Deficiency in ubiquitin ligase TRIM2 causes accumulation of neurofilament light chain and neurodegeneration
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Identification of a novel Bcl-2-interacting mediator of cell death (Bim) E3 ligase, tripartite motif-containing protein 2 (TRIM2), and its role in rapid ischemic tolerance-induced neuroprotectionDeficiency of the E3 ubiquitin ligase TRIM32 in mice leads to a myopathy with a neurogenic componentUbiquitin ligase TRIM3 controls hippocampal plasticity and learning by regulating synaptic γ-actin levelsThe let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2Genome-wide association study of severity in multiple sclerosis.Origin and diversification of TRIM ubiquitin ligases.Proteome of acidic phospholipid-binding proteins: spatial and temporal regulation of Coronin 1A by phosphoinositidesA novel Netrin-1-sensitive mechanism promotes local SNARE-mediated exocytosis during axon branching.Intermediate filament aggregates cause mitochondrial dysmotility and increase energy demands in giant axonal neuropathy.Expression, purification, crystallization and preliminary X-ray diffraction analysis of the C-terminal NHL domain of human TRIM2Methylation of CpG sites in RNF180 DNA promoter prediction poor survival of gastric cancer.TRIM32 protein sensitizes cells to tumor necrosis factor (TNFα)-induced apoptosis via its RING domain-dependent E3 ligase activity against X-linked inhibitor of apoptosis (XIAP).Brat promotes stem cell differentiation via control of a bistable switch that restricts BMP signaling.Neurofilament Phosphorylation during Development and Disease: Which Came First, the Phosphorylation or the Accumulation?Trim69 regulates zebrafish brain development by ap-1 pathway.Interrogation of brain miRNA and mRNA expression profiles reveals a molecular regulatory network that is perturbed by mutant huntingtin.TRIM59, a novel multiple cancer biomarker for immunohistochemical detection of tumorigenesis.Neurofilaments at a glance.Global analysis of the haematopoietic and endothelial transcriptome during zebrafish developmentPromoter methylation of RNF180 is associated with H.pylori infection and serves as a marker for gastric cancer and atrophic gastritisDNA-binding specificity and in vivo targets of Caenorhabditis elegans nuclear factor I.Mediation of the malignant biological characteristics of gastric cancer cells by the methylated CpG islands in RNF180 DNA promoter.S-nitrosation and ubiquitin-proteasome system interplay in neuromuscular disorders.TRIM family: Pleiotropy and diversification through homomultimer and heteromultimer formation.The ubiquitin-proteasome system in retinal health and disease.Neurofilament dynamics and involvement in neurological disorders.Polyubiquitin chain-dependent protein degradation in TRIM30 cytoplasmic bodies.Common genetic variants in NEFL influence gene expression and neuroblastoma risk.Expression Profiling of Clinical Specimens Supports the Existence of Neural Progenitor-Like Stem Cells in Basal Breast Cancers.siRNA screen for genes that affect Junín virus entry uncovers voltage-gated calcium channels as a therapeutic target.Neurofilaments and Neurofilament Proteins in Health and Disease.Characterization of the gene structure, functional significance, and clinical application of RNF180, a novel gene in gastric cancer.Identification of residues within the L2 region of rhesus TRIM5alpha that are required for retroviral restriction and cytoplasmic body localization.Bioinformatics analysis of potential essential genes that response to the high intraocular pressure on astrocyte due to glaucoma.MicroRNA-181c Ameliorates Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion in Rats.Cerebral Small Vessel Disease Is Associated with Dysregulation in the Ubiquitin Proteasome System and Other Major Cellular Pathways in Specific Brain Regions.QuaDMutEx: quadratic driver mutation explorerRegulation of neuronal survival and morphology by the E3 ubiquitin ligase RNF157.Whole-exome sequencing implicates UBE3D in age-related macular degeneration in East Asian populations.Diagnostic and Prognostic Biomarkers in Amyotrophic Lateral Sclerosis: Neurofilament Light Chain Levels in Definite Subtypes of Disease.
P2860
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P248
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P2860
Deficiency in ubiquitin ligase TRIM2 causes accumulation of neurofilament light chain and neurodegeneration
description
2008 nî lūn-bûn
@nan
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Deficiency in ubiquitin ligase ...... ht chain and neurodegeneration
@ast
Deficiency in ubiquitin ligase ...... ht chain and neurodegeneration
@en
Deficiency in ubiquitin ligase ...... ht chain and neurodegeneration
@nl
type
label
Deficiency in ubiquitin ligase ...... ht chain and neurodegeneration
@ast
Deficiency in ubiquitin ligase ...... ht chain and neurodegeneration
@en
Deficiency in ubiquitin ligase ...... ht chain and neurodegeneration
@nl
prefLabel
Deficiency in ubiquitin ligase ...... ht chain and neurodegeneration
@ast
Deficiency in ubiquitin ligase ...... ht chain and neurodegeneration
@en
Deficiency in ubiquitin ligase ...... ht chain and neurodegeneration
@nl
P2093
P2860
P3181
P356
P1476
Deficiency in ubiquitin ligase ...... ht chain and neurodegeneration
@en
P2093
André Pires-da Silva
Francesco Ferraguti
Gonzalo Alvarez-Bolado
Kun Ping Lu
Martin Balastik
Peter Gruss
Tae Ho Lee
P2860
P304
12016-12021
P3181
P356
10.1073/PNAS.0802261105
P407
P577
2008-08-07T00:00:00Z