p63 null mutation protects mouse oocytes from radio-induced apoptosis
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Cables1 protects p63 from proteasomal degradation to ensure deletion of cells after genotoxic stressProliferating cell nuclear antigen (PCNA) regulates primordial follicle assembly by promoting apoptosis of oocytes in fetal and neonatal mouse ovariesImplementation of meiosis prophase I programme requires a conserved retinoid-independent stabilizer of meiotic transcriptsPrevention of chemotherapy-induced ovarian damage: possible roles for hormonal and non-hormonal attenuating agentsReversal of female infertility by Chk2 ablation reveals the oocyte DNA damage checkpoint pathwayThe Src homology 2 domain-containing adapter protein B (SHB) regulates mouse oocyte maturationOocyte-specific inactivation of Omcg1 leads to DNA damage and c-Abl/TAp63-dependent oocyte death associated with dramatic remodeling of ovarian somatic cellsOCT4 as a target of miR-34a stimulates p63 but inhibits p53 to promote human cell transformation.Melatonin and Fertoprotective Adjuvants: Prevention against Premature Ovarian Failure during Chemotherapy.The role of p53 gene family in reproduction.Regulation of Caenorhabditis elegans p53/CEP-1-dependent germ cell apoptosis by Ras/MAPK signaling.Bioinformatics study of cancer-related mutations within p53 phosphorylation site motifsTamoxifen decreases ovarian follicular loss from experimental toxicant DMBA and chemotherapy agents cyclophosphamide and doxorubicin in the rat.DNA double strand breaks but not interstrand crosslinks prevent progress through meiosis in fully grown mouse oocytes.Fertility preservation in women with cancer.Cisplatin and doxorubicin induce distinct mechanisms of ovarian follicle loss; imatinib provides selective protection only against cisplatinPoly (C)-binding protein 1 regulates p63 expression through mRNA stability.Regulation of Fertility by the p53 Family Members.Pathway Regulation of p63, a Director of Epithelial Cell FateDNA damage induces a meiotic arrest in mouse oocytes mediated by the spindle assembly checkpoint.DNA damage-induced primordial follicle oocyte apoptosis and loss of fertility require TAp63-mediated induction of Puma and NoxaQuality control in oocytes by p63 is based on a spring-loaded activation mechanism on the molecular and cellular level.The DNA damage response in mammalian oocytes.Rescue of platinum-damaged oocytes from programmed cell death through inactivation of the p53 family signaling networkFemale mice with loss-of-function ITCH display an altered reproductive phenotypeThe alpha/beta carboxy-terminal domains of p63 are required for skin and limb development. New insights from the Brdm2 mouse which is not a complete p63 knockout but expresses p63 gamma-like proteinsLH prevents cisplatin-induced apoptosis in oocytes and preserves female fertility in mouse.Defying DNA double-strand break-induced death during prophase I meiosis by temporal TAp63α phosphorylation regulation in developing mouse oocytes.The role of p63 in cancer, stem cells and cancer stem cells.Cisplatin-induced primordial follicle oocyte killing and loss of fertility are not prevented by imatinib.Preserving fertility during cancer treatment.How to best preserve oocytes in female cancer patients exposed to DNA damage inducing therapeutics.Control mechanisms in germ cells mediated by p53 family proteins.Doxorubicin-induced female reproductive toxicity: an assessment of ovarian follicular apoptosis, cyclicity and reproductive tissue histology in Wistar rats.Pharmacological Inhibition of the DNA Damage Checkpoint Prevents Radiation-Induced Oocyte Death.Loss of oocytes due to conditional ablation of Murine double minute 2 (Mdm2) gene is p53-dependent and results in female sterility.Transcriptional regulation of P63 on the apoptosis of male germ cells and three stages of spermatogenesis in mice.Loss of PUMA protects the ovarian reserve during DNA-damaging chemotherapy and preserves fertility.C-Abl is not actıvated in DNA damage-induced and Tap63-mediated oocyte apoptosıs in human ovary
P2860
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P2860
p63 null mutation protects mouse oocytes from radio-induced apoptosis
description
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im Januar 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/01/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/01/01)
@nl
наукова стаття, опублікована в січні 2008
@uk
مقالة علمية (نشرت عام 2008)
@ar
name
p63 null mutation protects mouse oocytes from radio-induced apoptosis
@ast
p63 null mutation protects mouse oocytes from radio-induced apoptosis
@en
p63 null mutation protects mouse oocytes from radio-induced apoptosis
@nl
type
label
p63 null mutation protects mouse oocytes from radio-induced apoptosis
@ast
p63 null mutation protects mouse oocytes from radio-induced apoptosis
@en
p63 null mutation protects mouse oocytes from radio-induced apoptosis
@nl
prefLabel
p63 null mutation protects mouse oocytes from radio-induced apoptosis
@ast
p63 null mutation protects mouse oocytes from radio-induced apoptosis
@en
p63 null mutation protects mouse oocytes from radio-induced apoptosis
@nl
P2093
P3181
P356
P1433
P1476
p63 null mutation protects mouse oocytes from radio-induced apoptosis
@en
P2093
Béatrice Petre-Lazar
Emilie Trautmann
Hervé Coffigny
Marie-Justine Guerquin
René Habert
P3181
P356
10.1530/REP-07-0054
P577
2008-01-01T00:00:00Z