The cytoplasmic domain of neuropilin 1 is dispensable for angiogenesis, but promotes the spatial separation of retinal arteries and veins
about
Neuropilin 1 (NRP1) hypomorphism combined with defective VEGF-A binding reveals novel roles for NRP1 in developmental and pathological angiogenesisThe cytoplasmic domain of neuropilin-1 regulates focal adhesion turnoverThe neuropilin 1 cytoplasmic domain is required for VEGF-A-dependent arteriogenesisNRP1 function and targeting in neurovascular development and eye diseaseLymphangiogenesis and metastasis--a closer look at the neuropilin/semaphorin3 axisControl of cellular motility by neuropilin-mediated physical interactionsGenome-wide association study identifies loci on 12q24 and 13q32 associated with tetralogy of FallotNeuropilin-1 stimulates tumor growth by increasing fibronectin fibril assembly in the tumor microenvironmentImatinib inhibits VEGF-independent angiogenesis by targeting neuropilin 1-dependent ABL1 activation in endothelial cellsAn inside view: VEGF receptor trafficking and signalingNeuropilin-1 functions as a VEGFR2 co-receptor to guide developmental angiogenesis independent of ligand bindingAlk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch.Neural crest-derived SEMA3C activates endothelial NRP1 for cardiac outflow tract septation.Suppression of β3-integrin in mice triggers a neuropilin-1-dependent change in focal adhesion remodelling that can be targeted to block pathological angiogenesisVEGF-A/NRP1 stimulates GIPC1 and Syx complex formation to promote RhoA activation and proliferation in skin cancer cells.Neuropilin Functions as an Essential Cell Surface Receptor.Norrin/Frizzled4 signaling in retinal vascular development and blood brain barrier plasticity.Post-endocytic sorting of Plexin-D1 controls signal transduction and development of axonal and vascular circuits.How neuropilin-1 regulates receptor tyrosine kinase signalling: the knowns and known unknowns.Regulation of VEGF signaling by membrane traffic.Plexin structures are coming: opportunities for multilevel investigations of semaphorin guidance receptors, their cell signaling mechanisms, and functions.Function of members of the neuropilin family as essential pleiotropic cell surface receptors.The role of semaphorins and their receptors in vascular development and cancer.Navigation rules for vessels and neurons: cooperative signaling between VEGF and neural guidance cues.Recent molecular discoveries in angiogenesis and antiangiogenic therapies in cancerMonocyte chemoattractant protein-1 and the blood-brain barrier.Neuropilin regulation of angiogenesis, arteriogenesis, and vascular permeabilityNeuropilin-1 enforces extracellular matrix signalling via ABL1 to promote angiogenesis.Neuropilin regulation of angiogenesis.Angiogenesis versus arteriogenesis: neuropilin 1 modulation of VEGF signalingThe expanding role of neuropilin: regulation of transforming growth factor-β and platelet-derived growth factor signaling in the vasculatureAnti-angiogenic Therapy for Retinal Disease.The role of the semaphorins in cancer.LncRNA as a Therapeutic Target for Angiogenesis.Neuropilin-1 mediates vascular permeability independently of vascular endothelial growth factor receptor-2 activation.NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip Cells.Neuropilin 1 sequestration by neuropathogenic mutant glycyl-tRNA synthetase is permissive to vascular homeostasisA Hypothesis Concerning the Biphasic Dose-response of Tumors to Angiostatin and Endostatin.VEGF165-induced vascular permeability requires NRP1 for ABL-mediated SRC family kinase activation.Multifaceted Role of Neuropilins in the Immune System: Potential Targets for Immunotherapy
P2860
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P2860
The cytoplasmic domain of neuropilin 1 is dispensable for angiogenesis, but promotes the spatial separation of retinal arteries and veins
description
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2011
@ast
im Oktober 2011 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2011/10/01)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/10/01)
@nl
наукова стаття, опублікована в жовтні 2011
@uk
مقالة علمية (نشرت في أكتوبر 2011)
@ar
name
The cytoplasmic domain of neur ...... of retinal arteries and veins
@ast
The cytoplasmic domain of neur ...... of retinal arteries and veins
@en
The cytoplasmic domain of neur ...... of retinal arteries and veins
@nl
type
label
The cytoplasmic domain of neur ...... of retinal arteries and veins
@ast
The cytoplasmic domain of neur ...... of retinal arteries and veins
@en
The cytoplasmic domain of neur ...... of retinal arteries and veins
@nl
prefLabel
The cytoplasmic domain of neur ...... of retinal arteries and veins
@ast
The cytoplasmic domain of neur ...... of retinal arteries and veins
@en
The cytoplasmic domain of neur ...... of retinal arteries and veins
@nl
P2093
P2860
P356
P1433
P1476
The cytoplasmic domain of neur ...... of retinal arteries and veins
@en
P2093
Alessandro Fantin
Christiana Ruhrberg
Eduardo M. Normando
Kathryn Davidson
Laura Denti
Quenten Schwarz
P2860
P304
P356
10.1242/DEV.070037
P407
P577
2011-10-01T00:00:00Z