Effect of conditional knockout of the type II TGF-beta receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasis
about
Lack of transforming growth factor-β signaling promotes collective cancer cell invasion through tumor-stromal crosstalk.14-3-3ζ turns TGF-β's function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of Smad partners from p53 to Gli2Single and Multiple Gene Manipulations in Mouse Models of Human CancerTargeting TGF-β signaling in cancerComplexities of TGF-β targeted cancer therapy.Switching Roles of TGF-β in Cancer Development: Implications for Therapeutic Target and Biomarker StudiesTGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4TGFbeta in CancerAttenuated transforming growth factor beta signaling promotes metastasis in a model of HER2 mammary carcinogenesisRole of TGF-β signaling in generation of CD39+CD73+ myeloid cells in tumorsLoss of TGFbeta signaling destabilizes homeostasis and promotes squamous cell carcinomas in stratified epithelia.Stromally derived lysyl oxidase promotes metastasis of transforming growth factor-β-deficient mouse mammary carcinomasDefective TGF-β signaling in bone marrow-derived cells prevents hedgehog-induced skin tumors.Heterogeneity of mammary lesions represent molecular differencesTGF-β signaling in myeloid cells is required for tumor metastasis.Association between TGFBR1*6A and osteosarcoma: a Chinese case-control studyLoss of the heparan sulfate sulfotransferase, Ndst1, in mammary epithelial cells selectively blocks lobuloalveolar development in miceMicroRNA-192 suppresses liver metastasis of colon cancer.The roles of TGFβ in the tumour microenvironment.TGF-beta biology in mammary development and breast cancer.Transforming growth factor beta (TGF-beta) and inflammation in cancer.Dihydrotestosterone potentiates EGF-induced ERK activation by inducing SRC in fetal lung fibroblastsAn integrated genomic approach identifies persistent tumor suppressive effects of transforming growth factor-β in human breast cancerCathepsin B is the driving force of esophageal cell invasion in a fibroblast-dependent manner.TGF-beta inactivation and TGF-alpha overexpression cooperate in an in vivo mouse model to induce hepatocellular carcinoma that recapitulates molecular features of human liver cancerAbcc10 status affects mammary tumour growth, metastasis, and docetaxel treatment responseThe E2F transcription factors regulate tumor development and metastasis in a mouse model of metastatic breast cancerAhnak functions as a tumor suppressor via modulation of TGFβ/Smad signaling pathway.Tgf-beta signaling pathway in lung adenocarcinoma invasion.MRC2 expression correlates with TGFβ1 and survival in hepatocellular carcinoma.Coordinated functions of E-cadherin and transforming growth factor beta receptor II in vitro and in vivo.Concerted loss of TGFβ-mediated proliferation control and E-cadherin disrupts epithelial homeostasis and causes oral squamous cell carcinoma.The Notch pathway inhibits TGFβ signaling in breast cancer through HEYL-mediated crosstalkMouse models of breast cancer metastasis.TGF-beta promotes cell death and suppresses lactation during the second stage of mammary involutionInhibition of TGF-beta with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression.Loss of transforming growth factor-beta type II receptor promotes metastatic head-and-neck squamous cell carcinoma.Transforming growth factor-beta regulator SnoN modulates mammary gland branching morphogenesis, postlactational involution, and mammary tumorigenesisLessons in signaling and tumorigenesis from polyomavirus middle T antigen.Wnt5a as an effector of TGFβ in mammary development and cancer
P2860
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P2860
Effect of conditional knockout of the type II TGF-beta receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasis
description
2005 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im März 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/03/15)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/03/15)
@nl
наукова стаття, опублікована в березні 2005
@uk
مقالة علمية (نشرت في 15-3-2005)
@ar
name
Effect of conditional knockout ...... tumor formation and metastasis
@ast
Effect of conditional knockout ...... tumor formation and metastasis
@en
Effect of conditional knockout ...... tumor formation and metastasis
@nl
type
label
Effect of conditional knockout ...... tumor formation and metastasis
@ast
Effect of conditional knockout ...... tumor formation and metastasis
@en
Effect of conditional knockout ...... tumor formation and metastasis
@nl
prefLabel
Effect of conditional knockout ...... tumor formation and metastasis
@ast
Effect of conditional knockout ...... tumor formation and metastasis
@en
Effect of conditional knockout ...... tumor formation and metastasis
@nl
P2093
P3181
P1433
P1476
Effect of conditional knockout ...... tumor formation and metastasis
@en
P2093
Agnieszka E. Gorska
Ali-Reza Sharif-Afshar
Anna Chytil
Elizabeth Forrester
Mary Aakre
William J. Muller
P304
P3181
P356
10.1158/0008-5472.CAN-04-3272
P407
P577
2005-03-15T00:00:00Z