Dietary salt regulates the phosphorylation of OSR1/SPAK kinases and the sodium chloride cotransporter through aldosterone
about
Molecular physiology of the thiazide-sensitive sodium-chloride cotransporterThe thiazide-sensitive Na+-Cl- cotransporter: molecular biology, functional properties, and regulation by WNKsAngiotensin II signaling increases activity of the renal Na-Cl cotransporter through a WNK4-SPAK-dependent pathwayWNK4 enhances the degradation of NCC through a sortilin-mediated lysosomal pathwayChronic over-nutrition and dysregulation of GSK3 in diseasesEpigenetic Modifications in Essential HypertensionAdenylyl cyclase 6 enhances NKCC2 expression and mediates vasopressin-induced phosphorylation of NKCC2 and NCCMechanism of salt-sensitive hypertension: focus on adrenal and sympathetic nervous systemsAcute insulin stimulation induces phosphorylation of the Na-Cl cotransporter in cultured distal mpkDCT cells and mouse kidney.Deletion of the angiotensin II type 1 receptor-associated protein enhances renal sodium reabsorption and exacerbates angiotensin II-mediated hypertensionRecent progress in histochemistry and cell biology.Regulation of with-no-lysine kinase signaling by Kelch-like proteins.Aldosterone acutely stimulates NCC activity via a SPAK-mediated pathway.WNK4 is the major WNK positively regulating NCC in the mouse kidneySPAK-knockout mice manifest Gitelman syndrome and impaired vasoconstriction.The WNKs: atypical protein kinases with pleiotropic actions.Distal convoluted tubuleγ-Adducin stimulates the thiazide-sensitive NaCl cotransporterGenetics of hypertension and cardiovascular disease and their interconnected pathways: lessons from large studies.Chemical library screening for WNK signalling inhibitors using fluorescence correlation spectroscopy.Paradoxical activation of the sodium chloride cotransporter (NCC) without hypertension in kidney deficient in a regulatory subunit of Na,K-ATPase, FXYD2.Impaired phosphorylation of Na(+)-K(+)-2Cl(-) cotransporter by oxidative stress-responsive kinase-1 deficiency manifests hypotension and Bartter-like syndromeSPAK-mediated NCC regulation in response to low-K+ dietAldosterone modulates thiazide-sensitive sodium chloride cotransporter abundance via DUSP6-mediated ERK1/2 signaling pathway.Hypertrophy in the Distal Convoluted Tubule of an 11β-Hydroxysteroid Dehydrogenase Type 2 Knockout Model.Discovery of Novel SPAK Inhibitors That Block WNK Kinase Signaling to Cation Chloride Transporters.Molecular physiology of SPAK and OSR1: two Ste20-related protein kinases regulating ion transport.WNK4 inhibits NCC protein expression through MAPK ERK1/2 signaling pathway.Activation of the renal Na+:Cl- cotransporter by angiotensin II is a WNK4-dependent process.Kelch-Like Protein 2 Mediates Angiotensin II-With No Lysine 3 Signaling in the Regulation of Vascular Tonus.Alternatively spliced proline-rich cassettes link WNK1 to aldosterone actionEffects of K+-deficient diets with and without NaCl supplementation on Na+, K+, and H2O transporters' abundance along the nephron.A new model of the distal convoluted tubule.SPAK isoforms and OSR1 regulate sodium-chloride co-transporters in a nephron-specific manner.A minor role of WNK3 in regulating phosphorylation of renal NKCC2 and NCC co-transporters in vivoChronic Metabolic Acidosis Activates Renal Tubular Sodium Chloride Cotransporter through Angiotension II-dependent WNK4-SPAK Phosphorylation Pathway.Osmotic stress induces the phosphorylation of WNK4 Ser575 via the p38MAPK-MK pathwayRegulation of the renal Na+-Cl- cotransporter by phosphorylation and ubiquitylation.Spironolactone ameliorates PIT1-dependent vascular osteoinduction in klotho-hypomorphic mice.Effects of ACE inhibition and ANG II stimulation on renal Na-Cl cotransporter distribution, phosphorylation, and membrane complex properties
P2860
Q24598213-DA39C8DA-B18B-4B83-BF6B-69443BA755DFQ24623288-F38390BC-CBAD-4E0A-BA97-9A0BBDF22291Q24648927-8F2132B3-5B1E-42CE-A8D0-A44FABA98A1AQ24652877-61FED608-4F95-44CB-9C65-0661ED4BD283Q26738964-4AA2258F-9EC4-4E05-A78F-FF7DD488E84AQ26749764-DCFDE77F-9856-4720-A9BF-CB2EDA674D4EQ28278647-2BA22E1B-1466-4EA4-9AE7-DEA5FE6C96C9Q33660709-3A19F5C7-1B60-446D-8436-44C9109FCE85Q34016466-266FB61E-9938-4F53-96C9-73627AACD1C4Q34111828-1CC4B691-F69A-453E-8387-040976A380E1Q34172616-9A68B4E1-998F-4362-BA90-9ABC54567DB9Q34174710-94E59025-0E16-4845-AE4B-3CAB2201122BQ34348908-B8B828F1-7D07-4854-AD62-3E275536D565Q34420520-539C83A2-A346-44D1-8047-ECAED4228355Q34457030-B1EBB737-883B-4B0C-AF4D-2EF5657ECB26Q34560188-DD1E35F7-DC66-4FDC-930C-149970E5E606Q34629804-3E8BFBF5-86F5-4814-AF4E-0B9F24620A06Q34695392-43710002-00DC-4FA3-A3F8-7D45504472E1Q34713661-A41D4D2F-B69F-42C5-B431-4FE8A3474CD1Q34974952-C0B68FAD-F139-4A0F-911D-375ECB3CB019Q35094158-08BDC45C-4F38-4B41-B1CD-F20CB92ADCE9Q35409776-92667B4E-DD04-468B-B7F1-8CBCE0EAAB19Q35436934-407C9D1E-7AE3-47F9-AA9A-D9125A5E6277Q35622471-FD6D4EBB-A28F-4151-85A0-C2D4B68465C1Q35790509-E9C8202A-D558-42AA-8818-09D7A7E695E5Q35790582-A98915F5-184B-4B57-B393-ED851FDC2E95Q35900778-0BAED599-B3C4-41B8-8CC4-4EAC97707479Q35964473-505EB613-8E57-4EA8-B978-9A9A88C5A81FQ35974133-D1672841-3EBC-4ADD-820B-152370CF7AA8Q36003108-00B7C449-06B2-47DF-AF23-147163687D3EQ36106011-79770139-E1BC-4FB6-8749-9C26E77A4F5CQ36200312-B065415D-1035-4634-A01E-C19FE70CF493Q36309374-E74EB2D4-D1E9-4E7C-B009-061FE9D51669Q36368185-32C31082-E102-4BE7-AF05-8BC6B31C7E36Q36425591-6D564E3A-784C-4E8B-8DF2-B6022589F98DQ36427915-CE4C0B23-AB40-4297-A617-9726EF57F431Q36432448-F09403FF-9DF5-4AF9-BC83-A323000E693AQ36494423-7FBF3F09-20C2-46EF-B8DF-9E92DF35C757Q36580372-8B0633E7-72F9-454B-BFD6-95C5A72C6FE2Q36654263-B6FB73D3-8BA7-4F14-8C33-F3A5EC7492BD
P2860
Dietary salt regulates the phosphorylation of OSR1/SPAK kinases and the sodium chloride cotransporter through aldosterone
description
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im Dezember 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/12/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/12/01)
@nl
наукова стаття, опублікована в грудні 2008
@uk
مقالة علمية (نشرت في ديسمبر 2008)
@ar
name
Dietary salt regulates the pho ...... ransporter through aldosterone
@ast
Dietary salt regulates the pho ...... ransporter through aldosterone
@en
Dietary salt regulates the pho ...... ransporter through aldosterone
@nl
type
label
Dietary salt regulates the pho ...... ransporter through aldosterone
@ast
Dietary salt regulates the pho ...... ransporter through aldosterone
@en
Dietary salt regulates the pho ...... ransporter through aldosterone
@nl
prefLabel
Dietary salt regulates the pho ...... ransporter through aldosterone
@ast
Dietary salt regulates the pho ...... ransporter through aldosterone
@en
Dietary salt regulates the pho ...... ransporter through aldosterone
@nl
P2093
P3181
P356
P1433
P1476
Dietary salt regulates the pho ...... ransporter through aldosterone
@en
P2093
Akihito Ohta
Motoko Chiga
Sei Sasaki
Shinichi Uchida
Sung-Sen Yang
Tatemitsu Rai
Toichiro Takizawa
P2888
P304
P3181
P356
10.1038/KI.2008.451
P407
P577
2008-12-01T00:00:00Z
P5875
P6179
1010450770