Tissue-specific requirements of beta-catenin in external genitalia development
about
Genetic interactions of the androgen and Wnt/beta-catenin pathways for the masculinization of external genitaliaDelineating a conserved genetic cassette promoting outgrowth of body appendagesClarification of mammalian cloacal morphogenesis using high-resolution episcopic microscopyDysregulation of Wnt inhibitory factor 1 (Wif1) expression resulted in aberrant Wnt-β-catenin signaling and cell death of the cloaca endoderm, and anorectal malformations.Disruption of the temporally regulated cloaca endodermal β-catenin signaling causes anorectal malformations.Embryonic origin and remodeling of the urinary and digestive outlets.Sexually dimorphic expression of Mafb regulates masculinization of the embryonic urethral formation.LEF1 identifies androgen-independent epithelium in the developing prostate.Msx2 and Foxn1 regulate nail homeostasis.The inductive role of Wnt-β-Catenin signaling in the formation of oral apparatus.Constitutive activation of ectodermal β-catenin induces ectopic outgrowths at various positions in mouse embryo and affects abdominal ventral body wall closure.Comparative gene expression analysis of genital tubercle development reveals a putative appendicular Wnt7 network for the epidermal differentiationSix1 and Eya1 are critical regulators of peri-cloacal mesenchymal progenitors during genitourinary tract development.Tissue-specific roles of Fgfr2 in development of the external genitalia.Molecular mechanisms of external genitalia developmentTiming of androgen receptor disruption and estrogen exposure underlies a spectrum of congenital penile anomalies.Development of the external genitalia: conserved and divergent mechanisms of appendage patterning.Disruption of Wnt/β-catenin signaling in odontoblasts and cementoblasts arrests tooth root development in postnatal mouse teeth.The Genetic and Environmental Factors Underlying Hypospadias.Functional and phylogenetic analysis shows that Fgf8 is a marker of genital induction in mammals but is not required for external genital developmentConstruction and characterization of a doxycycline-inducible transgenic system in Msx2 expressing cellsTemporal and spatial dissection of Shh signaling in genital tubercle development.Dosage-dependent hedgehog signals integrated with Wnt/beta-catenin signaling regulate external genitalia formation as an appendicular program.New horizons at the caudal embryos: coordinated urogenital/reproductive organ formation by growth factor signaling.Dkk1 in the peri-cloaca mesenchyme regulates formation of anorectal and genitourinary tracts.Epispadias and the associated embryopathies: genetic and developmental basis.Requirement for basement membrane laminin α5 during urethral and external genital development.Functional analysis of ectodermal β-catenin during external genitalia formation.Induction of Wnt5a-expressing mesenchymal cells adjacent to the cloacal plate is an essential process for its proximodistal elongation and subsequent anorectal development.Isl1 mediates mesenchymal expansion in the developing external genitalia via regulation of Bmp4, Fgf10, and Wnt5a.Male germline recombination of a conditional allele by the widely used Dermo1-cre (Twist2-cre) transgene.16p11.2 transcription factor MAZ is a dosage-sensitive regulator of genitourinary development.Tissue-specific roles of FGF signaling in external genitalia development.Microcephaly, dysmorphic features, corneal dystrophy, hairy nipples, underdeveloped labioscrotal folds, and small cerebellum in four patients.
P2860
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P2860
Tissue-specific requirements of beta-catenin in external genitalia development
description
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im August 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/08/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/08/01)
@nl
наукова стаття, опублікована в серпні 2008
@uk
مقالة علمية (نشرت في أغسطس 2008)
@ar
name
Tissue-specific requirements of beta-catenin in external genitalia development
@ast
Tissue-specific requirements of beta-catenin in external genitalia development
@en
Tissue-specific requirements of beta-catenin in external genitalia development
@nl
type
label
Tissue-specific requirements of beta-catenin in external genitalia development
@ast
Tissue-specific requirements of beta-catenin in external genitalia development
@en
Tissue-specific requirements of beta-catenin in external genitalia development
@nl
prefLabel
Tissue-specific requirements of beta-catenin in external genitalia development
@ast
Tissue-specific requirements of beta-catenin in external genitalia development
@en
Tissue-specific requirements of beta-catenin in external genitalia development
@nl
P2093
P2860
P356
P1433
P1476
Tissue-specific requirements of beta-catenin in external genitalia development
@en
P2093
P2860
P304
P356
10.1242/DEV.020586
P407
P577
2008-08-01T00:00:00Z