Developmentally regulated role for Ras-GRFs in coupling NMDA glutamate receptors to Ras, Erk and CREB
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Imprinted Rasgrf1 expression in neonatal mice affects olfactory learning and memoryImprint switch mutations at Rasgrf1 support conflict hypothesis of imprinting and define a growth control mechanism upstream of IGF1The spread of Ras activity triggered by activation of a single dendritic spineRasGRF2, a guanosine nucleotide exchange factor for Ras GTPases, participates in T-cell signaling responsesThe NMDA receptor complex: a multifunctional machine at the glutamatergic synapseEarly mechanisms of pathobiology are revealed by transcriptional temporal dynamics in hippocampal CA1 neurons of prion infected miceKalirin binds the NR2B subunit of the NMDA receptor, altering its synaptic localization and functionLong-term potentiation in the CA1 hippocampus induced by NR2A subunit-containing NMDA glutamate receptors is mediated by Ras-GRF2/Erk map kinase signalingCabergoline, dopamine D2 receptor agonist, prevents neuronal cell death under oxidative stress via reducing excitotoxicitySCLIP, a microtubule-destabilizing factor, interacts with RasGRF1 and inhibits its ability to promote Rac activation and neurite outgrowthA Ras-induced conformational switch in the Ras activator Son of sevenlessNeural cell adhesion molecule-associated polysialic acid regulates synaptic plasticity and learning by restraining the signaling through GluN2B-containing NMDA receptors.Ras and Rap signaling in synaptic plasticity and mental disorders.State-dependent Ras signaling and AMPA receptor trafficking.Ras signaling mechanisms underlying impaired GluR1-dependent plasticity associated with fragile X syndrome.Synaptic plasticity, AMPA-R trafficking, and Ras-MAPK signaling.Neurotrophin-dependent tyrosine phosphorylation of Ras guanine-releasing factor 1 and associated neurite outgrowth is dependent on the HIKE domain of TrkA.Network-based empirical Bayes methods for linear models with applications to genomic data.Age-dependent role for Ras-GRF1 in the late stages of adult neurogenesis in the dentate gyrusDomain contributions to signaling specificity differences between Ras-guanine nucleotide releasing factor (Ras-GRF) 1 and Ras-GRF2Ras-GRF2 mediates long-term potentiation, survival, and response to an enriched environment of newborn neurons in the hippocampus.Meningococcal internalization into human endothelial and epithelial cells is triggered by the influx of extracellular L-glutamate via GltT L-glutamate ABC transporter in Neisseria meningitidisThe Ras-GRF1 exchange factor coordinates activation of H-Ras and Rac1 to control neuronal morphology.Switching of N-methyl-D-aspartate (NMDA) receptor-favorite intracellular signal pathways from ERK1/2 protein to p38 mitogen-activated protein kinase leads to developmental changes in NMDA neurotoxicityRegulation of Neuronal Function by Ras-GRF Exchange Factors.Targeted Sos1 deletion reveals its critical role in early T-cell development.Integration of biochemical signalling in spines.Activating Mutations Affecting the Dbl Homology Domain of SOS2 Cause Noonan Syndrome.A Single Nucleotide Polymorphism in the RASGRF2 Gene Is Associated with Alcoholic Liver Cirrhosis in Men.Ras family small GTPase-mediated neuroprotective signaling in stroke.Hereditary gingival fibromatosis: a systematic review.RASGRF2 regulates alcohol-induced reinforcement by influencing mesolimbic dopamine neuron activity and dopamine release.A translational systems biology approach in both animals and humans identifies a functionally related module of accumbal genes involved in the regulation of reward processing and binge drinking in males.Acquisition of contextual discrimination involves the appearance of a RAS-GRF1/p38 mitogen-activated protein (MAP) kinase-mediated signaling pathway that promotes long term potentiation (LTP)RasGRF2 Rac-GEF activity couples NMDA receptor calcium flux to enhanced synaptic transmission.Structural and spatial determinants regulating TC21 activation by RasGRF family nucleotide exchange factorsA single nucleotide polymorphism associated with reduced alcohol intake in the RASGRF2 gene predicts larger cortical volumes but faster longitudinal ventricular expansion in the elderly.Autophagy activated by tuberin/mTOR/p70S6K suppression is a protective mechanism against local anaesthetics neurotoxicity.Synaptic plasticity, a symphony in GEF.N-Methyl-D-Aspartate Receptor Signaling and Function in Cardiovascular Tissues
P2860
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P2860
Developmentally regulated role for Ras-GRFs in coupling NMDA glutamate receptors to Ras, Erk and CREB
description
2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
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im April 2004 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2004/04/07)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/04/07)
@nl
наукова стаття, опублікована у квітні 2004
@uk
مقالة علمية (نشرت في 7-4-2004)
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name
Developmentally regulated role ...... receptors to Ras, Erk and CREB
@ast
Developmentally regulated role ...... receptors to Ras, Erk and CREB
@en
Developmentally regulated role ...... receptors to Ras, Erk and CREB
@nl
type
label
Developmentally regulated role ...... receptors to Ras, Erk and CREB
@ast
Developmentally regulated role ...... receptors to Ras, Erk and CREB
@en
Developmentally regulated role ...... receptors to Ras, Erk and CREB
@nl
prefLabel
Developmentally regulated role ...... receptors to Ras, Erk and CREB
@ast
Developmentally regulated role ...... receptors to Ras, Erk and CREB
@en
Developmentally regulated role ...... receptors to Ras, Erk and CREB
@nl
P2093
P2860
P3181
P356
P1433
P1476
Developmentally regulated role ...... receptors to Ras, Erk and CREB
@en
P2093
Kiyoshi Tsuji
Larry A. Feig
Takaya Gotoh
Xuejun Tian
P2860
P304
P3181
P356
10.1038/SJ.EMBOJ.7600151
P407
P577
2004-04-07T00:00:00Z