Cloning of mammalian Ire1 reveals diversity in the ER stress responses - Wikidata - awgldk - TriplyDB

Cloning of mammalian Ire1 reveals diversity in the ER stress responses

Cloning of mammalian Ire1 reveals diversity in the ER stress responses

http://www.wikidata.org/entity/Q28587224

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Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress Pancreatic eukaryotic initiation factor-2alpha kinase (PEK) homologues in humans, Drosophila melanogaster and Caenorhabditis elegans that mediate translational control in response to endoplasmic reticulum stress ATF6 as a transcription activator of the endoplasmic reticulum stress element: thapsigargin stress-induced changes and synergistic interactions with NF-Y and YY1 Identification of a novel thioredoxin-related transmembrane protein Identification of the G13 (cAMP-response-element-binding protein-related protein) gene product related to activating transcription factor 6 as a transcriptional activator of the mammalian unfolded protein response Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress Dimerization and release of molecular chaperone inhibition facilitate activation of eukaryotic initiation factor-2 kinase in response to endoplasmic reticulum stress Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha.Human HRD1 protects against ER stress-induced apoptosis through ER-associated degradation Spatial regulation of Raf kinase signaling by RKTG Activation of hepatitis B virus S promoter by a cell type-restricted IRE1-dependent pathway induced by endoplasmic reticulum stress Basis for regulated RNA cleavage by functional analysis of RNase L and Ire1p BRCA1 and BRCA2 as molecular targets for phytochemicals indole-3-carbinol and genistein in breast and prostate cancer cells IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response Japanese encephalitis virus infection initiates endoplasmic reticulum stress and an unfolded protein response Gcn4p and novel upstream activating sequences regulate targets of the unfolded protein response Genome-scale approaches for discovering novel nonconventional splicing substrates of the Ire1 nuclease Genetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in C. elegans.The unfolded protein response: the dawn of a new field Endoplasmic Reticulum Stress Signaling in Plant Immunity--At the Crossroad of Life and Death The unfolded protein response in neurodegenerative diseases: a neuropathological perspective Innate immunity at mucosal surfaces: the IRE1-RIDD-RIG-I pathway Role of endoplasmic reticulum stress and autophagy as interlinking pathways in the pathogenesis of inflammatory bowel disease The unfolded protein response in retinal vascular diseases: implications and therapeutic potential beyond protein folding Drosophila as a model for unfolded protein response research The unfolded protein response and diabetic retinopathy Endoplasmic reticulum stress and diabetic cardiomyopathy Flavivirus Infection Activates the XBP1 Pathway of the Unfolded Protein Response To Cope with Endoplasmic Reticulum Stress Structure and mechanism of action of the hydroxy–aryl–aldehyde class of IRE1 endoribonuclease inhibitors Flavonol Activation Defines an Unanticipated Ligand-Binding Site in the Kinase-RNase Domain of IRE1 ER stress and apoptosis: a new mechanism for retinal cell death.The transcriptional co-activator ADA5 is required for HAC1 mRNA processing in vivo.Genetic evidence for a role of BiP/Kar2 that regulates Ire1 in response to accumulation of unfolded proteins.An essential dimer-forming subregion of the endoplasmic reticulum stress sensor Ire1.PERK mediates cell-cycle exit during the mammalian unfolded protein response The protein kinase/endoribonuclease IRE1alpha that signals the unfolded protein response has a luminal N-terminal ligand-independent dimerization domain Salicylates trigger protein synthesis inhibition in a protein kinase R-like endoplasmic reticulum kinase-dependent manner The exosome complex establishes a barricade to erythroid maturation

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P2860

Cloning of mammalian Ire1 reveals diversity in the ER stress responses

http://www.wikidata.org/entity/Q28587224

description

1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

artículu científicu espublizáu en 1998

@ast

im Oktober 1998 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 1998/10/01)

@sk

vědecký článek publikovaný v roce 1998

@cs

wetenschappelijk artikel (gepubliceerd op 1998/10/01)

@nl

наукова стаття, опублікована в жовтні 1998

@uk

مقالة علمية (نشرت في أكتوبر 1998)

@ar

name

Cloning of mammalian Ire1 reveals diversity in the ER stress responses

@ast

Cloning of mammalian Ire1 reveals diversity in the ER stress responses

@en

Cloning of mammalian Ire1 reveals diversity in the ER stress responses

@nl

type

label

Cloning of mammalian Ire1 reveals diversity in the ER stress responses

@ast

Cloning of mammalian Ire1 reveals diversity in the ER stress responses

@en

Cloning of mammalian Ire1 reveals diversity in the ER stress responses

@nl

prefLabel

Cloning of mammalian Ire1 reveals diversity in the ER stress responses

@ast

Cloning of mammalian Ire1 reveals diversity in the ER stress responses

@en

Cloning of mammalian Ire1 reveals diversity in the ER stress responses

@nl

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The EMBO Journal

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Cloning of mammalian Ire1 reveals diversity in the ER stress responses

@en

P2093

E. M. Jolicoeur

http://www.w3.org/2001/XMLSchema#string

H. P. Harding

http://www.w3.org/2001/XMLSchema#string

M. Kuroda

http://www.w3.org/2001/XMLSchema#string

X. Z. Wang

http://www.w3.org/2001/XMLSchema#string

Y. Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma

Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma

A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells

Identification of novel stress-induced genes downstream of chop

Molecular cloning of a human cDNA encoding a novel protein, DAD1, whose defect causes apoptotic cell death in hamster BHK21 cells

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product

The essential OST2 gene encodes the 16-kD subunit of the yeast oligosaccharyltransferase, a highly conserved protein expressed in diverse eukaryotic organisms

A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus.

The subnuclear localization of tRNA ligase in yeast.

Protein serine/threonine phosphatase Ptc2p negatively regulates the unfolded-protein response by dephosphorylating Ire1p kinase.

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5708–5717

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1045842

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10.1093/EMBOJ/17.19.5708

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19

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17

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1998-10-01T00:00:00Z

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13531168

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9755171

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1170899

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