Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin
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Autocrine WNT signaling contributes to breast cancer cell proliferation via the canonical WNT pathway and EGFR transactivationCasein kinase 1 delta functions at the centrosome to mediate Wnt-3a-dependent neurite outgrowthWnt5a signaling induces proliferation and survival of endothelial cells in vitro and expression of MMP-1 and Tie-2Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expressionConstitutive activation of the Wnt canonical pathway in mantle cell lymphomaInhibition of the Wnt/beta-catenin pathway by the WWOX tumor suppressor proteinZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive mannerCaSR stimulates secretion of Wnt5a from colonic myofibroblasts to stimulate CDX2 and sucrase-isomaltase using Ror2 on intestinal epitheliaDisruption of Wnt/β-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human CellsItch is required for lateral line development in zebrafishAutonomous regulation of osteosarcoma cell invasiveness by Wnt5a/Ror2 signalingAntitumorigenic effect of Wnt 7a and Fzd 9 in non-small cell lung cancer cells is mediated through ERK-5-dependent activation of peroxisome proliferator-activated receptor gammaAnalysis of combinatorial effects of Wnts and Frizzleds on beta-catenin/armadillo stabilization and Dishevelled phosphorylationWNT5A encodes two isoforms with distinct functions in cancersBoth canonical and non-canonical Wnt signaling independently promote stem cell growth in mammospheresThe extracellular domain of Lrp5/6 inhibits noncanonical Wnt signaling in vivoAbelson family kinases regulate Frizzled planar cell polarity signaling via Dsh phosphorylationDose-dependent effect of estrogen suppresses the osteo-adipogenic transdifferentiation of osteoblasts via canonical Wnt signaling pathway.An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/wingless signaling pathway.Breast cancer-specific mutations in CK1epsilon inhibit Wnt/beta-catenin and activate the Wnt/Rac1/JNK and NFAT pathways to decrease cell adhesion and promote cell migration.Functional analysis of dishevelled-3 phosphorylation identifies distinct mechanisms driven by casein kinase 1ϵ and frizzled5.Null and hypomorph Prickle1 alleles in mice phenocopy human Robinow syndrome and disrupt signaling downstream of Wnt5aCanonical and noncanonical Wnts use a common mechanism to activate completely unrelated coreceptors.Dvl2-dependent activation of Daam1 and RhoA regulates Wnt5a-induced breast cancer cell migration.Dishevelled proteins are associated with olfactory sensory neuron presynaptic terminalsSequential activation and inactivation of Dishevelled in the Wnt/beta-catenin pathway by casein kinases.HMGB factors are required for posterior digit development through integrating signaling pathway activitiesWnt signaling in liver cancer.Wnt ligand-dependent activation of the negative feedback regulator Nkd1.Beta-arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo.Wnt5a-Ror-Dishevelled signaling constitutes a core developmental pathway that controls tissue morphogenesisBoth LRP5 and LRP6 receptors are required to respond to physiological Wnt ligands in mammary epithelial cells and fibroblasts.Wnt5a Signals through DVL1 to Repress Ribosomal DNA Transcription by RNA Polymerase I.Cdc42 and noncanonical Wnt signal transduction pathways cooperate to promote cell polarity.Wnt-frizzled signaling is part of an FGF-induced cascade that promotes lens fiber differentiation.The E3 ubiquitin ligase ITCH negatively regulates canonical Wnt signaling by targeting dishevelled protein.Age-related neuroinflammation and changes in AKT-GSK-3β and WNT/ β-CATENIN signaling in rat hippocampus.Homozygous deletion of glycogen synthase kinase 3beta bypasses senescence allowing Ras transformation of primary murine fibroblastsFunctional consequences of Wnt-induced dishevelled 2 phosphorylation in canonical and noncanonical Wnt signaling.The Intracellular Loop 2 F328S Frizzled-4 Mutation Implicated in Familial Exudative Vitreoretinopathy Impairs Dishevelled Recruitment.
P2860
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P248
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P2860
Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin
description
2004 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Juni 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/06/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/06/01)
@nl
наукова стаття, опублікована в червні 2004
@uk
مقالة علمية (نشرت في يونيو 2004)
@ar
name
Wnt proteins induce dishevelle ...... lity to stabilize beta-catenin
@ast
Wnt proteins induce dishevelle ...... lity to stabilize beta-catenin
@en
Wnt proteins induce dishevelle ...... lity to stabilize beta-catenin
@nl
type
label
Wnt proteins induce dishevelle ...... lity to stabilize beta-catenin
@ast
Wnt proteins induce dishevelle ...... lity to stabilize beta-catenin
@en
Wnt proteins induce dishevelle ...... lity to stabilize beta-catenin
@nl
prefLabel
Wnt proteins induce dishevelle ...... lity to stabilize beta-catenin
@ast
Wnt proteins induce dishevelle ...... lity to stabilize beta-catenin
@en
Wnt proteins induce dishevelle ...... lity to stabilize beta-catenin
@nl
P2093
P2860
P921
P3181
P1476
Wnt proteins induce dishevelle ...... lity to stabilize beta-catenin
@en
P2093
Anthony M C Brown
Keith R Brennan
Leslie A Castelo-Soccio
P2860
P304
P3181
P356
10.1128/MCB.24.11.4757-4768.2004
P407
P577
2004-06-01T00:00:00Z