The scaffold protein Homer1b/c links metabotropic glutamate receptor 5 to extracellular signal-regulated protein kinase cascades in neurons
about
The Homer family proteinsRole of PDZ proteins in regulating trafficking, signaling, and function of GPCRs: means, motif, and opportunityCocaine activates Homer1 immediate early gene transcription in the mesocorticolimbic circuit: differential regulation by dopamine and glutamate signalingAmphetamine alters Ras-guanine nucleotide-releasing factor expression in the rat striatum in vivoDisassembly of shank and homer synaptic clusters is driven by soluble beta-amyloid(1-40) through divergent NMDAR-dependent signalling pathwaysRegulation of GPCR activity, trafficking and localization by GPCR-interacting proteins.VU0477573: Partial Negative Allosteric Modulator of the Subtype 5 Metabotropic Glutamate Receptor with In Vivo EfficacyUncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease.The type I inositol 1,4,5-trisphosphate receptor interacts with protein 4.1N to mediate neurite formation through intracellular Ca wavesDisrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome.Long-lasting impairment of mGluR5-activated intracellular pathways in the striatum after withdrawal of cocaine self-administrationPostsynaptic scaffold protein Homer 1a protects against traumatic brain injury via regulating group I metabotropic glutamate receptors.Regulation of group I metabotropic glutamate receptor expression in the rat striatum and prefrontal cortex in response to amphetamine in vivoMicroarray analysis on human neuroblastoma cells exposed to aluminum, β(1-42)-amyloid or the β(1-42)-amyloid aluminum complex.Sensitivity to theta-burst timing permits LTP in dorsal striatal adult brain slice.Dysregulation of group-I metabotropic glutamate (mGlu) receptor mediated signalling in disorders associated with Intellectual Disability and AutismExtinction training after cocaine self-administration induces glutamatergic plasticity to inhibit cocaine seeking.Chronic corticosterone administration down-regulates metabotropic glutamate receptor 5 protein expression in the rat hippocampus.Successful cognitive aging in rats: a role for mGluR5 glutamate receptors, homer 1 proteins and downstream signaling pathways.Therapeutic molecules and endogenous ligands regulate the interaction between brain cellular prion protein (PrPC) and metabotropic glutamate receptor 5 (mGluR5).Metabotropic glutamate receptor 5/Homer interactions underlie stress effects on fearIncreasing our understanding of human cognition through the study of Fragile X Syndrome.Frontier of epilepsy research - mTOR signaling pathway.Homer protein-metabotropic glutamate receptor binding regulates endocannabinoid signaling and affects hyperexcitability in a mouse model of fragile X syndrome.Identification of novel GRM1 mutations and single nucleotide polymorphisms in prostate cancer cell lines and tissues.Dynamic loss of surface-expressed AMPA receptors in mouse cortical and striatal neurons during anesthesia.Using c-fos to study neuronal ensembles in corticostriatal circuitry of addiction.An emerging role for the Mammalian target of rapamycin in "pathological" protein translation: relevance to cocaine addiction.RGS4 overexpression in the rat dorsal striatum modulates mGluR5- and amphetamine-mediated behavior and signaling.Role of mGluR5 neurotransmission in reinstated cocaine-seekingChronic treatment with lithium or valproate modulates the expression of Homer1b/c and its related genes Shank and Inositol 1,4,5-trisphosphate receptor.Dynamic remodeling of scaffold interactions in dendritic spines controls synaptic excitability.The sigma-1 receptor mediates the beneficial effects of pridopidine in a mouse model of Huntington diseaseEffects of Vesl/Homer proteins on intracellular signaling.The "ups and downs" of signaling cascades in addiction.Group I metabotropic glutamate receptor-mediated gene transcription and implications for synaptic plasticity and diseases.Metabotropic glutamate receptor 5 couples cellular prion protein to intracellular signalling in Alzheimer's diseaseMetabotropic glutamate receptor I (mGluR1) antagonism impairs cocaine-induced conditioned place preference via inhibition of protein synthesis.Melanoma cell adhesion molecule stimulates yes-associated protein transcription by enhancing CREB activity via c-Jun/c-Fos in hepatocellular carcinoma cellsThe role of Homer1c in metabotropic glutamate receptor-dependent long-term potentiation.
P2860
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P2860
The scaffold protein Homer1b/c links metabotropic glutamate receptor 5 to extracellular signal-regulated protein kinase cascades in neurons
description
2005 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im März 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/03/09)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/03/09)
@nl
наукова стаття, опублікована в березні 2005
@uk
مقالة علمية (نشرت في 9-3-2005)
@ar
name
The scaffold protein Homer1b/c ...... ein kinase cascades in neurons
@ast
The scaffold protein Homer1b/c ...... ein kinase cascades in neurons
@en
The scaffold protein Homer1b/c ...... ein kinase cascades in neurons
@nl
type
label
The scaffold protein Homer1b/c ...... ein kinase cascades in neurons
@ast
The scaffold protein Homer1b/c ...... ein kinase cascades in neurons
@en
The scaffold protein Homer1b/c ...... ein kinase cascades in neurons
@nl
prefLabel
The scaffold protein Homer1b/c ...... ein kinase cascades in neurons
@ast
The scaffold protein Homer1b/c ...... ein kinase cascades in neurons
@en
The scaffold protein Homer1b/c ...... ein kinase cascades in neurons
@nl
P2093
P3181
P1476
The scaffold protein Homer1b/c ...... ein kinase cascades in neurons
@en
P2093
Guochi Zhang
John Q Wang
Qingsong Tang
Shazia Samdani
P304
P3181
P356
10.1523/JNEUROSCI.4360-04.2005
P407
P577
2005-03-01T00:00:00Z