Resistance to experimental autoimmune encephalomyelitis and impaired IL-17 production in protein kinase C theta-deficient mice
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A motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synapse and functions in T cells via association with CD28The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cellsPromising new treatments for psoriasisPKC-Theta in Regulatory and Effector T-cell FunctionsThe Novel PKCθ from Benchtop to ClinicPKCθ/β and CYLD are antagonistic partners in the NFκB and NFAT transactivation pathways in primary mouse CD3+ T lymphocytesProtein kinase C θ regulates the phenotype of murine CD4+ Th17 cellsProtein kinase C in the immune system: from signalling to chromatin regulationOverexpression of Ste20-related proline/alanine-rich kinase exacerbates experimental colitis in miceChemical proteomic map of dimethyl fumarate-sensitive cysteines in primary human T cellsGenetic analysis of the role of protein kinase Ctheta in platelet function and thrombus formationThe SWI/SNF chromatin-remodeling complex modulates peripheral T cell activation and proliferation by controlling AP-1 expression.Regulatory T cells and Toll-like receptors: what is the missing link?Pharmacological Inhibition of PKCθ Counteracts Muscle Disease in a Mouse Model of Duchenne Muscular Dystrophy.Protective Toxoplasma gondii-specific T-cell responses require T-cell-specific expression of protein kinase C-theta.Protein kinase C θ deficiency increases resistance of C57BL/6J mice to Plasmodium berghei infection-induced cerebral malaria.Inhibition of PKC-θ preserves cardiac function and reduces fibrosis in streptozotocin-induced diabetic cardiomyopathyChronic activation of the kinase IKKβ impairs T cell function and survival.Chromatinized Protein Kinase C-θ: Can It Escape the Clutches of NF-κB?Protein kinase C theta is required for efficient induction of IL-10-secreting T cells.Protein kinase C theta is dispensable for suppression mediated by CD25+CD4+ regulatory T cells.The emerging role of protein kinase Cθ in cytoskeletal signaling.Systems-based medicine approaches to understand and treat complex diseases. The example of multiple sclerosis.Th17 cell induction and immune regulatory effects.A critical role for protein kinase C-theta-mediated T cell survival in cardiac allograft rejection.IRAK4 kinase activity is required for Th17 differentiation and Th17-mediated disease.Protein kinase C theta (PKCtheta): a key player in T cell life and deathThe nuclear orphan receptor NR2F6 suppresses lymphocyte activation and T helper 17-dependent autoimmunityThe inflammatory Th 17 subset in immunity against self and non-self antigens.Differential requirement of PKC-theta in the development and function of natural regulatory T cells.PRKCQ promotes oncogenic growth and anoikis resistance of a subset of triple-negative breast cancer cells.Induction, function and regulation of IL-17-producing T cells.The yin and yang of protein kinase C-theta (PKCθ): a novel drug target for selective immunosuppression.Systematically characterizing dysfunctional long intergenic non-coding RNAs in multiple brain regions of major psychosis.PKC-θ is a drug target for prevention of T cell-mediated autoimmunity and allograft rejection.PKC-θ function at the immunological synapse: prospects for therapeutic targeting.Protein kinase C: a regulator of cytoskeleton remodelling and T-cell migration.Selective protein kinase Cθ (PKCθ) inhibitors for the treatment of autoimmune diseases.Duplicity of protein kinase C-θ: Novel insights into human T-cell biology.PKCα and PKCβ cooperate functionally in CD3-induced de novo IL-2 mRNA transcription.
P2860
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P2860
Resistance to experimental autoimmune encephalomyelitis and impaired IL-17 production in protein kinase C theta-deficient mice
description
2006 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im März 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/03/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/03/01)
@nl
наукова стаття, опублікована в березні 2006
@uk
مقالة علمية (نشرت في مارس 2006)
@ar
name
Resistance to experimental aut ...... kinase C theta-deficient mice
@ast
Resistance to experimental aut ...... kinase C theta-deficient mice
@en
Resistance to experimental aut ...... kinase C theta-deficient mice
@nl
type
label
Resistance to experimental aut ...... kinase C theta-deficient mice
@ast
Resistance to experimental aut ...... kinase C theta-deficient mice
@en
Resistance to experimental aut ...... kinase C theta-deficient mice
@nl
prefLabel
Resistance to experimental aut ...... kinase C theta-deficient mice
@ast
Resistance to experimental aut ...... kinase C theta-deficient mice
@en
Resistance to experimental aut ...... kinase C theta-deficient mice
@nl
P2093
P3181
P1476
Resistance to experimental aut ...... kinase C theta-deficient mice
@en
P2093
Deena L. Hepburn
Jingyong Zhao
Jonathon D. Sedgwick
Seng-Lai Tan
Songqing Na
Subba R. Chintalacharuvu
Xinyi Cynthia Chen
P304
P3181
P356
10.4049/JIMMUNOL.176.5.2872
P407
P577
2006-03-01T00:00:00Z