Glycine N-methyltransferase-/- mice develop chronic hepatitis and glycogen storage disease in the liver
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n-Butylidenephthalide (BP) maintains stem cell pluripotency by activating Jak2/Stat3 pathway and increases the efficiency of iPS cells generationAcetylation of N-terminal valine of glycine N-methyltransferase affects enzyme inhibition by folateGlycine N-Methyltransferase Deficiency: A Member of Dysmethylating Liver Disorders?Genetic polymorphisms of the glycine N-methyltransferase and prostate cancer risk in the health professionals follow-up study.Benzo[a]pyrene effects on glycine N-methyltransferase mRNA expression and enzyme activity in Fundulus heteroclitus embryos.GNMT expression increases hepatic folate contents and folate-dependent methionine synthase-mediated homocysteine remethylation.The biochemical and toxicological significance of hypermethionemia: new insights and clinical relevanceGlycine N-methyltransferase deficiency affects Niemann-Pick type C2 protein stability and regulates hepatic cholesterol homeostasis.Deficiency of glycine N-methyltransferase aggravates atherosclerosis in apolipoprotein E-null mice.NF-E2-related factor 1 (Nrf1) serves as a novel regulator of hepatic lipid metabolism through regulation of the Lipin1 and PGC-1β genesA novel role of the tumor suppressor GNMT in cellular defense against DNA damage.Role of glycine N-methyltransferase in experimental ulcerative colitis.Role of glycine N-methyltransferase in the regulation of T-cell responses in experimental autoimmune encephalomyelitisThe role of genetics in the establishment and maintenance of the epigenome.A novel tumor suppressor function of glycine N-methyltransferase is independent of its catalytic activity but requires nuclear localizationGlycine N-methyltransferase and regulation of S-adenosylmethionine levels.T2DM: Why Epigenetics?The Oncogene PDRG1 Is an Interaction Target of Methionine Adenosyltransferases.Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in micePlasma Glycine and Risk of Acute Myocardial Infarction in Patients With Suspected Stable Angina Pectoris.Effect of transgenic extrahepatic expression of betaine-homocysteine methyltransferase on alcohol or homocysteine-induced fatty liver.Liver carcinogenesis: rodent models of hepatocarcinoma and cholangiocarcinoma.Epigenome-wide DNA methylation analysis implicates neuronal and inflammatory signaling pathways in adult murine hepatic tumorigenesis following perinatal exposure to bisphenol A.Glycine N-methyltransferase deficiency in female mice impairs insulin signaling and promotes gluconeogenesis by modulating the PI3K/Akt pathway in the liverMeta-analysis identifies gene-by-environment interactions as demonstrated in a study of 4,965 mice.Consensus recommendations for the diagnosis, treatment and follow-up of inherited methylation disorders.Experimental mouse models for hepatocellular carcinoma research.Hypermethioninemias of genetic and non-genetic origin: A review.Niemann-Pick type C2 protein regulates liver cancer progression via modulating ERK1/2 pathway: Clinicopathological correlations and therapeutical implications.One-Carbon Metabolism in Health and Disease.A DNA methylation signature associated with the epigenetic repression of glycine N-methyltransferase in human hepatocellular carcinoma.How tissue damage MET metabolism: Regulation of the systemic damage response.Human hepatic gene expression signature of non-alcoholic fatty liver disease progression, a meta-analysis.Salvianolic acid B maintained stem cell pluripotency and increased proliferation rate by activating Jak2-Stat3 combined with EGFR-Erk1/2 pathways.Utilizing glycine N-methyltransferasegene knockout mice as a model for identification of missing proteins in hepatocellular carcinoma.Maternal Consumption of Low-Isoflavone Soy Protein Isolate Confers the Increased Predisposition to Alcoholic Liver Injury in Adult Rat Offspring.A large electronic-health-record-based genome-wide study of serum lipids.Glycine N-methyltransferase inhibits aristolochic acid nephropathy by increasing CYP3A44 and decreasing NQO1 expression in female mouse hepatocytes.AAV serotype 8-mediated liver specific GNMT expression delays progression of hepatocellular carcinoma and prevents carbon tetrachloride-induced liver damageMicroRNA-224 down-regulates Glycine N-methyltransferase gene expression in Hepatocellular Carcinoma
P2860
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P2860
Glycine N-methyltransferase-/- mice develop chronic hepatitis and glycogen storage disease in the liver
description
2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im November 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/11/01)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/11/01)
@nl
наукова стаття, опублікована в листопаді 2007
@uk
مقالة علمية (نشرت في نوفمبر 2007)
@ar
name
Glycine N-methyltransferase-/- ...... n storage disease in the liver
@ast
Glycine N-methyltransferase-/- ...... n storage disease in the liver
@en
Glycine N-methyltransferase-/- ...... n storage disease in the liver
@nl
type
label
Glycine N-methyltransferase-/- ...... n storage disease in the liver
@ast
Glycine N-methyltransferase-/- ...... n storage disease in the liver
@en
Glycine N-methyltransferase-/- ...... n storage disease in the liver
@nl
prefLabel
Glycine N-methyltransferase-/- ...... n storage disease in the liver
@ast
Glycine N-methyltransferase-/- ...... n storage disease in the liver
@en
Glycine N-methyltransferase-/- ...... n storage disease in the liver
@nl
P2093
P2860
P3181
P356
P1433
P1476
Glycine N-methyltransferase-/- ...... n storage disease in the liver
@en
P2093
Anna Fen-Yau Li
Shih-Ping Liu
Shiu-Feng Huang
Ting-Fen Tsai
Yann-Jang Chen
Yi-Ming Arthur Chen
Ying-Hue Lee
Ying-Shiuan Li
P2860
P304
P3181
P356
10.1002/HEP.21863
P407
P577
2007-11-01T00:00:00Z