Acyl-CoA synthetase activity links wild-type but not mutant alpha-synuclein to brain arachidonate metabolism
about
Alpha-synuclein and polyunsaturated fatty acids promote clathrin-mediated endocytosis and synaptic vesicle recyclingAlpha-synuclein sequesters arachidonic acid to modulate SNARE-mediated exocytosisRat brain docosahexaenoic acid metabolism is not altered by a 6-day intracerebral ventricular infusion of bacterial lipopolysaccharide.Catalytic function of PLA2G6 is impaired by mutations associated with infantile neuroaxonal dystrophy but not dystonia-parkinsonismLipid classes and fatty acid patterns are altered in the brain of γ-synuclein null mutant mice.Mode of action of mood stabilizers: is the arachidonic acid cascade a common target?Alpha-synuclein function and dysfunction on cellular membranes.Neuroinflammation and J2 prostaglandins: linking impairment of the ubiquitin-proteasome pathway and mitochondria to neurodegeneration.Expression of mutant alpha-synuclein modulates microglial phenotype in vitroiPLA2β knockout mouse, a genetic model for progressive human motor disorders, develops age-related neuropathology.A rapid oxygen exchange on prostaglandins in plasma represents plasma esterase activity that is inhibited by diethylumbelliferyl phosphate with high affinity.The influence of N-terminal acetylation on micelle-induced conformational changes and aggregation of α-Synuclein.Brain prostaglandin formation is increased by alpha-synuclein gene-ablation during global ischemia.alpha-Synuclein: a therapeutic target for Parkinson's disease?Lipopolysaccharide-induced blood brain barrier permeability is enhanced by alpha-synuclein expressionLipidomic profiling in mouse brain reveals differences between ages and genders, with smaller changes associated with alpha-synuclein genotype.Reversibility of neuropathology in Tay-Sachs-related diseases.Lipid dysfunction and pathogenesis of multiple system atrophy.The function of α-synuclein.Acyl-CoA metabolism and partitioning.Mechanisms of alpha-synuclein action on neurotransmission: cell-autonomous and non-cell autonomous roleLooking at the recent advances in understanding α-synuclein and its aggregation through the proteoform prism.Structural and morphological characterization of aggregated species of α-synuclein induced by docosahexaenoic acid.FABP3 protein promotes α-synuclein oligomerization associated with 1-methyl-1,2,3,6-tetrahydropiridine-induced neurotoxicity.Diacylglycerol kinase ε localizes to subsurface cisterns of cerebellar Purkinje cells.Blood-brain barrier and brain fatty acid uptake: Role of arachidonic acid and PGE2.
P2860
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P2860
Acyl-CoA synthetase activity links wild-type but not mutant alpha-synuclein to brain arachidonate metabolism
description
2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im Juni 2006 veröffentlicher wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/06/06)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/06/06)
@nl
наукова стаття, опублікована в червні 2006
@uk
مقالة علمية نشرت في 6-6-2006 حول موضوع: دماغ
@ar
name
Acyl-CoA synthetase activity l ...... brain arachidonate metabolism
@ast
Acyl-CoA synthetase activity l ...... brain arachidonate metabolism
@en
Acyl-CoA synthetase activity l ...... brain arachidonate metabolism
@nl
type
label
Acyl-CoA synthetase activity l ...... brain arachidonate metabolism
@ast
Acyl-CoA synthetase activity l ...... brain arachidonate metabolism
@en
Acyl-CoA synthetase activity l ...... brain arachidonate metabolism
@nl
prefLabel
Acyl-CoA synthetase activity l ...... brain arachidonate metabolism
@ast
Acyl-CoA synthetase activity l ...... brain arachidonate metabolism
@en
Acyl-CoA synthetase activity l ...... brain arachidonate metabolism
@nl
P2093
P2860
P921
P356
P1433
P1476
Acyl-CoA synthetase activity l ...... brain arachidonate metabolism
@en
P2093
Eric J Murphy
Ingrid Pribill
Mikhail Y Golovko
Nelson B Cole
Nils J Faergeman
Robert L Nussbaum
Thad A Rosenberger
P2860
P304
P356
10.1021/BI0600289
P407
P577
2006-06-01T00:00:00Z