Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5
about
Myocyte enhancer factor 2C and Nkx2-5 up-regulate each other's expression and initiate cardiomyogenesis in P19 cellsIdentification of the in vivo casein kinase II phosphorylation site within the homeodomain of the cardiac tisue-specifying homeobox gene product Csx/Nkx2.5Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathwaysCardiovascular basic helix loop helix factor 1, a novel transcriptional repressor expressed preferentially in the developing and adult cardiovascular systemFunctional analyses of three Csx/Nkx-2.5 mutations that cause human congenital heart diseaseChoreoathetosis, hypothyroidism, and pulmonary alterations due to human NKX2-1 haploinsufficiencyCsx/Nkx2-5 is required for homeostasis and survival of cardiac myocytes in the adult heartThe double-histone-acetyltransferase complex ATAC is essential for mammalian developmentThe cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors.Recruitment of the tinman homolog Nkx-2.5 by serum response factor activates cardiac alpha-actin gene transcriptionMolecular cloning, chromosomal mapping, and characterization of the human cardiac-specific homeobox gene hCsxCongenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 moduleA novel nk-2-related transcription factor associated with human fetal liver and hepatocellular carcinomaRegulation of cardiac specific nkx2.5 gene activity by small ubiquitin-like modifierInactivation of the Sema5a gene results in embryonic lethality and defective remodeling of the cranial vascular systemThe Polycomb-group gene Rae28 sustains Nkx2.5/Csx expression and is essential for cardiac morphogenesisBone morphogenetic proteins induce cardiomyocyte differentiation through the mitogen-activated protein kinase kinase kinase TAK1 and cardiac transcription factors Csx/Nkx-2.5 and GATA-4Loss of function and inhibitory effects of human CSX/NKX2.5 homeoprotein mutations associated with congenital heart diseaseCooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: implications for cardiac chamber formationA novel LIM protein Cal promotes cardiac differentiation by association with CSX/NKX2-5The ETS Factor, ETV2: a Master Regulator for Vascular Endothelial Cell DevelopmentUpdate on the Pathogenic Implications and Clinical Potential of microRNAs in Cardiac DiseaseDevelopments in our understanding of the genetic basis of birth defectsXin proteins and intercalated disc maturation, signaling and diseasesOf mice and men: molecular genetics of congenital heart diseaseCiona as a Simple Chordate Model for Heart Development and RegenerationArrhythmia caused by a Drosophila tropomyosin mutation is revealed using a novel optical coherence tomography instrumentCrystal Structure of the Human NKX2.5 Homeodomain in Complex with DNA TargetDevelopment of the endocardium.An Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferation.A regulatory pathway involving Notch1/beta-catenin/Isl1 determines cardiac progenitor cell fate.JUMONJI, a critical factor for cardiac development, functions as a transcriptional repressorThe DNA glycosylase T:G mismatch-specific thymine DNA glycosylase represses thyroid transcription factor-1-activated transcriptionLocalization of the novel Xin protein to the adherens junction complex in cardiac and skeletal muscle during developmentElements regulating cardiomyocyte expression of the human sarcomeric mitochondrial creatine kinase gene in transgenic miceProteasome-mediated degradation of the coactivator p300 impairs cardiac transcriptionAltered molecular response to adrenoreceptor-induced cardiac hypertrophy in Egr-1-deficient miceComplex SUMO-1 regulation of cardiac transcription factor Nkx2-5Congenital heart disease-causing Gata4 mutation displays functional deficits in vivoDistinct gene expression patterns in skeletal and cardiac muscle are dependent on common regulatory sequences in the MLC1/3 locus
P2860
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P2860
Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5
description
1995 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1995
@ast
im Juli 1995 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1995/07/01)
@sk
vědecký článek publikovaný v roce 1995
@cs
wetenschappelijk artikel (gepubliceerd op 1995/07/01)
@nl
наукова стаття, опублікована в липні 1995
@uk
مقالة علمية (نشرت في يوليو 1995)
@ar
name
Myogenic and morphogenetic def ...... king the homeo box gene Nkx2-5
@ast
Myogenic and morphogenetic def ...... king the homeo box gene Nkx2-5
@en
Myogenic and morphogenetic def ...... king the homeo box gene Nkx2-5
@nl
type
label
Myogenic and morphogenetic def ...... king the homeo box gene Nkx2-5
@ast
Myogenic and morphogenetic def ...... king the homeo box gene Nkx2-5
@en
Myogenic and morphogenetic def ...... king the homeo box gene Nkx2-5
@nl
prefLabel
Myogenic and morphogenetic def ...... king the homeo box gene Nkx2-5
@ast
Myogenic and morphogenetic def ...... king the homeo box gene Nkx2-5
@en
Myogenic and morphogenetic def ...... king the homeo box gene Nkx2-5
@nl
P2093
P3181
P356
P1433
P1476
Myogenic and morphogenetic def ...... king the homeo box gene Nkx2-5
@en
P2093
P304
P3181
P356
10.1101/GAD.9.13.1654
P577
1995-07-01T00:00:00Z