Mammary gland development requires syndecan-1 to create a beta-catenin/TCF-responsive mammary epithelial subpopulation
about
An expression signature of syndecan-1 (CD138), E-cadherin and c-met is associated with factors of angiogenesis and lymphangiogenesis in ductal breast carcinoma in situThe human D-glucuronyl C5-epimerase gene is transcriptionally activated through the beta-catenin-TCF4 pathwayInsights into the key roles of proteoglycans in breast cancer biology and translational medicineThe Wnt receptor, Lrp5, is expressed by mouse mammary stem cells and is required to maintain the basal lineageThe transforming activity of Wnt effectors correlates with their ability to induce the accumulation of mammary progenitor cellsWnt signaling induces differentiation of progenitor cells in organotypic keratinocyte culturesAssociation of loss of epithelial syndecan-1 with stage and local metastasis of colorectal adenocarcinomas: an immunohistochemical study of clinically annotated tumors.Wnt4 is not sufficient to induce lobuloalveolar mammary development.Loss of the heparan sulfate sulfotransferase, Ndst1, in mammary epithelial cells selectively blocks lobuloalveolar development in miceEither ZEB1 or ZEB2/SIP1 can play a central role in regulating the Epstein-Barr virus latent-lytic switch in a cell-type-specific manner.Key signaling nodes in mammary gland development and cancer: β-catenin.Effect of mutant β-catenin on liver growth homeostasis and hepatocarcinogenesis in transgenic miceStage-dependent regulation of mammary ductal branching by heparan sulfate and HGF-cMet signaling.Syndecan-1 (CD138) modulates triple-negative breast cancer stem cell properties via regulation of LRP-6 and IL-6-mediated STAT3 signaling.Wnt/beta-catenin signaling in oral tissue development and disease.Regulation of matrix biology by matrix metalloproteinases.Use of an in vivo animal model for assessing the role of integrin α(6)β(4) and syndecan-1 in early steps in papillomavirus infection.The origin of breast tumor heterogeneity.IGF1R inhibition in mammary epithelia promotes canonical Wnt signaling and Wnt1-driven tumorsBrain tumour stem cells: the undercurrents of human brain cancer and their relationship to neural stem cells.Syndecan-1 regulates alphavbeta3 and alphavbeta5 integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor.Prognostic significance of RSPO1, WNT1, P16, WT1, and SDC1 expressions in invasive ductal carcinoma of the breast.Cellular observations enabled by microculture: paracrine signaling and population demographicsSyndecans in cartilage breakdown and synovial inflammation.Wnt Signaling Cascades and the Roles of Syndecan Proteoglycans.Pubertal Mammary Gland Development: Elucidation of In Vivo Morphogenesis Using Murine Models.Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1.HS3ST2 modulates breast cancer cell invasiveness via MAP kinase- and Tcf4 (Tcf7l2)-dependent regulation of protease and cadherin expression.Links between transforming growth factor-beta and canonical Wnt signaling yield new insights into breast cancer susceptibility, suppression and tumor heterogeneity.Dually modified transmembrane proteoglycans in development and disease.Juvenile syndecan-1 null mice are protected from carcinogen-induced tumor development.
P2860
Q21195234-F3A58065-838F-4083-9E2A-C41D479AD41CQ24300738-90F76A97-21CB-4B6F-8FF4-AC4D8C880238Q28085548-BF2FDB1D-3DDA-45B0-A6AD-251E2B7EE871Q28505604-E40490AE-1A8C-4092-A182-C9A97606689CQ33199519-E1127851-CB1E-42C4-BFC2-43B4804290F7Q33274270-C4870E2E-B7D2-4CA5-9418-3B68D2469926Q33347864-1DB39B45-A1EF-415F-A157-89519D6D8376Q33514113-1B6CFC72-6CD1-4D3A-8C0F-25B4AA16829AQ33587338-09601C9F-F7FE-4E13-AB62-D4C043D44AD1Q33877497-9554F99E-5A8C-43F2-9E64-0D3480EA4AFFQ34613461-F0A4A440-32EC-4324-B2FE-14F5B64A94B3Q34978658-D5B269E4-524A-4571-A5F8-71AB7C29A8EFQ35056355-54423FD9-8804-42F1-BD52-AC9F68C1197BQ35083176-5A89B26F-7527-4645-8EAF-CA25BBF10780Q35119945-6B429EAD-ED5F-4F54-93F8-FF23DDE593B1Q35885655-ED08160F-95FB-40A6-8A83-A07ACB947460Q36303591-0811DE2E-B7F3-4B65-9DA7-2E2EA09C1F2EQ36525461-7228C48A-D732-4146-BC5F-DBCB179D88D8Q36664343-383318AA-55F4-4EBF-89F8-7A7D4A3EE114Q36740051-10A2A81C-EBBB-46D1-AB55-9FED9D60062AQ37234281-48CE84EB-A6BD-49D1-8A11-AE71B9810C8DQ37428209-7E6252FC-315D-4A21-A87E-8C1F9D6A61AFQ37469001-453E2DC6-DAEF-4FC6-8E3C-4437916A50B0Q38054541-9A2EB9AB-4F71-4570-B576-EC39AFB64E5EQ38441061-205D2C41-49E0-4982-B3C8-FCE83914E240Q38802182-41AAF864-E13B-4AAC-9B8F-9B14E1FA60D3Q42280649-A0BA23A6-27BB-4E5D-854A-D0DAE118E03CQ42457789-AC2634E2-21A6-4C53-893A-4F465B603BF8Q42586464-C3FE031D-FDF0-4A5D-90A1-208B535A5253Q47240245-A4BCB030-51A1-48F1-908C-581AC8E083C9Q52007642-42697F3F-9A8F-40A7-8954-73D5912D6180
P2860
Mammary gland development requires syndecan-1 to create a beta-catenin/TCF-responsive mammary epithelial subpopulation
description
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im Dezember 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/12/18)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/12/18)
@nl
наукова стаття, опублікована в грудні 2003
@uk
مقالة علمية (نشرت في 18-12-2003)
@ar
name
Mammary gland development requ ...... mmary epithelial subpopulation
@ast
Mammary gland development requ ...... mmary epithelial subpopulation
@en
Mammary gland development requ ...... mmary epithelial subpopulation
@nl
type
label
Mammary gland development requ ...... mmary epithelial subpopulation
@ast
Mammary gland development requ ...... mmary epithelial subpopulation
@en
Mammary gland development requ ...... mmary epithelial subpopulation
@nl
prefLabel
Mammary gland development requ ...... mmary epithelial subpopulation
@ast
Mammary gland development requ ...... mmary epithelial subpopulation
@en
Mammary gland development requ ...... mmary epithelial subpopulation
@nl
P2093
P2860
P356
P1433
P1476
Mammary gland development requ ...... mmary epithelial subpopulation
@en
P2093
Bob Y. Liu
Caroline M. Alexander
Vicki Leatherberry
Young Chul Kim
P2860
P2888
P304
P356
10.1038/SJ.ONC.1207217
P407
P577
2003-12-18T00:00:00Z
P5875
P6179
1004757041