The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis
about
The histone demethylase Jarid1b ensures faithful mouse development by protecting developmental genes from aberrant H3K4me3Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortexTuning the cell fate of neurons and glia by microRNAsMolecular control of neurogenesis: a view from the mammalian cerebral cortexFrom trans to cis: transcriptional regulatory networks in neocortical developmentSustained Pax6 Expression Generates Primate-like Basal Radial Glia in Developing Mouse NeocortexTranscriptional Dynamics at Brain Enhancers: from Functional Specialization to NeurodegenerationFunctional dissection of the paired domain of Pax6 reveals molecular mechanisms of coordinating neurogenesis and proliferationHigh-throughput analysis of promoter occupancy reveals new targets for Arx, a gene mutated in mental retardation and interneuronopathiesThe protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate mapPax6 exerts regional control of cortical progenitor proliferation via direct repression of Cdk6 and hypophosphorylation of pRbThree Dimensional Human Neuro-Spheroid Model of Alzheimer's Disease Based on Differentiated Induced Pluripotent Stem CellsDownstream genes of Pax6 revealed by comprehensive transcriptome profiling in the developing rat hindbrainCoevolution of radial glial cells and the cerebral cortexCan a few non-coding mutations make a human brain?Mapping arealisation of the visual cortex of non-primate species: lessons for development and evolutionNeural progenitors, patterning and ecology in neocortical originsPax6-dependent cortical glutamatergic neuronal differentiation regulates autism-like behavior in prenatally valproic acid-exposed rat offspringXenopus pax6 mutants affect eye development and other organ systems, and have phenotypic similarities to human aniridia patients.Genome-wide microarray comparison reveals downstream genes of Pax6 in the developing mouse cerebellum.Understanding the evolution and development of neurosensory transcription factors of the ear to enhance therapeutic translation.Forced G1-phase reduction alters mode of division, neuron number, and laminar phenotype in the cerebral cortex.Uncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease.Direct reprogramming of Sertoli cells into multipotent neural stem cells by defined factors.Mouse strain specific gene expression differences for illumina microarray expression profiling in embryos.Clinical, genetic and imaging findings identify new causes for corpus callosum development syndromes.Lsh/HELLS regulates self-renewal/proliferation of neural stem/progenitor cells.Lacrimal Gland Repair Using Progenitor Cells.Drosophila Pax6 promotes development of the entire eye-antennal disc, thereby ensuring proper adult head formation.Shifts in the vascular endothelial growth factor isoforms result in transcriptome changes correlated with early neural stem cell proliferation and differentiation in mouse forebrain.The doublesex-related Dmrta2 safeguards neural progenitor maintenance involving transcriptional regulation of Hes1Transcriptional regulation of enhancers active in protodomains of the developing cerebral cortexDifferentiation of neuron-like cells from mouse parthenogenetic embryonic stem cells.Regulation of Pax6 by CTCF during induction of mouse ES cell differentiation.Activation of ERK by spontaneous seizures in neural progenitors of the dentate gyrus in a mouse model of epilepsyEpigenetic regulation of the neural transcriptome and alcohol interference during development.Expression of pax6 and sox2 in adult olfactory epithelium.PAX6 downregulates miR-124 expression to promote cell migration during embryonic stem cell differentiation.Notch signaling differentially regulates Atoh7 and Neurog2 in the distal mouse retina.MiR-135b is a direct PAX6 target and specifies human neuroectoderm by inhibiting TGF-β/BMP signaling.
P2860
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P2860
The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis
description
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
@ast
im Juni 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/06/01)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/06/01)
@nl
наукова стаття, опублікована в червні 2009
@uk
مقالة علمية (نشرت في يونيو 2009)
@ar
name
The level of the transcription ...... self-renewal and neurogenesis
@ast
The level of the transcription ...... self-renewal and neurogenesis
@en
The level of the transcription ...... self-renewal and neurogenesis
@nl
type
label
The level of the transcription ...... self-renewal and neurogenesis
@ast
The level of the transcription ...... self-renewal and neurogenesis
@en
The level of the transcription ...... self-renewal and neurogenesis
@nl
prefLabel
The level of the transcription ...... self-renewal and neurogenesis
@ast
The level of the transcription ...... self-renewal and neurogenesis
@en
The level of the transcription ...... self-renewal and neurogenesis
@nl
P2093
P2860
P50
P3181
P1433
P1476
The level of the transcription ...... self-renewal and neurogenesis
@en
P2093
Dean S. Griffiths
Dirk-Jan Kleinjan
Frederick J. Livesey
John L. Rubenstein
Stephen N. Sansom
Youlin Ruan
P2860
P304
P3181
P356
10.1371/JOURNAL.PGEN.1000511
P577
2009-06-01T00:00:00Z