Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways
about
DYRK1A autophosphorylation on serine residue 520 modulates its kinase activity via 14-3-3 bindingPromotion of importin alpha-mediated nuclear import by the phosphorylation-dependent binding of cargo protein to 14-3-3Identification of a proline-rich Akt substrate as a 14-3-3 binding partnerAging as an event of proteostasis collapseThe forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expressionExpression of Drosophila FOXO regulates growth and can phenocopy starvation14-3-3ε Is required for germ cell migration in DrosophilaCrystal structure of the human FOXO3a-DBD/DNA complex suggests the effects of post-translational modificationThe role of insulin/IGF-1 signaling in the longevity of model invertebrates, C. elegans and D. melanogasterRegulation of molecular chaperone gene transcription involves the serine phosphorylation, 14-3-3 epsilon binding, and cytoplasmic sequestration of heat shock factor 1FoxO6 transcriptional activity is regulated by Thr26 and Ser184, independent of nucleo-cytoplasmic shuttlingBoth the N-terminal loop and wing W2 of the forkhead domain of transcription factor Foxo4 are important for DNA bindingPTEN negatively regulates MAPK signaling during Caenorhabditis elegans vulval developmentMolecular dynamics and in vitro analysis of Connexin43: A new 14-3-3 mode-1 interacting proteinModulation of p53 degradation via MDM2-mediated ubiquitylation and the ubiquitin-proteasome system during reperfusion after stroke: role of oxidative stressThe evolution of Fox genes and their role in development and diseaseDirect inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegansFOXO transcription factors at the interface between longevity and tumor suppressionBimodal regulation of FoxO3 by AKT and 14-3-314-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transportOver-expression of 14-3-3zeta is an early event in oral cancer.14-3-3 protein masks the DNA binding interface of forkhead transcription factor FOXO4.Identification of a suppressive mechanism for Hedgehog signaling through a novel interaction of Gli with 14-3-3.14-3-3zeta escorts CCTalpha for calcium-activated nuclear import in lung epithelia.Insulin/IGF-1 and ROS signaling pathway cross-talk in aging and longevity determinationMicroarray-based analysis of differential gene expression between infective and noninfective larvae of Strongyloides stercoralis.Transgenic C. elegans dauer larvae expressing hookworm phospho null DAF-16/FoxO exit dauerHow do 14-3-3 proteins work?-- Gatekeeper phosphorylation and the molecular anvil hypothesis.Strongyloides stercoralis age-1: a potential regulator of infective larval development in a parasitic nematode.RNAseq analysis of the parasitic nematode Strongyloides stercoralis reveals divergent regulation of canonical dauer pathways.Dynamic multiprotein assemblies shape the spatial structure of cell signalingA model of acquired autoresistance to a potent ErbB2 tyrosine kinase inhibitor and a therapeutic strategy to prevent its onset in breast cancerDifferential roles of ATM- and Chk2-mediated phosphorylations of Hdmx in response to DNA damage.Microphthalmia-associated transcription factor interactions with 14-3-3 modulate differentiation of committed myeloid precursorsThe many forks in FOXO's road.14-3-3 proteins in apoptosis.The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation.Dynamic interactions between 14-3-3 proteins and phosphoproteins regulate diverse cellular processes.14-3-3 proteins: a number of functions for a numbered protein.The role of phosphoinositide 3-kinase signaling in intestinal inflammation
P2860
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P2860
Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways
description
2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2001
@ast
im April 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/04/20)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/04/20)
@nl
наукова стаття, опублікована у квітні 2001
@uk
name
Phosphatidylinositol 3-kinase ...... nd 14-3-3-independent pathways
@ast
Phosphatidylinositol 3-kinase ...... nd 14-3-3-independent pathways
@en
Phosphatidylinositol 3-kinase ...... nd 14-3-3-independent pathways
@nl
type
label
Phosphatidylinositol 3-kinase ...... nd 14-3-3-independent pathways
@ast
Phosphatidylinositol 3-kinase ...... nd 14-3-3-independent pathways
@en
Phosphatidylinositol 3-kinase ...... nd 14-3-3-independent pathways
@nl
prefLabel
Phosphatidylinositol 3-kinase ...... nd 14-3-3-independent pathways
@ast
Phosphatidylinositol 3-kinase ...... nd 14-3-3-independent pathways
@en
Phosphatidylinositol 3-kinase ...... nd 14-3-3-independent pathways
@nl
P2093
P3181
P356
P1476
Phosphatidylinositol 3-kinase ...... nd 14-3-3-independent pathways
@en
P2093
C. M. Cahill
G. Tzivion
M. Alexander-Bridges
P304
13402–13410
P3181
P356
10.1074/JBC.M010042200
P407
P577
2001-04-20T00:00:00Z