Loss of murine Na+/myo-inositol cotransporter leads to brain myo-inositol depletion and central apnea
about
Phosphoinositides: tiny lipids with giant impact on cell regulationKCNQ1, KCNE2, and Na+-coupled solute transporters form reciprocally regulating complexes that affect neuronal excitabilityLithium and bipolar mood disorder: the inositol-depletion hypothesis revisitedMolecular actions and clinical pharmacogenetics of lithium therapyDefective craniofacial development and brain function in a mouse model for depletion of intracellular inositol synthesis.A guide to the metabolic pathways and function of metabolites observed in human brain 1H magnetic resonance spectra.Identification of a mutation associated with fatal Foal Immunodeficiency Syndrome in the Fell and Dales pony.Role of an expanded inositol transporter repertoire in Cryptococcus neoformans sexual reproduction and virulenceInnovative therapy for Classic Galactosemia - tale of two HTS.Regulated exocytosis of an H+/myo-inositol symporter at synapses and growth cones.The App-Runx1 region is critical for birth defects and electrocardiographic dysfunctions observed in a Down syndrome mouse model.myo-Inositol uptake is essential for bulk inositol phospholipid but not glycosylphosphatidylinositol synthesis in Trypanosoma brucei.Fell Pony syndrome: characterization of developmental hematopoiesis failure and associated gene expression profiles.Expression Profiling of Solute Carrier Gene Families at the Blood-CSF Barrier.TonEBP and SMIT expression in human placentaInositol-related gene knockouts mimic lithium's effect on mitochondrial function.Ion channel-transporter interactions.Validating GSK3 as an in vivo target of lithium action.Sodium-myoinositol cotransporter-1, SMIT1, mediates the production of reactive oxygen species induced by hyperglycemia in the heart.IP3 accumulation and/or inositol depletion: two downstream lithium's effects that may mediate its behavioral and cellular changes.The betaine/GABA transporter and betaine: roles in brain, kidney, and liver.Is prenatal myo-inositol deficiency a mechanism of CNS injury in galactosemia?Inositol transport proteins.Candida albicans uses multiple mechanisms to acquire the essential metabolite inositol during infection.Chansporter complexes in cell signaling.Sodium/myo-inositol cotransporter 1 and myo-inositol are essential for osteogenesis and bone formation.Characterization of the expression and regulation of genes necessary for myo-inositol biosynthesis and transport in the seminiferous epithelium.Human myo-inositol monophosphatase 2 rescues the nematode thermotaxis mutant ttx-7 more efficiently than IMPA1: functional and evolutionary considerations of the two mammalian myo-inositol monophosphatase genes.KCNQ-SMIT complex formation facilitates ion channel-solute transporter cross talk.SMIT1 Modifies KCNQ Channel Function and Pharmacology by Physical Interaction with the Pore.Homozygote inositol transporter knockout mice show a lithium-like phenotype.Automatic classification of activity and apneas using whole body plethysmography in newborn mice.Behavioural phenotyping of sodium-myo-inositol cotransporter heterozygous knockout mice with reduced brain inositol.A homozygous loss-of-function mutation in inositol monophosphatase 1 (IMPA1) causes severe intellectual disability.
P2860
Q27012953-5DF8B13E-649B-4087-8881-112BCFE080CBQ28235219-3F928E47-D0BF-437E-94B3-0797969B7EEFQ28294604-EFBFD289-069D-47D2-B863-DEB6DF063071Q28307770-0A1BF628-655E-43A0-8B85-11E318C28EF5Q30414460-18AEE700-7883-4F8D-AB5D-B2A8DE7ECEC5Q30698264-8C1C445A-41EC-4FAF-AC62-5038F32F8DBEQ33959213-D9B1615B-7D8B-465C-81D7-94A4D74EA565Q34030598-E93E0385-E6DC-482B-A500-FB3C5C4694C2Q34054239-5866E7E2-75E8-459E-968E-C03810151836Q34107636-4E3DB957-468C-4BC0-B6BA-1E5716970B0AQ34302163-8C1C64B4-219C-444F-89CB-FA6BC314EF6FQ35921715-C7409FBF-DFEE-4336-957A-DC6ACE79E476Q36086228-4F4931A1-C42D-4E66-91F5-5E73ADD0D89CQ36186589-9CA88041-B601-4D4C-A0FE-DAC59C69CE2DQ36319928-7F4AA3C0-B644-479F-B26E-4511E978D8F8Q37409627-4CC3AFFE-5072-471F-B9D4-43925EBD18A0Q37562039-0C7C14A0-3B44-49F1-B3D6-C41BDBDB47A7Q37597409-49297148-26CE-4414-A7F7-1EAA1050251EQ37609275-D2DCA455-DCE0-4AB0-8656-315454A043E7Q37650454-535C807D-D15E-42A0-8EB0-74F9C336E053Q37735049-A745B80D-5253-4D2B-BD83-DC1C5468BD8BQ37829953-BBCDDD56-2EBE-4DE1-8D98-75C85C15586FQ38394774-BE3A76D4-8532-42E5-B5C3-9C0C3585ABC7Q39023515-AE1F96C5-5EAB-465A-9951-EB6DE5FA4D5FQ39441418-5CA9B520-1616-4552-A1F1-6EBF7063E994Q39659199-0D662B05-DF4D-4A72-9DB3-8B721F2D2A16Q44653167-0DFEE91A-8624-494D-BF80-6AEE9844EDDCQ45405500-AE48624A-9F63-4982-AC93-B3A0E3AE612DQ45996705-11ABD9F1-CB30-4B0C-AFC8-93F35FE5DA23Q46094945-0216C1CA-1D04-418E-96F3-8AF47064BE4DQ46614951-26F92C88-E25D-405F-BBDA-F21757B7EFB6Q47881781-6A74040B-CAE8-4EA2-B221-C94BFECCBBBCQ48468698-AE574789-D9FE-41BE-A844-569BC7F1CA07Q55059337-8A12E6F4-1C7C-41EE-8EDA-B67AA60F0650
P2860
Loss of murine Na+/myo-inositol cotransporter leads to brain myo-inositol depletion and central apnea
description
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2003
@ast
im Mai 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/05/16)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/05/16)
@nl
наукова стаття, опублікована в травні 2003
@uk
name
Loss of murine Na+/myo-inosito ...... ol depletion and central apnea
@ast
Loss of murine Na+/myo-inosito ...... ol depletion and central apnea
@en
Loss of murine Na+/myo-inosito ...... ol depletion and central apnea
@nl
type
label
Loss of murine Na+/myo-inosito ...... ol depletion and central apnea
@ast
Loss of murine Na+/myo-inosito ...... ol depletion and central apnea
@en
Loss of murine Na+/myo-inosito ...... ol depletion and central apnea
@nl
prefLabel
Loss of murine Na+/myo-inosito ...... ol depletion and central apnea
@ast
Loss of murine Na+/myo-inosito ...... ol depletion and central apnea
@en
Loss of murine Na+/myo-inosito ...... ol depletion and central apnea
@nl
P2093
P356
P1476
Loss of murine Na+/myo-inosito ...... ol depletion and central apnea
@en
P2093
Jeffrey A. Golden
John J. Greer
Linda W. Gonzales
Martin J. Stevens
Philip L. Ballard
Roberto Buccafusca
P304
18297–18302
P356
10.1074/JBC.M213176200
P407
P50
P577
2003-05-16T00:00:00Z