CaMKII-mediated phosphorylation of the myosin motor Myo1c is required for insulin-stimulated GLUT4 translocation in adipocytes
about
Integrating the biophysical and molecular mechanisms of auditory hair cell mechanotransductionMotor protein Myo1c is a podocyte protein that facilitates the transport of slit diaphragm protein Neph1 to the podocyte membraneSialic acid modification of adiponectin is not required for multimerization or secretion but determines half-life in circulationDifferential 14-3-3 affinity capture reveals new downstream targets of phosphatidylinositol 3-kinase signalingControl of the initiation and termination of kinesin-1-driven transport by myosin-Ic and nonmuscle tropomyosinForce Generation by Membrane-Associated Myosin-I.Myo1c binding to submembrane actin mediates insulin-induced tethering of GLUT4 vesiclesModification of loop 1 affects the nucleotide binding properties of Myo1c, the adaptation motor in the inner earAS160 phosphotyrosine-binding domain constructs inhibit insulin-stimulated GLUT4 vesicle fusion with the plasma membraneIdentification of a distal GLUT4 trafficking event controlled by actin polymerizationMyo1c regulates lipid raft recycling to control cell spreading, migration and Salmonella invasionTropomodulin3 is a novel Akt2 effector regulating insulin-stimulated GLUT4 exocytosis through cortical actin remodeling.Structural Analysis of the Myo1c and Neph1 Complex Provides Insight into the Intracellular Movement of Neph1Mitochondrial dysfunction has divergent, cell type-dependent effects on insulin actionCaMKII regulates contraction- but not insulin-induced glucose uptake in mouse skeletal muscle.Identification of three distinct functional sites of insulin-mediated GLUT4 trafficking in adipocytes using quantitative single molecule imaging.Specific nuclear localizing sequence directs two myosin isoforms to the cell nucleus in calmodulin-sensitive manner.Telmisartan improves insulin resistance of skeletal muscle through peroxisome proliferator-activated receptor-δ activation.Myo1c regulates glucose uptake in mouse skeletal muscle.Signaling, cytoskeletal and membrane mechanisms regulating GLUT4 exocytosis.An analysis of DNA methylation in human adipose tissue reveals differential modification of obesity genes before and after gastric bypass and weight loss.Regulation of myosin light chain kinase during insulin-stimulated glucose uptake in 3T3-L1 adipocytesEffects of GLUT4 expression on insulin resistance in patients with advanced liver cirrhosis.GLUT4 exocytosis.Analysis of an independent tumor suppressor locus telomeric to Tp53 suggested Inpp5k and Myo1c as novel tumor suppressor gene candidates in this region.Endoproteolytic cleavage of TUG protein regulates GLUT4 glucose transporter translocationMyo1c facilitates G-actin transport to the leading edge of migrating endothelial cellsAnalysis of the Human Proteome in Subcutaneous and Visceral Fat Depots in Diabetic and Non-diabetic Patients with Morbid ObesityLowered Expression of Tumor Suppressor Candidate MYO1C Stimulates Cell Proliferation, Suppresses Cell Adhesion and Activates AKT.Myosin-I molecular motors at a glanceMapping insulin/GLUT4 circuitry.Functional roles for myosin 1c in cellular signaling pathways.Regulation and control of myosin-I by the motor and light chain-binding domains.Signal transduction meets vesicle traffic: the software and hardware of GLUT4 translocation.Rho GTPases in insulin-stimulated glucose uptake.Molecular mechanisms for the regulation of insulin-stimulated glucose uptake by small guanosine triphosphatases in skeletal muscle and adipocytes.Role of mitochondrial dysfunction and dysregulation of Ca(2+) homeostasis in insulin insensitivity of mammalian cells.The CLASP2 Protein Interaction Network in Adipocytes Links CLIP2 to AGAP3, CLASP2 to G2L1, MARK2, and SOGA1, and Identifies SOGA1 as a Microtubule-Associated Protein.Visualization and biochemical analyses of the emerging mammalian 14-3-3-phosphoproteome.Bioinformatic and experimental survey of 14-3-3-binding sites.
P2860
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P2860
CaMKII-mediated phosphorylation of the myosin motor Myo1c is required for insulin-stimulated GLUT4 translocation in adipocytes
description
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im November 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/11/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/11/01)
@nl
наукова стаття, опублікована в листопаді 2008
@uk
مقالة علمية (نشرت في نوفمبر 2008)
@ar
name
CaMKII-mediated phosphorylatio ...... T4 translocation in adipocytes
@ast
CaMKII-mediated phosphorylatio ...... T4 translocation in adipocytes
@en
CaMKII-mediated phosphorylatio ...... T4 translocation in adipocytes
@nl
type
label
CaMKII-mediated phosphorylatio ...... T4 translocation in adipocytes
@ast
CaMKII-mediated phosphorylatio ...... T4 translocation in adipocytes
@en
CaMKII-mediated phosphorylatio ...... T4 translocation in adipocytes
@nl
prefLabel
CaMKII-mediated phosphorylatio ...... T4 translocation in adipocytes
@ast
CaMKII-mediated phosphorylatio ...... T4 translocation in adipocytes
@en
CaMKII-mediated phosphorylatio ...... T4 translocation in adipocytes
@nl
P2093
P50
P3181
P1433
P1476
CaMKII-mediated phosphorylatio ...... T4 translocation in adipocytes
@en
P2093
Mark C Wagner
Mark Larance
Michael Guilhaus
Ming Fai Yip
P304
P3181
P356
10.1016/J.CMET.2008.09.011
P577
2008-11-01T00:00:00Z