about
Gpr126 is essential for peripheral nerve development and myelination in mammalsAntibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan's syndrome and acquired neuromyotoniaLGI proteins in the nervous system.ADAM22, a Kv1 channel-interacting protein, recruits membrane-associated guanylate kinases to juxtaparanodes of myelinated axonsAdam22 is a major neuronal receptor for Lgi4-mediated Schwann cell signalingLgi4 promotes the proliferation and differentiation of glial lineage cells throughout the developing peripheral nervous systemConservation and divergence of ADAM family proteins in the Xenopus genome.Loss of zebrafish lgi1b leads to hydrocephalus and sensitization to pentylenetetrazol induced seizure-like behavior.The temporal and spatial expression pattern of the LGI1 epilepsy predisposition gene during mouse embryonic cranial development.Electroclinical characterization of epileptic seizures in leucine-rich, glioma-inactivated 1-deficient mice.Disruption of LGI1-linked synaptic complex causes abnormal synaptic transmission and epilepsy.Inactivation of LGI1 expression accompanies early stage hyperplasia of prostate epithelium in the TRAMP murine model of prostate cancer.Similarity of molecular phenotype between known epilepsy gene LGI1 and disease candidate gene LGI2.Lgi1 null mutant mice exhibit myoclonic seizures and CA1 neuronal hyperexcitabilityA computational model of the LGI1 protein suggests a common binding site for ADAM proteins.LGI2 truncation causes a remitting focal epilepsy in dogs.Investigation of LGI1 as the antigen in limbic encephalitis previously attributed to potassium channels: a case seriesComposition, assembly, and maintenance of excitable membrane domains in myelinated axons.Essential roles of leucine-rich glioma inactivated 1 in the development of embryonic and postnatal cerebellum.Identification of a common risk haplotype for canine idiopathic epilepsy in the ADAM23 gene.Domain-dependent clustering and genotype-phenotype analysis of LGI1 mutations in ADPEAFThe LGI1-ADAM22 protein complex directs synapse maturation through regulation of PSD-95 functionSelective Loss of Presynaptic Potassium Channel Clusters at the Cerebellar Basket Cell Terminal Pinceau in Adam11 Mutants Reveals Their Role in Ephaptic Control of Purkinje Cell Firing.ADAM23, a Gene Related to LGI1, Is Not Linked to Autosomal Dominant Lateral Temporal Epilepsy.ADAM23 is a common risk gene for canine idiopathic epilepsy.LGI1 acts presynaptically to regulate excitatory synaptic transmission during early postnatal development.LGI Proteins and Epilepsy in Human and AnimalsStructural characterization of the ectodomain of a disintegrin and metalloproteinase-22 (ADAM22), a neural adhesion receptor instead of metalloproteinase: insights on ADAM functionHomozygous inactivation of the LGI1 gene results in hypomyelination in the peripheral and central nervous systems.Signals to promote myelin formation and repair.LGI1 tunes intrinsic excitability by regulating the density of axonal Kv1 channels.Arrested glutamatergic synapse development in human partial epilepsy.ADAM23 promotes neuronal differentiation of human neural progenitor cells.LGI1-associated epilepsy through altered ADAM23-dependent neuronal morphologyLoss-of-Function Mutations in LGI4, a Secreted Ligand Involved in Schwann Cell Myelination, Are Responsible for Arthrogryposis Multiplex Congenita.LGI1 binds ADAM11LGI4 binds ADAM22;23;11Structural basis of epilepsy-related ligand-receptor complex LGI1-ADAM22.The Nogo Receptor Ligand LGI1 Regulates Synapse Number and Synaptic Activity in Hippocampal and Cortical Neurons
P2860
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P2860
description
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im Oktober 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/01/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/01/01)
@nl
наукова стаття, опублікована в січні 2008
@uk
مقالة علمية (نشرت عام 2008)
@ar
name
LGI1 and LGI4 bind to ADAM22, ADAM23 and ADAM11
@ast
LGI1 and LGI4 bind to ADAM22, ADAM23 and ADAM11
@en
LGI1 and LGI4 bind to ADAM22, ADAM23 and ADAM11
@nl
type
label
LGI1 and LGI4 bind to ADAM22, ADAM23 and ADAM11
@ast
LGI1 and LGI4 bind to ADAM22, ADAM23 and ADAM11
@en
LGI1 and LGI4 bind to ADAM22, ADAM23 and ADAM11
@nl
prefLabel
LGI1 and LGI4 bind to ADAM22, ADAM23 and ADAM11
@ast
LGI1 and LGI4 bind to ADAM22, ADAM23 and ADAM11
@en
LGI1 and LGI4 bind to ADAM22, ADAM23 and ADAM11
@nl
P2860
P356
P1476
LGI1 and LGI4 bind to ADAM22, ADAM23 and ADAM11
@en
P2093
Hachiro Sugimoto
Yasushi Ishihama
P2860
P304
P356
10.7150/IJBS.4.387
P407
P50
P577
2008-10-21T00:00:00Z