Modulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extension
about
Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cellsAbl kinase interacts with and phosphorylates vinexinABL tyrosine kinases: evolution of function, regulation, and specificityProtein kinase MARK/PAR-1 is required for neurite outgrowth and establishment of neuronal polarity.c-Abl phosphorylates α-synuclein and regulates its degradation: implication for α-synuclein clearance and contribution to the pathogenesis of Parkinson's diseaseRegulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contextsGleevec, an Abl family inhibitor, produces a profound change in cell shape and migrationDok-R binds c-Abl and regulates Abl kinase activity and mediates cytoskeletal reorganizationUnc119 protects from Shigella infection by inhibiting the Abl family kinasesc-Abl promotes osteoblast expansion by differentially regulating canonical and non-canonical BMP pathways and p16INK4a expressionc-Abl phosphorylates Dok1 to promote filopodia during cell spreadingAbl silencing inhibits CAS-mediated process and constriction in resistance arteriesSynaptic clustering of PSD-95 is regulated by c-Abl through tyrosine phosphorylationArg interacts with cortactin to promote adhesion-dependent cell edge protrusionc-Abl, Lamellipodin, and Ena/VASP proteins cooperate in dorsal ruffling of fibroblasts and axonal morphogenesisABL1 in thalamus is associated with safety but not fear learningAvian influenza viruses inhibit the major cellular signalling integrator c-Abl.The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages.c-Abl tyrosine kinase plays a critical role in β2 integrin-dependent neutrophil migration by regulating Vav1 activity.Functional mechanisms and roles of adaptor proteins in abl-regulated cytoskeletal actin dynamics.Abl kinase constructs expressed in bacteria: facilitation of structural and functional studies including segmental labeling by expressed protein ligationA crucial role in cell spreading for the interaction of Abl PxxP motifs with Crk and Nck adaptors.Mitotic phosphorylation rescues Abl from F-actin-mediated inhibition.Abl tyrosine kinase promotes dorsal ruffles but restrains lamellipodia extension during cell spreading on fibronectin.Integrin signaling through Arg activates p190RhoGAP by promoting its binding to p120RasGAP and recruitment to the membrane.The Abl-related gene tyrosine kinase acts through p190RhoGAP to inhibit actomyosin contractility and regulate focal adhesion dynamics upon adhesion to fibronectinUsing Bcr-Abl to examine mechanisms by which abl kinase regulates morphogenesis in Drosophila.Abl tyrosine kinase phosphorylates nonmuscle Myosin light chain kinase to regulate endothelial barrier functionIn the absence of frazzled over-expression of Abelson tyrosine kinase disrupts commissure formation and causes axons to leave the embryonic CNS.A non-Smad mechanism of fibroblast activation by transforming growth factor-beta via c-Abl and Egr-1: selective modulation by imatinib mesylate.Activated Abl kinase inhibits oncogenic transforming growth factor-beta signaling and tumorigenesis in mammary tumors.c-Abl mediates endothelial apoptosis induced by inhibition of integrins alphavbeta3 and alphavbeta5 and by disruption of actin.c-Abl is an upstream regulator of acid sphingomyelinase in apoptosis induced by inhibition of integrins αvβ3 and αvβ5.Spatial phosphoprotein profiling reveals a compartmentalized extracellular signal-regulated kinase switch governing neurite growth and retractionAntimitotic chemotherapeutics promote adhesive responses in detached and circulating tumor cellsSite-specific hyperphosphorylation of pRb in HIV-induced neurotoxicity.Itk: the rheostat of the T cell response.Do filopodia enable the growth cone to find its way?Role of zinc metallothionein-3 (ZnMt3) in epidermal growth factor (EGF)-induced c-Abl protein activation and actin polymerization in cultured astrocytes.Controlling Abl: auto-inhibition and co-inhibition?
P2860
Q21195236-43897988-08B4-4C92-96FE-AA5274ACEAF5Q24296684-12B413CC-A002-4734-B5E7-78834683A3B8Q24299738-0A7D378A-48FF-4AED-8A57-10EB4146FAB8Q24317775-3BCE984F-3791-441C-980A-94F6F9324820Q24318974-9A20120B-4B8E-497B-AD34-229641C4F96CQ24652254-F5D08F53-CFCC-4E68-9DC9-0AE9D0D9C30FQ27325747-84B63B29-902A-4798-86B0-774FAA165220Q28207727-D316E143-A6C9-4CD1-8056-AE3AA04A4DD5Q28475302-611CEF8A-E346-482D-B6EE-8EFA5F39574CQ28504995-8192BE08-6C78-4008-894C-E9555F2DFAD5Q28510526-946721C1-3513-4850-9FA5-504BA9C8D7DEQ28565734-61859739-A33F-4D8E-BCBB-9075CA209A83Q28581044-C1622E8B-B1EE-48C4-8A7B-2B8B9E59FC46Q28585696-4D84665D-9BF1-4CE4-B950-A16AF8E29895Q28589079-36073098-0D74-4B68-B792-EE232187A44DQ29347034-4C58F9C7-C0BB-4002-813D-C0C75CE1E6A5Q30009343-80305B41-301F-493E-9C47-D896DDC364F9Q30009552-4462E440-D70A-4641-88B7-7E34897355E5Q30009942-43A1062E-A877-4E81-81FF-4EE30428D5EFQ30010077-0E2AF4E2-3D33-4B24-867A-D736A4F81155Q30010105-4DF800F0-9889-4636-8AFC-169AA9E41FBEQ30157529-AECC236C-ABF4-4D14-BFA8-2A8925C615CCQ30160360-9F36A0A9-70CC-4EE7-A5D4-33563E957D6CQ30444235-788260C2-80F7-4C19-94FD-A06A449F5879Q30445496-7CE8C796-8531-4D6C-B09B-DEFD8E975312Q30480147-9C29B7C7-FC0C-4D53-B0A0-8A1BE5D11055Q30480984-DD7436D4-C4CC-434D-ACEA-A14BE45FE442Q30497383-92D5B443-FE35-4CE0-83B5-C5F60E648217Q33547449-F82E30DB-02B6-4B86-BF00-2A7E75EB610DQ33551475-266937BF-A07E-4BB1-AE2F-685E0C635068Q33613286-AA71D693-00B3-4114-A829-9DC594A592E1Q33780290-7BF3BD62-63B1-4D5A-898D-23FD1ED02105Q34374088-2AA41DE3-4C88-4729-95DE-F0709D472F31Q34979113-948B9B4C-201E-479E-8A6F-402BB3CA78D7Q34991861-EF82BE2B-BC40-4B36-BFE3-F9BCB1A37C0FQ34995472-F6863FDF-48EE-4498-9D21-CCE6F346BAE8Q35049534-BA287F5B-854C-4ABE-915B-0E5D58173828Q35132220-09EBA155-2FA7-46F0-BE4B-DA7791764FB7Q35562577-8B8E7924-B250-4FC7-B55E-E7F09F631C13Q35620042-0B28920E-5F6F-4166-8957-69F94D539A81
P2860
Modulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extension
description
2002 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
@ast
im März 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/03/04)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/03/04)
@nl
наукова стаття, опублікована в березні 2002
@uk
مقالة علمية (نشرت في 4-3-2002)
@ar
name
Modulation of the F-actin cyto ...... preading and neurite extension
@ast
Modulation of the F-actin cyto ...... preading and neurite extension
@en
Modulation of the F-actin cyto ...... preading and neurite extension
@nl
type
label
Modulation of the F-actin cyto ...... preading and neurite extension
@ast
Modulation of the F-actin cyto ...... preading and neurite extension
@en
Modulation of the F-actin cyto ...... preading and neurite extension
@nl
prefLabel
Modulation of the F-actin cyto ...... preading and neurite extension
@ast
Modulation of the F-actin cyto ...... preading and neurite extension
@en
Modulation of the F-actin cyto ...... preading and neurite extension
@nl
P2093
P2860
P921
P356
P1476
Modulation of the F-actin cyto ...... preading and neurite extension
@en
P2093
Dennis D. M. O'Leary
E. David Litwack
Ginger R. Lucero
Jean Y. J. Wang
Pamela J. Woodring
Tony Hunter
P2860
P304
P356
10.1083/JCB.200110014
P407
P577
2002-03-04T00:00:00Z