Maternal IL-11Ralpha function is required for normal decidua and fetoplacental development in mice
about
Expression and function of interleukin-11 and its receptor alpha in the human endometriumIL-11 and IL-11Ralpha immunolocalisation at primate implantation sites supports a role for IL-11 in placentation and fetal developmentUterine extracellular matrix components are altered during defective decidualization in interleukin-11 receptor alpha deficient miceThe decidua-the maternal bed embracing the embryo-maintains the pregnancyInterleukin-11 signals through the formation of a hexameric receptor complexESkine, a novel beta-chemokine, is differentially spliced to produce secretable and nuclear targeted isoformsLocalization of pro-inflammatory (IL-12, IL-15) and anti-inflammatory (IL-11, IL-13) cytokines at the foetomaternal interface during murine pregnancyCyclo-oxygenase-2-derived prostacyclin mediates embryo implantation in the mouse via PPARdeltaMaternal Tgif is required for vascularization of the embryonic placentaFKBP52 deficiency-conferred uterine progesterone resistance is genetic background and pregnancy stage specificProkineticin-1 (PROK1) modulates interleukin (IL)-11 expression via prokineticin receptor 1 (PROKR1) and the calcineurin/NFAT signalling pathway.Uterine disorders and pregnancy complications: insights from mouse modelsInterleukin 11 inhibits human trophoblast invasion indicating a likely role in the decidual restraint of trophoblast invasion during placentation.IL11 antagonist inhibits uterine stromal differentiation, causing pregnancy failure in mice.Pregnant rat uterus expresses high levels of the type 3 iodothyronine deiodinaseReceptor recognition by gp130 cytokines.Uterine Rbpj is required for embryonic-uterine orientation and decidual remodeling via Notch pathway-independent and -dependent mechanisms.Endometrial decidualization: of mice and menAP-1 transcription factors, mucin-type molecules and MMPs regulate the IL-11 mediated invasiveness of JEG-3 and HTR-8/SVneo trophoblastic cellsSubfertility linked to combined luteal insufficiency and uterine progesterone resistance.Physiological and molecular determinants of embryo implantationUterine NK cells are critical in shaping DC immunogenic functions compatible with pregnancy progression.Developmental regulation of decidual cell polyploidy at the site of implantationContraceptive vaccines targeting factors involved in establishment of pregnancy.Proteomic analysis identifies interleukin 11 regulated plasma membrane proteins in human endometrial epithelial cells in vitro.The production of interleukin-11 and decidualization are compromised in endometrial stromal cells derived from patients with infertility.Functional characterization of W147A: a high-affinity interleukin-11 antagonistCytokines: Important for implantation?Defective gp130-mediated signal transducer and activator of transcription (STAT) signaling results in degenerative joint disease, gastrointestinal ulceration, and failure of uterine implantationImmunolocalisation of phosphorylated STAT3, interleukin 11 and leukaemia inhibitory factor in endometrium of women with unexplained infertility during the implantation window.Regulation of human endometrial stromal proliferation and differentiation by C/EBPβ involves cyclin E-cdk2 and STAT3.The role of endometrium in endometriosis.Uterine DCs are essential for pregnancyUterine deletion of Gp130 or Stat3 shows implantation failure with increased estrogenic responses.Alkaline phosphatases contribute to uterine receptivity, implantation, decidualization, and defense against bacterial endotoxin in hamsters.Progesterone-mediated immunomodulation in pregnancy: its relevance to leukocyte immunotherapy of recurrent miscarriage.Understanding the link between the IL-6 cytokine family and pregnancy: implications for future therapeutics.Cytokines and Blastocyst Hatching.Expression of leukemia inhibitory factor receptor and gp130 in mouse uterus during early pregnancy.Identification of the leukemia inhibitory factor cell targets within the rat testis.
P2860
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P2860
Maternal IL-11Ralpha function is required for normal decidua and fetoplacental development in mice
description
1998 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1998
@ast
im Juli 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998/07/15)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/07/15)
@nl
наукова стаття, опублікована в липні 1998
@uk
مقالة علمية (نشرت في 15-7-1998)
@ar
name
Maternal IL-11Ralpha function ...... oplacental development in mice
@ast
Maternal IL-11Ralpha function ...... oplacental development in mice
@en
Maternal IL-11Ralpha function ...... oplacental development in mice
@nl
type
label
Maternal IL-11Ralpha function ...... oplacental development in mice
@ast
Maternal IL-11Ralpha function ...... oplacental development in mice
@en
Maternal IL-11Ralpha function ...... oplacental development in mice
@nl
prefLabel
Maternal IL-11Ralpha function ...... oplacental development in mice
@ast
Maternal IL-11Ralpha function ...... oplacental development in mice
@en
Maternal IL-11Ralpha function ...... oplacental development in mice
@nl
P2093
P2860
P3181
P356
P1433
P1476
Maternal IL-11Ralpha function ...... oplacental development in mice
@en
P2093
A. Gossler
D. Roopenian
P. Bilinski
P2860
P304
P3181
P356
10.1101/GAD.12.14.2234
P577
1998-07-15T00:00:00Z