Dickkopf-1 regulates bone formation in young growing rodents and upon traumatic injury
about
Targeting the Wnt pathways for therapiesThe osteocyte as a therapeutic target in the treatment of osteoporosisCurrent insights on the regenerative potential of the periosteum: molecular, cellular, and endogenous engineering approachesWNT signaling in bone homeostasis and disease: from human mutations to treatmentsAn appropriate Wnt/β-catenin expression level during the remodeling phase is required for improved bone fracture healing in miceAging periosteal progenitor cells have reduced regenerative responsiveness to bone injury and to the anabolic actions of PTH 1-34 treatment.Osteoblast-specific Krm2 overexpression and Lrp5 deficiency have different effects on fracture healing in mice.Role of Wnt signaling in fracture healingAnti-DKK1 antibody promotes bone fracture healing through activation of β-catenin signaling.Dkk1 haploinsufficiency requires expression of Bmp2 for bone anabolic activityHigh-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes.A transgenic, mesodermal specific, Dkk1 mouse model recapitulates a spectrum of human congenital limb reduction defects.Role of Wnt/β-catenin and RANKL/OPG in bone healing of diabetic Charcot arthropathy patients.Role of fibroblast growth factor 2 and Wnt signaling in anabolic effects of parathyroid hormone on bone formation.The bone-sparing effects of estrogen and WNT16 are independent of each otherWnt signaling in bone formation and its therapeutic potential for bone diseases.A bispecific antibody targeting sclerostin and DKK-1 promotes bone mass accrual and fracture repair.Transient Canonical Wnt Stimulation Enriches Human Bone Marrow Mononuclear Cell Isolates for Osteoprogenitors.Periosteum: biology and applications in craniofacial bone regeneration.Emerging therapies for the treatment of osteoporosisOsteocyte control of bone remodeling: is sclerostin a key molecular coordinator of the balanced bone resorption-formation cycles?Perspectives on osteoporosis therapies.The osteocyte plays multiple roles in bone remodeling and mineral homeostasis.The WNT system: background and its role in bone.Strong effect of SNP rs4988300 of the LRP5 gene on bone phenotype of Caucasian postmenopausal women.Investigational anabolic agents for the treatment of osteoporosis: an update on recent developments.Fracture healing physiology and the quest for therapies for delayed healing and nonunion.New Target Sites for Treatment of Osteoporosis.Exploiting the WNT Signaling Pathway for Clinical Purposes.In vivo hypobaric hypoxia performed during the remodeling process accelerates bone healing in miceMicroRNA-29a protects against glucocorticoid-induced bone loss and fragility in rats by orchestrating bone acquisition and resorption.Loss of Gi G-Protein-Coupled Receptor Signaling in Osteoblasts Accelerates Bone Fracture Healing.Vaccination with DKK1-derived peptides promotes bone formation and bone mass in an aged mouse osteoporosis model.Ibandronate increases sclerostin levels and bone strength in male patients with idiopathic osteoporosis.Thin bones: Vitamin D and calcium handling after bariatric surgery.Anabolic Strategies to Augment Bone Fracture Healing.Dkk-1-Mediated Inhibition of Wnt Signaling in Bone Ameliorates Osteoarthritis in MiceSclerostin and DKK1 in Primary Hyperparathyroidism
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P2860
Dickkopf-1 regulates bone formation in young growing rodents and upon traumatic injury
description
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2011
@ast
im November 2011 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2011/11/01)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/11/01)
@nl
наукова стаття, опублікована в листопаді 2011
@uk
مقالة علمية (نشرت في نوفمبر 2011)
@ar
name
Dickkopf-1 regulates bone formation in young growing rodents and upon traumatic injury
@ast
Dickkopf-1 regulates bone formation in young growing rodents and upon traumatic injury
@en
Dickkopf-1 regulates bone formation in young growing rodents and upon traumatic injury
@nl
type
label
Dickkopf-1 regulates bone formation in young growing rodents and upon traumatic injury
@ast
Dickkopf-1 regulates bone formation in young growing rodents and upon traumatic injury
@en
Dickkopf-1 regulates bone formation in young growing rodents and upon traumatic injury
@nl
prefLabel
Dickkopf-1 regulates bone formation in young growing rodents and upon traumatic injury
@ast
Dickkopf-1 regulates bone formation in young growing rodents and upon traumatic injury
@en
Dickkopf-1 regulates bone formation in young growing rodents and upon traumatic injury
@nl
P2093
P2860
P3181
P356
P1476
Dickkopf-1 regulates bone formation in young growing rodents and upon traumatic injury
@en
P2093
Aaron Winters
Barbara Tipton
Chaoyang Li
Chun-Ya Han
David L. Lacey
Denise Dwyer
Edward Lee
Eliane G. Valente
Frank J. Asuncion
Frederick Jacobsen
P2860
P304
P3181
P356
10.1002/JBMR.472
P577
2011-11-01T00:00:00Z