Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity
about
Exome sequencing identifies INPPL1 mutations as a cause of opsismodysplasiaIncreased insulin action in SKIP heterozygous knockout miceMicroRNA-184 antagonizes microRNA-205 to maintain SHIP2 levels in epitheliaInsulin signalling and glucose transport in the ovary and ovarian function during the ovarian cycleInsulin receptor signaling in normal and insulin-resistant statesInositol polyphosphate 5-phosphatases; new players in the regulation of cilia and ciliopathiesPhosphoinositides: tiny lipids with giant impact on cell regulationPhosphoinositides: Key modulators of energy metabolismEvidence for SH2 domain-containing 5'-inositol phosphatase-2 (SHIP2) contributing to a lymphatic dysfunctionNMR Studies of a Heterotypic Sam−Sam Domain Association: The Interaction between the Lipid Phosphatase Ship2 and the EphA2 Receptor † , ‡Rapid signaling at the plasma membrane by a nuclear receptor for thyroid hormoneThe inositol Inpp5k 5-phosphatase affects osmoregulation through the vasopressin-aquaporin 2 pathway in the collecting systemThe inositol polyphosphate 5-phosphatase, PIPP, Is a novel regulator of phosphoinositide 3-kinase-dependent neurite elongation.Inpp5f is a polyphosphoinositide phosphatase that regulates cardiac hypertrophic responsivenessSHIP2 multiple functions: a balance between a negative control of PtdIns(3,4,5)P₃ level, a positive control of PtdIns(3,4)P₂ production, and intrinsic docking properties.Whole-genome analysis reveals that mutations in inositol polyphosphate phosphatase-like 1 cause opsismodysplasia.A mutation in synaptojanin 2 causes progressive hearing loss in the ENU-mutagenised mouse strain Mozart.Regulation of insulin signaling by the phosphatidylinositol 3,4,5-triphosphate phosphatase SKIP through the scaffolding function of Pak1Regulation of insulin signaling and glucose transporter 4 (GLUT4) exocytosis by phosphatidylinositol 3,4,5-trisphosphate (PIP3) phosphatase, skeletal muscle, and kidney enriched inositol polyphosphate phosphatase (SKIP).Identification of genes that regulate multiple cellular processes/responses in the context of lipotoxicity to hepatoma cells.Molecular determinants of Grb14-mediated inhibition of insulin signaling.Dynamics of mRNA and polysomal abundance in early 3T3-L1 adipogenesis.Biofluid lipidome: a source for potential diagnostic biomarkers.LyGDI, a novel SHIP-interacting protein, is a negative regulator of FcγR-mediated phagocytosis.The role of oxidative stress in the pathogenesis of type 2 diabetes: from molecular mechanism to clinical implication.The roles of ATF3, an adaptive-response gene, in high-fat-diet-induced diabetes and pancreatic beta-cell dysfunction.Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signalingSHIP2, a factor associated with diet-induced obesity and insulin sensitivity, attenuates FGF signaling in vivo.Genome-wide DNA Methylation Profiles of Small Intestine and Liver in Fast-growing and Slow-growing Weaning Piglets.A screen for novel phosphoinositide 3-kinase effector proteins.Frontier of epilepsy research - mTOR signaling pathway.Discovery and development of small molecule SHIP phosphatase modulators.The host phosphoinositide 5-phosphatase SHIP2 regulates dissemination of vaccinia virusRole of TAPP1 and TAPP2 adaptor binding to PtdIns(3,4)P2 in regulating insulin sensitivity defined by knock-in analysis.Mice with a disruption of the imprinted Grb10 gene exhibit altered body composition, glucose homeostasis, and insulin signaling during postnatal life.Nanoscale Landscape of Phosphoinositides Revealed by Specific Pleckstrin Homology (PH) Domains Using Single-molecule Superresolution Imaging in the Plasma Membrane.Insulin signaling pathways and cardiac growth.Variants of insulin-signaling inhibitor genes in type 2 diabetes and related metabolic abnormalities.Survival of monocytes and macrophages and their role in health and disease.SHIP2 regulates epithelial cell polarity through its lipid product, which binds to Dlg1, a pathway subverted by hepatitis C virus core protein
P2860
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P2860
Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity
description
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im Februar 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/02/01)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/02/01)
@nl
наукова стаття, опублікована в лютому 2005
@uk
مقالة علمية (نشرت في فبراير 2005)
@ar
name
Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity
@ast
Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity
@en
Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity
@nl
type
label
Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity
@ast
Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity
@en
Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity
@nl
prefLabel
Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity
@ast
Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity
@en
Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity
@nl
P2093
P2860
P3181
P356
P1433
P1476
Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity
@en
P2093
David J. Glass
George D. Yancopoulos
Jennifer Kintner
Ka-Man V. Lai
Karen Garcia
Katherine E. Wortley
Lori C. Gowen
Mark W. Sleeman
Stanley J. Wiegand
Trevor N. Stitt
P2860
P2888
P304
P3181
P356
10.1038/NM1178
P407
P577
2005-02-01T00:00:00Z