Dally-like core protein and its mammalian homologues mediate stimulatory and inhibitory effects on Hedgehog signal response
about
Structural Aspects of N-Glycosylations and the C-terminal Region in Human Glypican-1.Structure of the protein core of the glypican Dally-like and localization of a region important for hedgehog signaling.Crystal Structure of N -Glycosylated Human Glypican-1 Core ProteinStructural insights into proteoglycan-shaped Hedgehog signalingSmoothened goes molecular: new pieces in the hedgehog signaling puzzleAltering Glypican-1 levels modulates canonical Wnt signaling during trigeminal placode developmentSpecific sides to multifaceted glycosaminoglycans are observed in embryonic development.Overlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway function.Ihog and Boi are essential for Hedgehog signaling in Drosophila.Drosophila Boi limits Hedgehog levels to suppress follicle stem cell proliferation.Glypican-5 stimulates rhabdomyosarcoma cell proliferation by activating Hedgehog signalingSimpson-Golabi-Behmel syndrome types I and II.Novel contact-dependent bone morphogenetic protein (BMP) signaling mediated by heparan sulfate proteoglycans.Design and characterization of a photo-activatable hedgehog probe that mimics the natural lipidated form.Glypican Is a Modulator of Netrin-Mediated Axon GuidanceA zebrafish Notum homolog specifically blocks the Wnt/β-catenin signaling pathwayAstrocyte glypicans 4 and 6 promote formation of excitatory synapses via GluA1 AMPA receptorsGlypicans regulate JAK/STAT signaling and distribution of the Unpaired morphogen.The Drosophila WIF1 homolog Shifted maintains glypican-independent Hedgehog signaling and interacts with the Hedgehog co-receptors Ihog and Boi.Critical analysis of the potential of targeting GPC3 in hepatocellular carcinoma.Interactions between Hedgehog proteins and their binding partners come into view.Boning up on glypicans--opportunities for new insights into bone biology.Distinct structural requirements for CDON and BOC in the promotion of Hedgehog signaling.Cysteine-rich domains related to Frizzled receptors and Hedgehog-interacting proteins.DSulfatase-1 fine-tunes Hedgehog patterning activity through a novel regulatory feedback loop.Regulation of TGFβ superfamily signaling by two separable domains of glypican LON-2 in C. elegans.Glypican-6 promotes the growth of developing long bones by stimulating Hedgehog signaling.Processing by convertases is required for glypican-3-induced inhibition of Hedgehog signaling.Two functional domains in C. elegans glypican LON-2 can independently inhibit BMP-like signaling.Perspectives on Intra- and Intercellular Trafficking of Hedgehog for Tissue Patterning.
P2860
Q27312438-B2AADE3C-FCB9-4543-A489-3C516E6B2D0EQ27671642-20B28C9E-2F40-4002-A4CC-A2A2192CE015Q27677391-ACAD1BDC-D10E-4FFD-A53E-0BED64E39F97Q27680033-EF00C210-83F7-44D7-AE8C-052D99A807B0Q33359720-936D0D3D-B0F7-4A02-A986-CA393F99B23FQ33849654-BE95C156-19DE-4E8A-BB07-99C11162BFA9Q34071237-F197AB75-A96A-44D8-B71C-5372DD047317Q34191681-89128AAD-8D56-4CDF-8CE9-23AE1C10DD14Q34321378-A61B7806-A87C-405E-B07C-22689EF002B1Q34368578-85897E9D-F30F-4902-802A-A7AB2A691FA5Q34600765-C2820AB6-3225-456F-8F73-E4F6B523078DQ34623852-59369C34-887D-47E5-9A44-C517EAB0E5F2Q34947988-AB69B219-FC45-48AD-8076-B6D12BDF579EQ35067788-09AB5C9B-CAB2-4AFF-BA5B-96C493C23118Q35684351-A5233170-8144-48FB-9CB4-6B6EC053341AQ36008971-38D13998-5EC1-47D3-BC02-7D675AB601A4Q36058143-5A18C002-098D-403E-96AD-C58E43BC51ADQ36340141-9263A2BB-F689-4DC6-BB59-52751E47F687Q36444136-4BA95915-DC2E-406A-B41C-870D7159ABE4Q37031710-BCCA66C7-C9B0-4C99-8AF0-33A0C9710F80Q37789106-B25E4BD2-25C5-4B88-8520-876228520EE1Q38072394-B7C1492D-1016-4DED-8D10-7092F0316357Q41107286-B277092F-F64F-41B8-9460-2E813950C5ECQ42022615-F55FCFDD-AD71-45E2-8B97-BA9FB62B4C89Q42072868-AD0C1408-A955-468A-B73F-D11F052F31A6Q42770522-09934356-4980-493B-A635-4031A40CC89DQ42799207-2490FD17-F859-4830-A144-C5DA63CA2615Q42830736-267738CE-6E1A-4995-A3E4-6318AD5CEFDDQ47102060-DCD731FB-A79E-496A-9764-55D8D9BC8958Q55322531-C1B7A161-DA9A-443C-9F4D-769366ABB303
P2860
Dally-like core protein and its mammalian homologues mediate stimulatory and inhibitory effects on Hedgehog signal response
description
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2010
@ast
im März 2010 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2010/03/30)
@sk
vědecký článek publikovaný v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/03/30)
@nl
наукова стаття, опублікована в березні 2010
@uk
name
Dally-like core protein and it ...... ts on Hedgehog signal response
@ast
Dally-like core protein and it ...... ts on Hedgehog signal response
@en
Dally-like core protein and it ...... ts on Hedgehog signal response
@nl
type
label
Dally-like core protein and it ...... ts on Hedgehog signal response
@ast
Dally-like core protein and it ...... ts on Hedgehog signal response
@en
Dally-like core protein and it ...... ts on Hedgehog signal response
@nl
prefLabel
Dally-like core protein and it ...... ts on Hedgehog signal response
@ast
Dally-like core protein and it ...... ts on Hedgehog signal response
@en
Dally-like core protein and it ...... ts on Hedgehog signal response
@nl
P2093
P2860
P356
P1476
Dally-like core protein and it ...... ts on Hedgehog signal response
@en
P2093
Adam M. Saunders
Daniel J. Leahy
Min-Sung Kim
Philip A. Beachy
William N. Pappano
P2860
P304
P356
10.1073/PNAS.1001777107
P407
P577
2010-03-30T00:00:00Z