The RGS14 GoLoco domain discriminates among Galphai isoforms
about
Localization of Gi alpha proteins in the centrosomes and at the midbody: implication for their role in cell division.Activators of G protein signaling in the kidneyActivators of G protein signaling exhibit broad functionality and define a distinct core signaling triadRGS14 at the interface of hippocampal signaling and synaptic plasticityRGS14 is a multifunctional scaffold that integrates G protein and Ras/Raf MAPkinase signalling pathwaysIdentification and characterization of a G-protein regulatory motif in WAVE1Activation of the regulator of G protein signaling 14-Gαi1-GDP signaling complex is regulated by resistance to inhibitors of cholinesterase-8ARegulator of G-protein signaling 14 (RGS14) is a selective H-Ras effectorEvolution of class-specific peptides targeting a hot spot of the Galphas subunit.G Protein binding sites on Calnuc (nucleobindin 1) and NUCB2 (nucleobindin 2) define a new class of G(alpha)i-regulatory motifsG protein-coupled receptors and resistance to inhibitors of cholinesterase-8A (Ric-8A) both regulate the regulator of g protein signaling 14 RGS14·Gαi1 complex in live cellsIntegration of G protein α (Gα) signaling by the regulator of G protein signaling 14 (RGS14).How regulators of G protein signaling achieve selective regulation.Mechanistic pathways and biological roles for receptor-independent activators of G-protein signaling.Roles for Regulator of G Protein Signaling Proteins in Synaptic Signaling and Plasticity.Assembly and function of the regulator of G protein signaling 14 (RGS14)·H-Ras signaling complex in live cells are regulated by Gαi1 and Gαi-linked G protein-coupled receptors.The Ras-binding domain region of RGS14 regulates its functional interactions with heterotrimeric G proteins.Postnatal developmental expression of regulator of G protein signaling 14 (RGS14) in the mouse brain.Group II activators of G-protein signalling and proteins containing a G-protein regulatory motif.Regulator of G protein signaling 14 (RGS14) is expressed pre- and postsynaptically in neurons of hippocampus, basal ganglia, and amygdala of monkey and human brain.GoLoco motif proteins binding to Galpha(i1): insights from molecular simulations.Biochemical characterization of RGS14: RGS14 activity towards G-protein alpha subunits is independent of its binding to Rap2A.D2 dopamine receptor activation of potassium channels is selectively decoupled by Galpha-specific GoLoco motif peptides.RGS14 regulates the lifetime of Gα-GTP signaling but does not prolong Gβγ signaling following receptor activation in live cells.Endogenous RGS14 is a cytoplasmic-nuclear shuttling protein that localizes to juxtanuclear membranes and chromatin-rich regions of the nucleusRic-8A, an activator protein of Gαi, controls mammalian epithelial cell polarity for tight junction assembly and cystogenesis.A peptide core motif for binding to heterotrimeric G protein alpha subunits.Genetic Analysis of Rare Human Variants of Regulators of G Protein Signaling Proteins and Their Role in Human Physiology and Disease
P2860
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P2860
The RGS14 GoLoco domain discriminates among Galphai isoforms
description
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2004
@ast
im November 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/11/05)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/11/05)
@nl
наукова стаття, опублікована в листопаді 2004
@uk
name
The RGS14 GoLoco domain discriminates among Galphai isoforms
@ast
The RGS14 GoLoco domain discriminates among Galphai isoforms
@en
The RGS14 GoLoco domain discriminates among Galphai isoforms
@nl
type
label
The RGS14 GoLoco domain discriminates among Galphai isoforms
@ast
The RGS14 GoLoco domain discriminates among Galphai isoforms
@en
The RGS14 GoLoco domain discriminates among Galphai isoforms
@nl
prefLabel
The RGS14 GoLoco domain discriminates among Galphai isoforms
@ast
The RGS14 GoLoco domain discriminates among Galphai isoforms
@en
The RGS14 GoLoco domain discriminates among Galphai isoforms
@nl
P2860
P3181
P356
P1476
The RGS14 GoLoco domain discriminates among Galphai isoforms
@en
P2093
Maurine E. Linder
Vivek Mittal
P2860
P304
46772–46778
P3181
P356
10.1074/JBC.M407409200
P407
P577
2004-11-05T00:00:00Z