Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mice.
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Rad GTPase deficiency leads to cardiac hypertrophyKruppel-like factor 15 is a regulator of cardiomyocyte hypertrophy.Paxillin and Focal Adhesion Kinase (FAK) Regulate Cardiac Contractility in the Zebrafish HeartCardiac-myocyte-specific excision of the vinculin gene disrupts cellular junctions, causing sudden death or dilated cardiomyopathySerine-910 phosphorylation of focal adhesion kinase is critical for sarcomere reorganization in cardiomyocyte hypertrophyFocal adhesion kinase as a RhoA-activable signaling scaffold mediating Akt activation and cardiomyocyte protectionBeta1-adrenergic receptors promote focal adhesion signaling downregulation and myocyte apoptosis in acute volume overload.C3G overexpression promotes the survival of rat-derived H9C2 cardiomyocytes by p-ERK1/2.Myocyte-restricted focal adhesion kinase deletion attenuates pressure overload-induced hypertrophyFocal adhesion kinase and endothelial cell apoptosis.Integrins and integrin-associated proteins in the cardiac myocyte.Evidence for calreticulin attenuation of cardiac hypertrophy induced by pressure overload and soluble agonists.Significance of thymosin β4 and implication of PINCH-1-ILK-α-parvin (PIP) complex in human dilated cardiomyopathyFocal adhesion kinase antagonizes doxorubicin cardiotoxicity via p21(Cip1.).Chymase inhibition prevents fibronectin and myofibrillar loss and improves cardiomyocyte function and LV torsion angle in dogs with isolated mitral regurgitation.Sympathetic activation causes focal adhesion signaling alteration in early compensated volume overload attributable to isolated mitral regurgitation in the dog.Vinculin and talin: focus on the myocardiumInhibition of podocyte FAK protects against proteinuria and foot process effacement.Cardioplegic strategies to protect the hypertrophic heart during cardiac surgery.Focal adhesion kinase-promoted tumor glucose metabolism is associated with a shift of mitochondrial respiration to glycolysis.Mechanotransduction Mechanisms for Intraventricular Diastolic Vortex Forces and Myocardial Deformations: Part 2.β1 integrin gene excision in the adult murine cardiac myocyte causes defective mechanical and signaling responses.Stretch-induced MAP kinase activation in cardiac myocytes: differential regulation through beta1-integrin and focal adhesion kinaseCardiac developmental defects and eccentric right ventricular hypertrophy in cardiomyocyte focal adhesion kinase (FAK) conditional knockout miceSTIM1-dependent Ca(2+) microdomains are required for myofilament remodeling and signaling in the heart.Disruption of mindin exacerbates cardiac hypertrophy and fibrosis.Inactivation of FIP200 leads to inflammatory skin disorder, but not tumorigenesis, in conditional knock-out mouse models.The role of Neuregulin-1beta/ErbB signaling in the heart.The costamere bridges sarcomeres to the sarcolemma in striated muscle.B-type natriuretic peptide and extracellular matrix protein interactions in human cardiac fibroblasts.Focal adhesion kinase signaling in cardiac hypertrophy and failure.Deep sequence analysis of gene expression identifies osteopontin as a downstream effector of integrin-linked kinase (ILK) in cardiac-specific ILK knockout miceMechanical stress-induced sarcomere assembly for cardiac muscle growth in length and width.Gene expression patterns in transgenic mouse models of hypertrophic cardiomyopathy caused by mutations in myosin regulatory light chain.Cardiotoxicity of kinase inhibitors: the prediction and translation of preclinical models to clinical outcomes.Targeting focal adhesion kinase in fibrotic diseases.Focal adhesion signaling in heart failureThe multiple mechanistic faces of a pure volume overload: implications for therapyThe (dys)functional extracellular matrix.Integrin-FAK signaling rapidly and potently promotes mitochondrial function through STAT3
P2860
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P2860
Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mice.
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Inactivation of focal adhesion ...... pertrophy and fibrosis in mice
@nl
Inactivation of focal adhesion ...... ertrophy and fibrosis in mice.
@ast
Inactivation of focal adhesion ...... ertrophy and fibrosis in mice.
@en
type
label
Inactivation of focal adhesion ...... pertrophy and fibrosis in mice
@nl
Inactivation of focal adhesion ...... ertrophy and fibrosis in mice.
@ast
Inactivation of focal adhesion ...... ertrophy and fibrosis in mice.
@en
prefLabel
Inactivation of focal adhesion ...... pertrophy and fibrosis in mice
@nl
Inactivation of focal adhesion ...... ertrophy and fibrosis in mice.
@ast
Inactivation of focal adhesion ...... ertrophy and fibrosis in mice.
@en
P2093
P2860
P3181
P356
P1476
Inactivation of focal adhesion ...... ertrophy and fibrosis in mice.
@en
P2093
Ana Alcaraz
Guangju Ji
Huijun Wei
Jun-Lin Guan
Kenneth Chien
Lihong Cheng
Marc S Kraus
Michael I Kotlikoff
P2860
P304
P3181
P356
10.1172/JCI24497
P407
P577
2005-12-22T00:00:00Z