Tage4/Nectin-like molecule-5 heterophilically trans-interacts with cell adhesion molecule Nectin-3 and enhances cell migration
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Role of scaffold protein afadin dilute domain-interacting protein (ADIP) in platelet-derived growth factor-induced cell movement by activating Rac protein through Vav2 proteinInvolvement of nectin in inactivation of integrin alpha(v)beta(3) after the establishment of cell-cell adhesionImplications of nectin-like molecule-2/IGSF4/RA175/SgIGSF/TSLC1/SynCAM1 in cell-cell adhesion and transmembrane protein localization in epithelial cellsInteraction of nectin-like molecule 2 with integrin alpha6beta4 and inhibition of disassembly of integrin alpha6beta4 from hemidesmosomesInhibition of cell movement and proliferation by cell-cell contact-induced interaction of Necl-5 with nectin-3Crystal Structure of the cis-Dimer of Nectin-1: IMPLICATIONS FOR THE ARCHITECTURE OF CELL-CELL JUNCTIONSNectin ectodomain structures reveal a canonical adhesive interfaceStructure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clusteringIntegrins in the Spotlight of CancerRecruitment of nectin-3 to cell-cell junctions through trans-heterophilic interaction with CD155, a vitronectin and poliovirus receptor that localizes to alpha(v)beta3 integrin-containing membrane microdomainsThe CD155/poliovirus receptor enhances the proliferation of ras-mutated cellsNecl-5/poliovirus receptor interacts in cis with integrin alphaVbeta3 and regulates its clustering and focal complex formationThe adhesion molecule Necl-3/SynCAM-2 localizes to myelinated axons, binds to oligodendrocytes and promotes cell adhesionCrystal structure of the V domain of human Nectin-like molecule-1/Syncam3/Tsll1/Igsf4b, a neural tissue-specific immunoglobulin-like cell-cell adhesion molecule.Necl-4/SynCAM-4 is expressed in myelinating oligodendrocytes but not required for axonal myelination.The Cell Adhesion Molecule Necl-4/CADM4 Serves as a Novel Regulator for Contact Inhibition of Cell Movement and Proliferation.Nectin-like interactions between poliovirus and its receptor trigger conformational changes associated with cell entry.Roles of nectins in cell adhesion, migration and polarization.Prognostic significance of CD155 mRNA expression in soft tissue sarcomasPaired NK cell receptors controlling NK cytotoxicity.Transcriptional activation of the mouse Necl-5/Tage4/PVR/CD155 gene by fibroblast growth factor or oncogenic Ras through the Raf-MEK-ERK-AP-1 pathway.A mechanically active heterotypic E-cadherin/N-cadherin adhesion enables fibroblasts to drive cancer cell invasion.Cooperative role of nectin-nectin and nectin-afadin interactions in formation of nectin-based cell-cell adhesion.CD155, an onco-immunologic molecule in human tumors.Membrane palmitoylated proteins regulate trafficking and processing of nectins.Silencing of ErbB3/ErbB2 signaling by immunoglobulin-like Necl-2.Roles of Necl-5/poliovirus receptor and Rho-associated kinase (ROCK) in the regulation of transformation of integrin alpha(V)beta(3)-based focal complexes into focal adhesions.Interaction of cancer cells with platelets mediated by Necl-5/poliovirus receptor enhances cancer cell metastasis to the lungs.Regulation of the assembly and adhesion activity of E-cadherin by nectin and afadin for the formation of adherens junctions in Madin-Darby canine kidney cells.Regulation of E-cadherin endocytosis by nectin through afadin, Rap1, and p120ctn.Involvement of heterophilic trans-interaction of Necl-5/Tage4/PVR/CD155 with nectin-3 in formation of nectin- and cadherin-based adherens junctions.Enhancement of serum- and platelet-derived growth factor-induced cell proliferation by Necl-5/Tage4/poliovirus receptor/CD155 through the Ras-Raf-MEK-ERK signaling.Nectin-like molecule-5/Tage4 enhances cell migration in an integrin-dependent, Nectin-3-independent manner.Regulation of platelet-derived growth factor-induced Ras signaling by poliovirus receptor Necl-5 and negative growth regulator Sprouty2.CEACAM2-L on spermatids interacts with poliovirus receptor on Sertoli cells in mouse seminiferous epithelium.Regulation by afadin of cyclical activation and inactivation of Rap1, Rac1, and RhoA small G proteins at leading edges of moving NIH3T3 cells.Interaction of integrin alpha(v)beta3 with nectin. Implication in cross-talk between cell-matrix and cell-cell junctions.Interaction and localization of Necl-5 and PDGF receptor beta at the leading edges of moving NIH3T3 cells: Implications for directional cell movement.Nectin-4 co-stimulates the prolactin receptor by interacting with SOCS1 and inhibiting its activity on the JAK2-STAT5a signaling pathway.Coming of Age: CD96 Emerges as Modulator of Immune Responses.
P2860
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P2860
Tage4/Nectin-like molecule-5 heterophilically trans-interacts with cell adhesion molecule Nectin-3 and enhances cell migration
description
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2003
@ast
im Mai 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/07/25)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/07/25)
@nl
наукова стаття, опублікована в липні 2003
@uk
name
Tage4/Nectin-like molecule-5 h ...... -3 and enhances cell migration
@ast
Tage4/Nectin-like molecule-5 h ...... -3 and enhances cell migration
@en
Tage4/Nectin-like molecule-5 h ...... -3 and enhances cell migration
@nl
type
label
Tage4/Nectin-like molecule-5 h ...... -3 and enhances cell migration
@ast
Tage4/Nectin-like molecule-5 h ...... -3 and enhances cell migration
@en
Tage4/Nectin-like molecule-5 h ...... -3 and enhances cell migration
@nl
prefLabel
Tage4/Nectin-like molecule-5 h ...... -3 and enhances cell migration
@ast
Tage4/Nectin-like molecule-5 h ...... -3 and enhances cell migration
@en
Tage4/Nectin-like molecule-5 h ...... -3 and enhances cell migration
@nl
P2093
P2860
P356
P1476
Tage4/Nectin-like molecule-5 h ...... -3 and enhances cell migration
@en
P2093
Akiko Hamaguchi
Keiko Satoh
Koji Morimoto
Kyoji Takekuni
Masakazu Takeuchi
Shigeki Kakunaga
Shinsuke Itoh
Tatsushi Shingai
Toshio Imai
Yoko Inoue
P2860
P304
28167-28172
P356
10.1074/JBC.M303586200
P407
P50
P577
2003-05-11T00:00:00Z