PML bodies provide an important platform for the maintenance of telomeric chromatin integrity in embryonic stem cells
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Telomere regulation in pluripotent stem cellsPML is required for telomere stability in non-neoplastic human cellsGenetic Inactivation of ATRX Leads to a Decrease in the Amount of Telomeric Cohesin and Level of Telomere Transcription in Human Glioma CellsPromyelocytic Leukemia Protein Is an Essential Regulator of Stem Cell Pluripotency and Somatic Cell Reprogramming.The PML-associated protein DEK regulates the balance of H3.3 loading on chromatin and is important for telomere integrityHistone variant H3.3 provides the heterochromatic H3 lysine 9 tri-methylation mark at telomeresHIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia.CHK1-driven histone H3.3 serine 31 phosphorylation is important for chromatin maintenance and cell survival in human ALT cancer cells.Dynamic modulation of HSV chromatin drives initiation of infection and provides targets for epigenetic therapies.HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse.Dynamics of histone H3.3 deposition in proliferating and senescent cells reveals a DAXX-dependent targeting to PML-NBs important for pericentromeric heterochromatin organization.Human cytomegalovirus infection of human embryonic stem cell-derived primitive neural stem cells is restricted at several steps but leads to the persistence of viral DNA.The PML-Interacting Protein DAXX: Histone Loading Gets into the Picture.Aging Effects on Cardiac Progenitor Cell Physiology.Emerging roles of ATRX in cancer.PML protein organizes heterochromatin domains where it regulates histone H3.3 deposition by ATRX/DAXX.Histone chaperone HIRA deposits histone H3.3 onto foreign viral DNA and contributes to anti-viral intrinsic immunity.Aurora Kinase B, a novel regulator of TERF1 binding and telomeric integrity.Ribosomal DNA copy loss and repeat instability in ATRX-mutated cancers.ATRX loss induces multiple hallmarks of the alternative lengthening of telomeres (ALT) phenotype in human glioma cell lines in a cell line-specific manner
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P2860
PML bodies provide an important platform for the maintenance of telomeric chromatin integrity in embryonic stem cells
description
2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2013
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im April 2013 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2013/04/01)
@sk
vědecký článek publikovaný v roce 2013
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wetenschappelijk artikel (gepubliceerd op 2013/04/01)
@nl
наукова стаття, опублікована у квітні 2013
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مقالة علمية (نشرت في أبريل 2013)
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name
PML bodies provide an importan ...... egrity in embryonic stem cells
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PML bodies provide an importan ...... egrity in embryonic stem cells
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PML bodies provide an importan ...... egrity in embryonic stem cells
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type
label
PML bodies provide an importan ...... egrity in embryonic stem cells
@ast
PML bodies provide an importan ...... egrity in embryonic stem cells
@en
PML bodies provide an importan ...... egrity in embryonic stem cells
@nl
prefLabel
PML bodies provide an importan ...... egrity in embryonic stem cells
@ast
PML bodies provide an importan ...... egrity in embryonic stem cells
@en
PML bodies provide an importan ...... egrity in embryonic stem cells
@nl
P2093
P2860
P921
P356
P1476
PML bodies provide an importan ...... egrity in embryonic stem cells
@en
P2093
F. Lyn Chan
Fiona T. M. Chang
James D. McGhie
K. H. Andy Choo
Melissa A. Anderson
Michelle C. Tang
P2860
P304
P356
10.1093/NAR/GKT114
P407
P577
2013-04-01T00:00:00Z