Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression
about
Mst1 and Mst2 kinases: regulations and diseasesYap1 acts downstream of α-catenin to control epidermal proliferationMST1 is a multifunctional caspase-independent inhibitor of androgenic signaling.Mammalian MST2 kinase and human Salvador activate and reduce estrogen receptor alpha in the absence of ligandMICAL-1 is a negative regulator of MST-NDR kinase signaling and apoptosisThe tumor suppressor Mst1 promotes changes in the cellular redox state by phosphorylation and inactivation of peroxiredoxin-1 proteinThe tumor suppressor RASSF1A prevents dephosphorylation of the mammalian STE20-like kinases MST1 and MST2.Angiomotin is a novel Hippo pathway component that inhibits YAP oncoproteinGenetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAPThe hippo signaling pathway in development and cancerα-catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1The Roles of NDR Protein Kinases in Hippo SignallingMechanisms of Hippo pathway regulationHepatocellular carcinoma mouse models: Hepatitis B virus-associated hepatocarcinogenesis and haploinsufficient tumor suppressor genesEmerging role of Hippo pathway in gastric and other gastrointestinal cancersMST kinases in development and diseaseMammalian Hippo signalling: a kinase network regulated by protein-protein interactionsThe two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatmentFunctional role of Mst1/Mst2 in embryonic stem cell differentiationNDR Kinases Are Essential for Somitogenesis and Cardiac Looping during Mouse Embryonic DevelopmentComparative study of Hippo pathway genes in cellular conveyor belts of a ctenophore and a cnidarian.Seed Sequence-Matched Controls Reveal Limitations of Small Interfering RNA Knockdown in Functional and Structural Studies of Hepatitis C Virus NS5A-MOBKL1B InteractionTargeting the Hippo Signaling Pathway for Tissue Regeneration and Cancer TherapyRegulation of Long Bone Growth in Vertebrates; It Is Time to Catch UpEmerging evidence on the role of the Hippo/YAP pathway in liver physiology and cancerHippo Pathway in Organ Size Control, Tissue Homeostasis, and CancerThe Hippo-YAP pathway in organ size control and tumorigenesis: an updated versionCharacterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian developmentAblation of Rassf2 induces bone defects and subsequent haematopoietic anomalies in miceActin cytoskeleton regulates Hippo signalingMst1 and mst2 are essential regulators of trophoblast differentiation and placenta morphogenesisA cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesisE-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components.The Hippo signaling pathway in stem cell biology and cancerYap1 protein regulates vascular smooth muscle cell phenotypic switch by interaction with myocardin.What do mechanotransduction, Hippo, Wnt, and TGFβ have in common? YAP and TAZ as key orchestrating molecules in ocular health and disease.The NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex.The role of the Hippo pathway in human disease and tumorigenesisTumor suppressor Hippo/MST1 kinase mediates chemotaxis by regulating spreading and adhesionCytokinesis involves a nontranscriptional function of the Hippo pathway effector YAP.
P2860
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P2860
Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression
description
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2010
@ast
im Januar 2010 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2010/01/26)
@sk
vědecký článek publikovaný v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/01/26)
@nl
наукова стаття, опублікована в січні 2010
@uk
name
Mammalian Mst1 and Mst2 kinase ...... control and tumor suppression
@ast
Mammalian Mst1 and Mst2 kinase ...... control and tumor suppression
@en
Mammalian Mst1 and Mst2 kinase ...... control and tumor suppression
@nl
type
label
Mammalian Mst1 and Mst2 kinase ...... control and tumor suppression
@ast
Mammalian Mst1 and Mst2 kinase ...... control and tumor suppression
@en
Mammalian Mst1 and Mst2 kinase ...... control and tumor suppression
@nl
prefLabel
Mammalian Mst1 and Mst2 kinase ...... control and tumor suppression
@ast
Mammalian Mst1 and Mst2 kinase ...... control and tumor suppression
@en
Mammalian Mst1 and Mst2 kinase ...... control and tumor suppression
@nl
P2093
P2860
P921
P3181
P356
P1476
Mammalian Mst1 and Mst2 kinase ...... control and tumor suppression
@en
P2093
Cun-Yu Wang
Jianxin Hu
Kangsun Yun
Kinglun Kingston Mak
Lilia Topol
Lisa Garrett
P2860
P304
P3181
P356
10.1073/PNAS.0911409107
P407
P577
2010-01-26T00:00:00Z