Spatial distribution and functional significance of activated vinculin in living cells
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Vinculin regulates cell-surface E-cadherin expression by binding to beta-cateninCAP interacts with cytoskeletal proteins and regulates adhesion-mediated ERK activation and motilityVinculin and metavinculin: oligomerization and interactions with F-actinDimer asymmetry defines α-catenin interactionsCardiac-myocyte-specific excision of the vinculin gene disrupts cellular junctions, causing sudden death or dilated cardiomyopathyPaxillin and Hic-5 interaction with vinculin is differentially regulated by Rac1 and RhoAMeasuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics.Spider Silk Peptide Is a Compact, Linear Nanospring Ideal for Intracellular Tension Sensing.Vinculin controls focal adhesion formation by direct interactions with talin and actin.Regulation of cell motile behavior by crosstalk between cadherin- and integrin-mediated adhesions.Activation of vinculin induced by cholinergic stimulation regulates contraction of tracheal smooth muscle tissue.Cooperative Vinculin Binding to Talin Mapped by Time-Resolved Super Resolution Microscopy.Focal adhesion plaque associated cytoskeletons are involved in the invasion and metastasis of human colorectal carcinoma.Nanoscale architecture of cadherin-based cell adhesions.Calpain- and talin-dependent control of microvascular pericyte contractility and cellular stiffness.Vinculin in cell-cell and cell-matrix adhesions.Monomeric and dimeric conformation of the vinculin tail five-helix bundle in solution studied by EPR spectroscopy.A molecular dynamics investigation of vinculin activation.Survival motor neuron protein deficiency impairs myotube formation by altering myogenic gene expression and focal adhesion dynamics.Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate.Mammary gland ECM remodeling, stiffness, and mechanosignaling in normal development and tumor progressionVinculin activation is necessary for complete talin bindingForcing a connection: impacts of single-molecule force spectroscopy on in vivo tension sensing.Down-regulation of vinculin upon MK886-induced apoptosis in LN18 glioblastoma cellsProtein tethering into multiscale geometries by covalent subtractive printing.Vinculin activators target integrins from within the cell to increase melanoma sensitivity to chemotherapy.HAb18G/CD147 regulates vinculin-mediated focal adhesion and cytoskeleton organization in cultured human hepatocellular carcinoma cells.New insights into vinculin function and regulation.Vinculin motion modes analysis with elastic network model.α-Catenin uses a novel mechanism to activate vinculin.Molecular mechanism of vinculin activation and nanoscale spatial organization in focal adhesions.Multiscale modeling of form and functionShigella applies molecular mimicry to subvert vinculin and invade host cells.Vinculin association with actin cytoskeleton is necessary for stiffness-dependent regulation of vinculin behavior.Nanopatterning reveals an ECM area threshold for focal adhesion assembly and force transmission that is regulated by integrin activation and cytoskeleton tension.The Structural Basis of Actin Organization by Vinculin and MetavinculinPushing, pulling, and squeezing our way to understanding mechanotransductionHow vinculin regulates force transmission.Lipid binding to the tail domain of vinculin: specificity and the role of the N and C termini.Visualizing and quantifying adhesive signals.
P2860
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P2860
Spatial distribution and functional significance of activated vinculin in living cells
description
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im Mai 2005 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2005/05/09)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/05/09)
@nl
наукова стаття, опублікована в травні 2005
@uk
مقالة علمية (نشرت في 9-5-2005)
@ar
name
Spatial distribution and functional significance of activated vinculin in living cells
@ast
Spatial distribution and functional significance of activated vinculin in living cells
@en
Spatial distribution and functional significance of activated vinculin in living cells
@nl
type
label
Spatial distribution and functional significance of activated vinculin in living cells
@ast
Spatial distribution and functional significance of activated vinculin in living cells
@en
Spatial distribution and functional significance of activated vinculin in living cells
@nl
prefLabel
Spatial distribution and functional significance of activated vinculin in living cells
@ast
Spatial distribution and functional significance of activated vinculin in living cells
@en
Spatial distribution and functional significance of activated vinculin in living cells
@nl
P2093
P2860
P356
P1476
Spatial distribution and functional significance of activated vinculin in living cells
@en
P2093
Dilshad M Choudhury
Noriyuki Kioka
Susan W Craig
P2860
P304
P356
10.1083/JCB.200410100
P407
P577
2005-05-01T00:00:00Z