390A4-097D-45D8-8667-50C23E6EBA6AQ37121600-99B36B20-39C4-4E65-A249-15C8320B2A3BQ37173092-20A17B5E-5108-4171-B0D9-B326F0517D40Q37199498-D75B13D5-272D-4C0D-BDFF-D616516CB28AQ37285119-ED1787F1-2669-4313-888A-F0B2C4CC02DBQ37375766-F22B0241-3E5C-4FF3-866D-84844BAB7B2FQ37477525-E369EE8C-70BA-4FD1-85AC-A2F04BDE928DQ37493998-28E5C1BE-7B05-4858-9488-BB1146A02BFB
P2860
Identification of osteoblast/osteocyte factor 45 (OF45), a bone-specific cDNA encoding an RGD-containing protein that is highly expressed in osteoblasts and osteocytes
description
2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2000
@ast
im November 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/11/17)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/11/17)
@nl
наукова стаття, опублікована в листопаді 2000
@uk
name
Identification of osteoblast/o ...... in osteoblasts and osteocytes
@ast
Identification of osteoblast/o ...... in osteoblasts and osteocytes
@en
Identification of osteoblast/o ...... in osteoblasts and osteocytes
@nl
type
label
Identification of osteoblast/o ...... in osteoblasts and osteocytes
@ast
Identification of osteoblast/o ...... in osteoblasts and osteocytes
@en
Identification of osteoblast/o ...... in osteoblasts and osteocytes
@nl
prefLabel
Identification of osteoblast/o ...... in osteoblasts and osteocytes
@ast
Identification of osteoblast/o ...... in osteoblasts and osteocytes
@en
Identification of osteoblast/o ...... in osteoblasts and osteocytes
@nl
P2093
P2860
P3181
P356
P1476
Identification of osteoblast/o ...... in osteoblasts and osteocytes
@en
P2093
A. L. Mansolf
D. N. Petersen
G. T. Tkalcevic
R. Rivera-Gonzalez
T. A. Brown
P2860
P304
36172–36180
P3181
P356
10.1074/JBC.M003622200
P407
P577
2000-11-17T00:00:00Z