An essential role of Bmp4 in the atrioventricular septation of the mouse heart
about
MEGF8 is a modifier of BMP signaling in trigeminal sensory neuronsTranscription factor genes Smad4 and Gata4 cooperatively regulate cardiac valve development. [corrected]Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation.VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5Inactivation of the Sema5a gene results in embryonic lethality and defective remodeling of the cranial vascular systemThe matricellular protein CCN1 is essential for cardiac developmentTargeting BMP signalling in cardiovascular disease and anaemiaProgramming and reprogramming a human heart cellEndocardial and epicardial epithelial to mesenchymal transitions in heart development and diseaseIncomplete penetrance and phenotypic variability characterize Gdf6-attributable oculo-skeletal phenotypesRegulation of heart valve morphogenesis by Eph receptor ligand, ephrin-A1Bmp4 signaling is required for outflow-tract septation and branchial-arch artery remodelingDifferential expression and function of Tbx5 and Tbx20 in cardiac developmentTbx5-hedgehog molecular networks are essential in the second heart field for atrial septationBmp4 is required for tracheal formation: a novel mouse model for tracheal agenesisBMP type II receptor regulates positioning of outflow tract and remodeling of atrioventricular cushion during cardiogenesisInteraction of Gata4 and Gata6 with Tbx5 is critical for normal cardiac developmentBMP4 is required in the anterior heart field and its derivatives for endocardial cushion remodeling, outflow tract septation, and semilunar valve developmentOutflow tract cushions perform a critical valve-like function in the early embryonic heart requiring BMPRIA-mediated signaling in cardiac neural crest2,3,7,8-Tetrachlorodibenzo-p-dioxin exposure prevents cardiac valve formation in developing zebrafishHeart-specific deletion of CnB1 reveals multiple mechanisms whereby calcineurin regulates cardiac growth and function.BMP signals promote proepicardial protrusion necessary for recruitment of coronary vessel and epicardial progenitors to the heartCritical roles of miRNA-mediated regulation of TGFβ signalling during mouse cardiogenesis.Non-CpG methylation by DNMT3B facilitates REST binding and gene silencing in developing mouse heartsInducible cardiomyocyte-specific gene disruption directed by the rat Tnnt2 promoter in the mouseZebrafish Crip2 plays a critical role in atrioventricular valve development by downregulating the expression of ECM genes in the endocardial cushion.Embryonic Development of the Bicuspid Aortic Valve.Bmp2 and Bmp4 genetically interact to support multiple aspects of mouse development including functional heart development.Development of a unique system for spatiotemporal and lineage-specific gene expression in mice.BMP signaling controls formation of a primordial germ cell niche within the early genital ridges.Genetic interaction between Bmp2 and Bmp4 reveals shared functions during multiple aspects of mouse organogenesis.BMPER-induced BMP signaling promotes coronary artery remodeling.Myocardial smad4 is essential for cardiogenesis in mouse embryos.Complex cardiac Nkx2-5 gene expression activated by noggin-sensitive enhancers followed by chamber-specific modulesDisruption of myocardial Gata4 and Tbx5 results in defects in cardiomyocyte proliferation and atrioventricular septation.Myocardial deletion of Smad4 using a novel α skeletal muscle actin Cre recombinase transgenic mouse causes misalignment of the cardiac outflow tractThe complex SNP and CNV genetic architecture of the increased risk of congenital heart defects in Down syndrome.Cell autonomous requirement of endocardial Smad4 during atrioventricular cushion development in mouse embryosBone Morphogenetic Protein (BMP) signaling in development and human diseasesKMT2D regulates specific programs in heart development via histone H3 lysine 4 di-methylation.
P2860
Q21128782-0CE205F4-B14D-4DB9-A9FC-0DD2BD256AB9Q24293493-46C41018-DFFE-4CD0-90D8-644461036040Q24301606-8F172689-F5D4-4D74-AA7B-3EF77B782CADQ24318787-3C5D11C6-61F8-46C2-97C1-5CEA047238E4Q24519075-2789F511-0BBE-4E31-BC5C-AE07F3615E70Q24678075-3C2EEED7-3E91-4A06-94F1-5C1E683F79E7Q26783734-935035B7-CF23-485D-A8AB-893095E65FC3Q26823933-BD2EF38E-854A-46F2-8821-FF2862A47BCFQ26830155-8DA7F0DB-BBC5-4F23-A741-44866B0BE24BQ28306123-031C21DA-FE9F-4E32-9DB7-B8BEE9B26D1AQ28504714-BDAA44D0-E404-4CC4-A696-B6905B60857EQ28507815-410EE309-4F8D-448D-9171-B477E7BCCA3EQ28508533-00DA8342-0057-4B8B-98D7-E7F65301B273Q28509085-B7A9A67B-ED8F-4218-A0A2-7D77126D3E37Q28510349-81C1AE8C-4187-4E08-8945-A730AD077788Q28512717-66439A8C-F152-4C99-A115-F505AC34B37DQ28594374-A1FE57F8-3B8F-45B6-A042-8EA3715968B2Q28594976-31821355-4A22-4EC2-84E6-4B04653C9146Q30478829-00C8423C-C38A-405C-ACD1-F37255212416Q30482701-0E2DFAA2-9F06-45A1-8135-87F3025C9952Q30493276-FD77BD51-00E6-45A3-94FA-A934C5CE10F1Q30496194-CB6D6272-80E8-4ACD-90C9-B79C95FFE97CQ31813050-220F18E7-A6D1-44A7-AD12-14793DE8C6B8Q33557670-4CD97322-2B81-4A46-84E1-3AD0C0B66281Q33590571-D92FE738-0A47-4D6B-B21F-2727D1B1BFF4Q33707981-BC00FE4D-410D-4E52-A09A-BC7C8A5A82F9Q33708015-490B329D-D08A-4DB2-951E-67C85C6C6CA0Q33761311-C2D34908-2DBC-4D37-B0F0-2B6E5B805975Q33853864-784DD058-3F99-477D-8414-0C2A877CA3FFQ33912406-6E94071A-F9E3-4FCC-9955-06206D149ED2Q33938401-155D8D74-322D-4B74-A0B8-4D5A291F5BE8Q33954831-727E17D1-0884-4FDA-B0D9-F211EF7887ECQ34009514-3931E4E1-3725-4800-8163-1DA3A5FFEC82Q34015900-6A237715-8303-4E6C-9188-AA7851E91875Q34155354-2DD70836-2718-430F-B784-6BC055F87275Q34156745-5CBF2F06-C2AE-414C-AE78-61F15CB34230Q34352054-521C9CE8-B28F-41CD-8A1D-B59BD918C42EQ34490155-F9E3C3DE-7BB2-431B-9263-936DFECBFCB3Q34512444-1AA282BC-9B65-4AAF-8A66-C5EADC02B3A0Q34516463-85C0169B-27A0-4889-9AB1-A7E354DF2EB8
P2860
An essential role of Bmp4 in the atrioventricular septation of the mouse heart
description
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im Oktober 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/10/01)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/10/01)
@nl
наукова стаття, опублікована в жовтні 2003
@uk
مقالة علمية (نشرت في أكتوبر 2003)
@ar
name
An essential role of Bmp4 in the atrioventricular septation of the mouse heart
@ast
An essential role of Bmp4 in the atrioventricular septation of the mouse heart
@en
An essential role of Bmp4 in the atrioventricular septation of the mouse heart
@nl
type
label
An essential role of Bmp4 in the atrioventricular septation of the mouse heart
@ast
An essential role of Bmp4 in the atrioventricular septation of the mouse heart
@en
An essential role of Bmp4 in the atrioventricular septation of the mouse heart
@nl
prefLabel
An essential role of Bmp4 in the atrioventricular septation of the mouse heart
@ast
An essential role of Bmp4 in the atrioventricular septation of the mouse heart
@en
An essential role of Bmp4 in the atrioventricular septation of the mouse heart
@nl
P2093
P2860
P3181
P356
P1433
P1476
An essential role of Bmp4 in the atrioventricular septation of the mouse heart
@en
P2093
Brigid L. M. Hogan
H. Scott Baldwin
Holger Kulessa
Kevin Tompkins
Lorene Batts
Yingna Zhou
P2860
P304
P3181
P356
10.1101/GAD.1124803
P577
2003-10-01T00:00:00Z