Molecular cloning of phogrin, a protein-tyrosine phosphatase homologue localized to insulin secretory granule membranes
about
In type 1 diabetes a subset of anti-coxsackievirus B4 antibodies recognize autoantigens and induce apoptosis of pancreatic beta cellsbetaIV spectrin, a new spectrin localized at axon initial segments and nodes of ranvier in the central and peripheral nervous systemThe neurosecretory vesicle protein phogrin functions as a phosphatidylinositol phosphatase to regulate insulin secretionDominant-negative behavior of mammalian Vps35 in yeast requires a conserved PRLYL motif involved in retromer assemblyNovel diabetes autoantibodies and prediction of type 1 diabetesImmunogenetics of type 1 diabetes mellitusMultimerization of the protein-tyrosine phosphatase (PTP)-like insulin-dependent diabetes mellitus autoantigens IA-2 and IA-2beta with receptor PTPs (RPTPs). Inhibition of RPTPalpha enzymatic activityThe diabetes autoantigen ICA69 and its Caenorhabditis elegans homologue, ric-19, are conserved regulators of neuroendocrine secretionOverexpression of a rat kinase-deficient phosphoinositide 3-kinase, Vps34p, inhibits cathepsin D maturationDisturbances in the secretion of neurotransmitters in IA-2/IA-2beta null mice: changes in behavior, learning and lifespan.A subset of p23 localized on secretory granules in pancreatic beta-cellsMyosin Va transports dense core secretory vesicles in pancreatic MIN6 beta-cellsDiscovery of novel vitamin D-regulated proteins in INS-1 cells: a proteomic approachT-cadherin (Cdh13) in association with pancreatic β-cell granules contributes to second phase insulin secretionCholesterol accumulation increases insulin granule size and impairs membrane trafficking.Monitoring of exocytosis and endocytosis of insulin secretory granules in the pancreatic beta-cell line MIN6 using pH-sensitive green fluorescent protein (pHluorin) and confocal laser microscopyPatterns of gene expression in the developing adult sea urchin central nervous system reveal multiple domains and deep-seated neural pentamery.IDA-1, a Caenorhabditis elegans homolog of the diabetic autoantigens IA-2 and phogrin, is expressed in peptidergic neurons in the worm.Secretory-granule dynamics visualized in vivo with a phogrin-green fluorescent protein chimaera.Insulin targeting to the regulated secretory pathway after fusion with green fluorescent protein and firefly luciferase.Developments in the prediction of type 1 diabetes mellitus, with special reference to insulin autoantibodies.Imaging a target of Ca2+ signalling: dense core granule exocytosis viewed by total internal reflection fluorescence microscopy.Loss of the transcriptional repressor PAG-3/Gfi-1 results in enhanced neurosecretion that is dependent on the dense-core vesicle membrane protein IDA-1/IA-2.DNA hypermethylation and DNA hypomethylation is present at different loci in chronic kidney diseasePhospholipase C-related catalytically inactive protein (PRIP) controls KIF5B-mediated insulin secretionHumoral autoimmunity against the extracellular domain of the neuroendocrine autoantigen IA-2 heightens the risk of type 1 diabetesIA-2beta, but not IA-2, is induced by ghrelin and inhibits glucose-stimulated insulin secretion.Trans-Golgi network sorting.Kinetics of the post-onset decline in zinc transporter 8 autoantibodies in type 1 diabetic human subjects.Secretory granules are recaptured largely intact after stimulated exocytosis in cultured endocrine cells.Aberrant Expression of proPTPRN2 in Cancer Cells Confers Resistance to Apoptosis.Tetrahymena: the key to the genetic analysis of the regulated pathway of polypeptide secretion?Prediction and prevention of type 1 diabetes: update on success of prediction and struggles at preventionLabel-free Quantitative Proteomics of Mouse Cerebrospinal Fluid Detects β-Site APP Cleaving Enzyme (BACE1) Protease Substrates In VivoMannose 6-phosphate receptors are sorted from immature secretory granules via adaptor protein AP-1, clathrin, and syntaxin 6-positive vesiclesHumoral autoimmunity in type 1 diabetes: prediction, significance, and detection of distinct disease subtypes.Association of genetic variants with chronic kidney disease in Japanese individuals with or without hypertension or diabetes mellitus.IA-2 modulates dopamine secretion in PC12 cells.PTPRN2 and PLCβ1 promote metastatic breast cancer cell migration through PI(4,5)P2-dependent actin remodeling.Insulin vesicle release: walk, kiss, pause ... then run.
P2860
Q21133650-A4E4F2C9-620F-4AE9-B1F0-E21DB321B9DDQ24290541-118744A8-842D-451E-8E0E-291F42970862Q24634647-B331E26E-4384-45AB-AC8F-097593C36B84Q24653391-9F0D6F12-4D8B-4C35-8C50-077A3954846EQ27016130-60F26CF5-FCCD-4B62-96CB-9AD3396CEE9FQ28087365-B720F9A7-9BDD-4619-9600-1143D9E678C7Q28205406-6684CEB3-A24C-45CD-A5DB-EEE1436EA7A5Q28344845-3226F2EC-1BA7-4DC9-A155-1A43BA2FE58FQ28347849-9B22E5CA-9EF7-4866-BB92-B24A1066D9CAQ28512746-FC6BD6C8-C8AE-45A1-9EF0-BE00BBF9EC11Q28573794-3B915EF8-D281-424A-97B9-C4CE57C41057Q28589310-056BA05B-1C54-44D5-982D-EC4520714201Q28854272-B5BB6179-3C6C-4C70-95D3-1302E05F5847Q30513489-51758E6F-AF39-4A3B-B6DE-43FB26DA5921Q30525535-50D8D755-D28E-4CB0-AADD-CD1A1C4DAEA0Q31043443-1FEB9271-93F7-4C57-BCD4-6ED07B47505AQ31072155-F0252F3E-E54B-491A-819F-FB6304066DB1Q31585217-CFAF1248-DCAF-4236-8CF2-604CAF20667AQ32060185-CB8CE086-1869-41B0-9CC0-666E6FDEC580Q32073156-07D97D0F-BC95-4AD3-AB96-08DAE2C57270Q33215130-BF3466CC-9BCF-44B2-B38C-A499DDF1A108Q33375889-FEE44EAF-1714-40B8-ADA2-0BE2B087F562Q33426357-D96CD847-B7C7-4C53-B2E7-FCD22C563012Q33740666-26948D21-F13A-4CB8-BC64-A9985AF12E66Q33757240-8F598CF7-52D0-428F-B226-F8695E663228Q33874516-EDA7A8BE-2E00-4C37-829F-A5E11052EDFAQ34304638-B16BC21C-E615-4224-A1D5-1182DDDF9EDFQ34350937-4B667FE3-7C90-4E6D-93CC-08EBC1E187F2Q34630695-0F301BC8-D382-4B19-BF43-85BDC6E4DFA7Q34763388-E566B89A-0273-424B-BC39-4D837010AC75Q35563028-273C7D37-14D2-433B-99CD-016CC23FD85EQ36038470-32CEBFB1-FD9A-45EF-A6B9-D18B73358435Q36117948-2EAF21E0-1F9E-42F7-A4A4-24918406135FQ36133947-F309B61C-3E1E-40A1-BF63-5BA7D888CB0AQ36289154-0834535F-36EE-43EE-9301-012872732666Q36330292-8E8C5068-513F-47DF-B588-CB179905FE6AQ36375307-E252E012-3894-42C5-A9B8-1F53DA28FC43Q36390368-DD69E245-0035-4792-8F3F-2FAFD9371BDFQ36477335-D60CC811-C1C8-4745-919F-4B06DEF46B72Q36484264-E2B88321-25E0-4398-BCDA-AD2839E0918C
P2860
Molecular cloning of phogrin, a protein-tyrosine phosphatase homologue localized to insulin secretory granule membranes
description
1996 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1996
@ast
im Juli 1996 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1996/07/26)
@sk
vědecký článek publikovaný v roce 1996
@cs
wetenschappelijk artikel (gepubliceerd op 1996/07/26)
@nl
наукова стаття, опублікована в липні 1996
@uk
name
Molecular cloning of phogrin, ...... in secretory granule membranes
@ast
Molecular cloning of phogrin, ...... in secretory granule membranes
@en
Molecular cloning of phogrin, ...... in secretory granule membranes
@nl
type
label
Molecular cloning of phogrin, ...... in secretory granule membranes
@ast
Molecular cloning of phogrin, ...... in secretory granule membranes
@en
Molecular cloning of phogrin, ...... in secretory granule membranes
@nl
prefLabel
Molecular cloning of phogrin, ...... in secretory granule membranes
@ast
Molecular cloning of phogrin, ...... in secretory granule membranes
@en
Molecular cloning of phogrin, ...... in secretory granule membranes
@nl
P2860
P3181
P356
P1476
Molecular cloning of phogrin, ...... in secretory granule membranes
@en
P2093
C. Wasmeier
J. C. Hutton
P2860
P304
18161–18170
P3181
P356
10.1074/JBC.271.30.18161
P407
P577
1996-07-26T00:00:00Z