Otogelin: a glycoprotein specific to the acellular membranes of the inner ear
about
A pH-regulated dimeric bouquet in the structure of von Willebrand factorOTOF encodes multiple long and short isoforms: genetic evidence that the long ones underlie recessive deafness DFNB9.Mutations in PTPRQ are a cause of autosomal-recessive nonsyndromic hearing impairment DFNB84 and associated with vestibular dysfunctionIsolation from cochlea of a novel human intronless gene with predominant fetal expressionVestibular defects in head-tilt mice result from mutations in Nox3, encoding an NADPH oxidaseMammalian Otolin: a multimeric glycoprotein specific to the inner ear that interacts with otoconial matrix protein Otoconin-90 and Cerebellin-1Characterization of otoconin-95, the major protein of murine otoconia, provides insights into the formation of these inner ear biomineralsOtoancorin, an inner ear protein restricted to the interface between the apical surface of sensory epithelia and their overlying acellular gels, is defective in autosomal recessive deafness DFNB22.A mouse model for human deafness DFNB22 reveals that hearing impairment is due to a loss of inner hair cell stimulation.Fdp, a new fibrocyte-derived protein related to MIA/CD-RAP, has an in vitro effect on the early differentiation of the inner ear mesenchymeTargeted disruption of otog results in deafness and severe imbalanceMutations in the gene encoding pejvakin, a newly identified protein of the afferent auditory pathway, cause DFNB59 auditory neuropathyOtolith tethering in the zebrafish otic vesicle requires Otogelin and α-TectorinA secretory cell type develops alongside multiciliated cells, ionocytes and goblet cells, and provides a protective, anti-infective function in the frog embryonic mucociliary epidermisExtracellular matrices associated with the apical surfaces of sensory epithelia in the inner ear: Molecular and structural diversitySimilar phenotypes caused by mutations in OTOG and OTOGL.Loss of the tectorial membrane protein CEACAM16 enhances spontaneous, stimulus-frequency, and transiently evoked otoacoustic emissions.Genetics of auditory mechano-electrical transduction.Three deaf mice: mouse models for TECTA-based human hereditary deafness reveal domain-specific structural phenotypes in the tectorial membraneMolecular biology of hearing.Deficient forward transduction and enhanced reverse transduction in the alpha tectorin C1509G human hearing loss mutation.The tectorial membrane: one slice of a complex cochlear sandwichTargeted ablation of connexin26 in the inner ear epithelial gap junction network causes hearing impairment and cell deathA subtracted cDNA library from the zebrafish (Danio rerio) embryonic inner ear.Molecular screens for inner ear genes.Molecular markers for cell types of the inner ear and candidate genes for hearing disordersLaser-induced collagen remodeling and deposition within the basilar membrane of the mouse cochlea.Mesothelin, Stereocilin, and Otoancorin are predicted to have superhelical structures with ARM-type repeats.Source and role of endolymph macromolecules.The structure and assembly of secreted mucins.Chromatin immunoselection defines a TAL-1 target geneCalcium oxalate stone formation in the inner ear as a result of an Slc26a4 mutation.Cell type-specific transcriptome analysis reveals a major role for Zeb1 and miR-200b in mouse inner ear morphogenesis.A deafness mutation isolates a second role for the tectorial membrane in hearing.Expression, functional, and structural analysis of proteins critical for otoconia developmentApplications of genomics in the inner ear.Mechanisms of otoconia and otolith developmentTargeted discovery of novel human exons by comparative genomics.Mixing model systems: using zebrafish and mouse inner ear mutants and other organ systems to unravel the mystery of otoconial developmentA new Otogelin ENU mouse model for autosomal-recessive nonsyndromic moderate hearing impairment
P2860
Q24324184-B8E55D5D-37E8-40D9-8D30-DFFC60B4C269Q24538784-3EF88441-DC66-4749-AEEC-496B6E954C77Q24602944-F1E9B5C2-F256-4EFB-822B-BABAE36BFE53Q24650440-5366B77B-E4B0-47A3-A0A2-F2738F252B99Q28249779-FD40827F-B06F-49DD-B04D-AEB12885E981Q28475514-B1995590-0268-484E-9FDB-750DB3548143Q28511776-084EA4FA-E7FE-4DC1-8D7F-F4319D7EF577Q28512415-C8DDE97A-2DC7-4E8E-B206-0931DDFFABEBQ28590148-0C362120-52D1-486E-9AF8-D65E5E4EB714Q28591745-24B75701-311B-48CB-A6A9-821FDADCDD5FQ28592378-F9A9A081-F184-4414-8703-1C00FA0AE57CQ28594398-25108A93-2093-49EA-9B4F-6DE25065F1DAQ28652359-A44BFE06-1B7C-4A37-A3B0-C96A39644894Q28657650-60639591-0DF8-4B3D-8085-94C6E452C8BCQ29039160-48B6F46E-857E-41DE-AC12-FF9E1766D75AQ30412991-D9BC36C8-CD9F-4E6F-9AA7-65E81CDF94A8Q30420092-FEF9EF85-BDD3-43C1-9759-B34E6A0EA2E9Q30421422-611D7E27-EC02-444C-8175-1B5795D7F623Q30439995-4EF9C2F0-03E5-40AB-89D8-92C03952BB61Q30467847-10B4CBBB-8B44-4AFE-9657-97C3D45DD39CQ30476618-73E19D42-A279-4C78-A426-2BC7BD611C89Q30481427-672B15AE-E0AD-4E5A-BAEE-6F564CB27473Q30578611-00CC161F-DFCE-4C40-B686-F162FD62776BQ31066454-F70BC07F-1DA2-4603-BE32-B4F7F25A75BEQ31114341-959FA67F-52E7-45D0-8F5F-460BDF779806Q32021952-DAC0F363-77EC-4BB5-8906-18A3E88EB800Q33283605-05AE5480-C8B9-4865-A5A4-1744A5F79320Q33398152-F87519D4-4456-45DA-98D0-9FA2032FF29EQ33669193-8159F27A-F5A4-4C0A-A5B2-A05DE6DBE52BQ33763293-65A2EC50-63B2-4215-B428-414489B428B0Q33889431-C92755EA-CD3C-482C-856C-56DE24D9FDA8Q33967195-F7DAE3D3-B4CD-4EF5-B64D-B9AE4A36054CQ34042739-1C77E8EB-2607-4B42-B4AF-ABAAF63B9373Q34431118-6B9DE117-7EB5-47A3-AD71-B20AA591BC2CQ34724531-F84E5A86-1445-48B9-A062-EB0F3F43EADEQ35574942-592ECC09-3108-4987-84C0-F821A17A3EA7Q35788255-CCE2A70F-4912-413E-9078-CE493B17A15CQ36177393-B6BB8065-4BBB-44BE-8985-B74CACB91EEFQ36178660-C11A7C49-C305-4E46-B2F4-427C3CEB838DQ36319732-469893CC-5D10-4E2D-AB83-C1A2D54430A7
P2860
Otogelin: a glycoprotein specific to the acellular membranes of the inner ear
description
1997 nî lūn-bûn
@nan
1997 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
name
Otogelin: a glycoprotein specific to the acellular membranes of the inner ear
@ast
Otogelin: a glycoprotein specific to the acellular membranes of the inner ear
@en
Otogelin: a glycoprotein specific to the acellular membranes of the inner ear
@nl
type
label
Otogelin: a glycoprotein specific to the acellular membranes of the inner ear
@ast
Otogelin: a glycoprotein specific to the acellular membranes of the inner ear
@en
Otogelin: a glycoprotein specific to the acellular membranes of the inner ear
@nl
prefLabel
Otogelin: a glycoprotein specific to the acellular membranes of the inner ear
@ast
Otogelin: a glycoprotein specific to the acellular membranes of the inner ear
@en
Otogelin: a glycoprotein specific to the acellular membranes of the inner ear
@nl
P2860
P50
P356
P1476
Otogelin: a glycoprotein specific to the acellular membranes of the inner ear
@en
P2093
M Leibovici
P2860
P304
14450-14455
P356
10.1073/PNAS.94.26.14450
P407
P577
1997-12-01T00:00:00Z