SOCS1 deficiency results in accelerated mammary gland development and rescues lactation in prolactin receptor-deficient mice
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Threonine 391 phosphorylation of the human prolactin receptor mediates a novel interaction with 14-3-3 proteinsCaveolin-1-deficient mice show accelerated mammary gland development during pregnancy, premature lactation, and hyperactivation of the Jak-2/STAT5a signaling cascade.Nuclear Jak2 and transcription factor NF1-C2: a novel mechanism of prolactin signaling in mammary epithelial cellsSOCS2 negatively regulates growth hormone action in vitro and in vivoThe role of prolactin in mammary carcinoma.Roles and regulation of stat family transcription factors in human breast cancer.c-myc as a mediator of accelerated apoptosis and involution in mammary glands lacking Socs3.Ovarian insufficiency and early pregnancy loss induced by activation of the innate immune systemA future for transgenic livestock.Conditional deletion of Shp2 in the mammary gland leads to impaired lobulo-alveolar outgrowth and attenuated Stat5 activationJAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis.Prolactin and the prolactin receptor: new targets of an old hormone.Angiotensin II accelerates mammary gland development independently of high blood pressure in pregnancy-associated hypertensive mice.Information networks in the mammary gland.SOCS1: a potent and multifaceted regulator of cytokines and cell-mediated inflammation.Interpretation of cytokine signaling through the transcription factors STAT5A and STAT5BSTAT signaling in mammary gland differentiation, cell survival and tumorigenesisContributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia.Dysregulated STAT1-SOCS1 control of JAK2 promotes mammary luminal progenitor cell survival and drives ERα(+) tumorigenesis.Cytokine networks that mediate epithelial cell-macrophage crosstalk in the mammary gland: implications for development and cancer.SHP-2 regulates SOCS-1-mediated Janus kinase-2 ubiquitination/degradation downstream of the prolactin receptor.Potential roles of suppressor of cytokine signaling in wound healing.Breast cancer: the menacing face of Janus kinase.Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling.A mutation in the viral sensor 2'-5'-oligoadenylate synthetase 2 causes failure of lactation.Suppressor of cytokine signaling 1 is required for the differentiation of CD4+ T cells.
P2860
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P2860
SOCS1 deficiency results in accelerated mammary gland development and rescues lactation in prolactin receptor-deficient mice
description
2001 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2001
@ast
im Juli 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/07/01)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/07/01)
@nl
наукова стаття, опублікована в липні 2001
@uk
مقالة علمية (نشرت في يوليو 2001)
@ar
name
SOCS1 deficiency results in ac ...... lactin receptor-deficient mice
@ast
SOCS1 deficiency results in ac ...... lactin receptor-deficient mice
@en
SOCS1 deficiency results in ac ...... lactin receptor-deficient mice
@nl
type
label
SOCS1 deficiency results in ac ...... lactin receptor-deficient mice
@ast
SOCS1 deficiency results in ac ...... lactin receptor-deficient mice
@en
SOCS1 deficiency results in ac ...... lactin receptor-deficient mice
@nl
prefLabel
SOCS1 deficiency results in ac ...... lactin receptor-deficient mice
@ast
SOCS1 deficiency results in ac ...... lactin receptor-deficient mice
@en
SOCS1 deficiency results in ac ...... lactin receptor-deficient mice
@nl
P2093
P2860
P921
P356
P1433
P1476
SOCS1 deficiency results in ac ...... lactin receptor-deficient mice
@en
P2093
C. J. Ormandy
D. J. Hilton
G. J. Lindeman
J. G. Zhang
J. Visvader
M. J. Naylor
M. Santamaria
S. Wittlin
P2860
P304
P356
10.1101/GAD.880801
P577
2001-07-01T00:00:00Z