Ablation of Cypher, a PDZ-LIM domain Z-line protein, causes a severe form of congenital myopathy
about
Insights into the molecular evolution of the PDZ/LIM family and identification of a novel conserved protein motifCalsarcin-3, a novel skeletal muscle-specific member of the calsarcin family, interacts with multiple Z-disc proteinsThe knockout of miR-143 and -145 alters smooth muscle cell maintenance and vascular homeostasis in mice: correlates with human diseaseTbx20 regulates a genetic program essential to adult mouse cardiomyocyte functionMuscle regeneration in dystrophin-deficient mdx mice studied by gene expression profilingUnderstanding cardiac sarcomere assembly with zebrafish geneticsLoss of the cytoskeletal protein Pdlim7 predisposes mice to heart defects and hemostatic dysfunctionAlp/Enigma family proteins cooperate in Z-disc formation and myofibril assemblyThe vertebrate muscle Z-disc: sarcomere anchor for structure and signallingZasp is required for the assembly of functional integrin adhesion sitesThe LIM domain: from the cytoskeleton to the nucleusFour and a half LIM protein 1 binds myosin-binding protein C and regulates myosin filament formation and sarcomere assemblyA class III PDZ binding motif in the myotilin and FATZ families binds enigma family proteins: a common link for Z-disc myopathiesMyofibrillar myopathiesAblation of the cardiac-specific gene leucine-rich repeat containing 10 (Lrrc10) results in dilated cardiomyopathyZasp52, a Core Z-disc Protein in Drosophila Indirect Flight Muscles, Interacts with α-Actinin via an Extended PDZ DomainTargeted ablation of PINCH1 and PINCH2 from murine myocardium results in dilated cardiomyopathy and early postnatal lethalityMyospryn is a direct transcriptional target for MEF2A that encodes a striated muscle, alpha-actinin-interacting, costamere-localized proteinAttenuation of cardiac remodeling after myocardial infarction by muscle LIM protein-calcineurin signaling at the sarcomeric Z-discTargeted Deletion of the Muscular Dystrophy Gene myotilin Does Not Perturb Muscle Structure or Function in MiceMononuclear muscle cells in Drosophila ovaries revealed by GFP protein trapsPdlim7 (LMP4) regulation of Tbx5 specifies zebrafish heart atrio-ventricular boundary and valve formationAnalysis of tarantula skeletal muscle protein sequences and identification of transcriptional isoformsCharacterization of the interaction between Actinin-Associated LIM Protein (ALP) and the rod domain of alpha-actinin.Z-disc-associated, alternatively spliced, PDZ motif-containing protein (ZASP) mutations in the actin-binding domain cause disruption of skeletal muscle actin filaments in myofibrillar myopathy.Splice variants of enigma homolog, differentially expressed during heart development, promote or prevent hypertrophy.ALP/Enigma PDZ-LIM domain proteins in the heart.Obscurin determines the architecture of the longitudinal sarcoplasmic reticulum.MLP (muscle LIM protein) as a stress sensor in the heart.ALP and MLP distribution during myofibrillogenesis in cultured cardiomyocytes.Deletion of Drosophila muscle LIM protein decreases flight muscle stiffness and power generation.A Cypher/ZASP mutation associated with dilated cardiomyopathy alters the binding affinity to protein kinase C.Loss of function of hNav1.5 by a ZASP1 mutation associated with intraventricular conduction disturbances in left ventricular noncompactionZasp regulates integrin activation.The ZASP-like motif in actinin-associated LIM protein is required for interaction with the alpha-actinin rod and for targeting to the muscle Z-line.Drosophila melanogaster muscle LIM protein and alpha-actinin function together to stabilize muscle cytoarchitecture: a potential role for Mlp84B in actin-crosslinking.Cypher/ZASP is a novel A-kinase anchoring protein.A mutation in the Z-line Cypher/ZASP protein is associated with arrhythmogenic right ventricular cardiomyopathy.Z-band alternatively spliced PDZ motif protein (ZASP) is the major O-linked β-N-acetylglucosamine-substituted protein in human heart myofibrilsActin-binding protein alpha-actinin-1 interacts with the metabotropic glutamate receptor type 5b and modulates the cell surface expression and function of the receptor.
P2860
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P2860
Ablation of Cypher, a PDZ-LIM domain Z-line protein, causes a severe form of congenital myopathy
description
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2001
@ast
im November 2001 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2001/11/12)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/11/12)
@nl
наукова стаття, опублікована в листопаді 2001
@uk
مقالة علمية (نشرت في 12-11-2001)
@ar
name
Ablation of Cypher, a PDZ-LIM ...... re form of congenital myopathy
@ast
Ablation of Cypher, a PDZ-LIM ...... re form of congenital myopathy
@en
Ablation of Cypher, a PDZ-LIM ...... re form of congenital myopathy
@nl
type
label
Ablation of Cypher, a PDZ-LIM ...... re form of congenital myopathy
@ast
Ablation of Cypher, a PDZ-LIM ...... re form of congenital myopathy
@en
Ablation of Cypher, a PDZ-LIM ...... re form of congenital myopathy
@nl
prefLabel
Ablation of Cypher, a PDZ-LIM ...... re form of congenital myopathy
@ast
Ablation of Cypher, a PDZ-LIM ...... re form of congenital myopathy
@en
Ablation of Cypher, a PDZ-LIM ...... re form of congenital myopathy
@nl
P2093
P2860
P3181
P356
P1476
Ablation of Cypher, a PDZ-LIM ...... re form of congenital myopathy
@en
P2093
Martone ME
Shelton GD
P2860
P304
P3181
P356
10.1083/JCB.200107092
P407
P577
2001-11-05T00:00:00Z