The bile acid receptor GPBAR-1 (TGR5) modulates integrity of intestinal barrier and immune response to experimental colitis
about
Bile Acid Metabolism and Signaling in Cholestasis, Inflammation, and CancerRole of enteric neurotransmission in host defense and protection of the gastrointestinal tractControversies in the Mechanism of Total Parenteral Nutrition Induced PathologyBile acid metabolism and signalingBile acid signaling in metabolic disease and drug therapyFarnesoid X receptor: from medicinal chemistry to clinical applicationsCystic fibrosis related liver disease--another black box in hepatology.Commensal bacteria at the interface of host metabolism and the immune system.A GPBAR1 (TGR5) small molecule agonist shows specific inhibitory effects on myeloid cell activation in vitro and reduces experimental autoimmune encephalitis (EAE) in vivo.Bile acid dysregulation, gut dysbiosis, and gastrointestinal cancer.Oleanolic acid controls allergic and inflammatory responses in experimental allergic conjunctivitisTGR5 reduces macrophage migration through mTOR-induced C/EBPβ differential translationBile acid mediated effects on gut integrity and performance of early-weaned pigletsSystematic review: bile acids and intestinal inflammation-luminal aggressors or regulators of mucosal defence?Gut permeability, its interaction with gut microflora and effects on metabolic health are mediated by the lymphatics system, liver and bile acid.Urine and serum metabolomic profiling reveals that bile acids and carnitine may be potential biomarkers of primary biliary cirrhosis.An Integrated Multi-Omic Approach to Assess Radiation Injury on the Host-Microbiome Axis.Bile acid receptors as targets for the treatment of dyslipidemia and cardiovascular disease.The G-Protein-Coupled Bile Acid Receptor Gpbar1 (TGR5) Inhibits Gastric Inflammation Through Antagonizing NF-κB Signaling PathwayLithocholic acid controls adaptive immune responses by inhibition of Th1 activation through the Vitamin D receptor.Bile Acid Receptors and Liver Cancer.Gustducin couples fatty acid receptors to GLP-1 release in colon.The solute carrier family 10 (SLC10): beyond bile acid transportTGR5 signalling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's diseaseMechanisms of oxysterol-induced disease: insights from the biliary system.Dissociation of intestinal and hepatic activities of FXR and LXRα supports metabolic effects of terminal ileum interposition in rodents.The Gut Microbiota as a Therapeutic Target in IBD and Metabolic Disease: A Role for the Bile Acid Receptors FXR and TGR5.Xenobiotic Receptor-Mediated Regulation of Intestinal Barrier Function and Innate Immunity.Bile acid receptors in non-alcoholic fatty liver disease.A Disease-Associated Microbial and Metabolomics State in Relatives of Pediatric Inflammatory Bowel Disease Patients.GPBA: a GPCR for bile acids and an emerging therapeutic target for disorders of digestion and sensation.The bile acid receptor GPBAR1 (TGR5) is expressed in human gastric cancers and promotes epithelial-mesenchymal transition in gastric cancer cell lines.5β-Reduced steroids and human Δ(4)-3-ketosteroid 5β-reductase (AKR1D1).Digestive physiology of the pig symposium: intestinal bile acid sensing is linked to key endocrine and metabolic signaling pathways.The bile acid membrane receptor TGR5: a novel pharmacological target in metabolic, inflammatory and neoplastic disorders.The bile acid TGR5 membrane receptor: from basic research to clinical application.TGR5 in inflammation and cardiovascular disease.The role of bile acids in functional GI disorders.TGR5: pathogenetic role and/or therapeutic target in fibrosing cholangitis?Bile acid malabsorption in inflammatory bowel disease.
P2860
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P2860
The bile acid receptor GPBAR-1 (TGR5) modulates integrity of intestinal barrier and immune response to experimental colitis
description
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique PLoS ONE
@fr
artículu científicu espublizáu en 2011
@ast
im Januar 2011 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2011/01/01)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/01/01)
@nl
наукова стаття, опублікована в січні 2011
@uk
name
The bile acid receptor GPBAR-1 ...... sponse to experimental colitis
@ast
The bile acid receptor GPBAR-1 ...... sponse to experimental colitis
@en
The bile acid receptor GPBAR-1 ...... sponse to experimental colitis
@nl
type
label
The bile acid receptor GPBAR-1 ...... sponse to experimental colitis
@ast
The bile acid receptor GPBAR-1 ...... sponse to experimental colitis
@en
The bile acid receptor GPBAR-1 ...... sponse to experimental colitis
@nl
prefLabel
The bile acid receptor GPBAR-1 ...... sponse to experimental colitis
@ast
The bile acid receptor GPBAR-1 ...... sponse to experimental colitis
@en
The bile acid receptor GPBAR-1 ...... sponse to experimental colitis
@nl
P2093
P2860
P3181
P1433
P1476
The bile acid receptor GPBAR-1 ...... sponse to experimental colitis
@en
P2093
Andrea Mencarelli
Annibale Donini
Barbara Renga
Eleonora Distrutti
Franco Baldelli
Giuseppe Bifulco
Maria Giovanna Chini
Sabrina Cipriani
Stefano Fiorucci
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0025637
P407
P577
2011-01-01T00:00:00Z