An inherited limb deformity created by insertional mutagenesis in a transgenic mouse
about
FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligandsFormin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domainsWW domain-mediated interactions reveal a spliceosome-associated protein that binds a third class of proline-rich motif: the proline glycine and methionine-rich motifThe formin/diaphanous-related protein, FHOS, interacts with Rac1 and activates transcription from the serum response elementGenetic evidence that formins function within the nucleusDeficient outgrowth of the ureteric bud underlies the renal agenesis phenotype in mice manifesting the limb deformity (ld) mutationIdentification of morc (microrchidia), a mutation that results in arrest of spermatogenesis at an early meiotic stage in the mouseThe role of a single formin isoform in the limb and renal phenotypes of limb deformityMouse limb deformity mutations disrupt a global control region within the large regulatory landscape required for Gremlin expressionA new mouse insertional mutation that causes sensorineural deafness and vestibular defectsPrenatal lethality in a transgenic mouse line is the result of a chromosomal translocationDifferential plasmid rescue from transgenic mouse DNAs into Escherichia coli methylation-restriction mutantsHomologous illegitimate random integration of foreign DNA into the X chromosome of a transgenic mouse line.Insertional mutation in a transgenic mouse allelic with Purkinje cell degeneration.Sequential expression of murine homeo box genes during F9 EC cell differentiationGenomic identification of regulatory elements by evolutionary sequence comparison and functional analysisTransgene-induced mutation of the murine steel locusGenetic background affects integration frequency of ecotropic proviral sequences into the mouse germ line.Molecular and phenotypic characterization of a new mouse insertional mutation that causes a defect in the distal vertebrae of the spine.Use of genetically engineered mice in drug discovery and development: wielding Occam's razor to prune the product portfolio.Activation of retrovirus in transgenic mice: association with development of olfactory neuroblastoma.Molecular analysis of heritable mouse mutations.Tandemly repeated transgenes of the human minisatellite MS32 (D1S8), with novel mouse gamma satellite integrationA human gene homologous to the formin gene residing at the murine limb deformity locus: chromosomal location and RFLPsPhysiological genetics--who needs it?Animal models of human disease. Pathology and molecular biology of spontaneous neoplasms occurring in transgenic mice carrying and expressing activated cellular oncogenes.Developing genetically engineered mouse models to study tumor suppression.Rhabdomyosarcoma arising in transgenic mice harboring the beta-globin locus control region fused with simian virus 40 large T antigen gene.Real-time quantitative PCR for the design of lentiviral vector analytical assays.Formins: phosphoprotein isoforms encoded by the mouse limb deformity locus.The mouse formin (Fmn) gene: abundant circular RNA transcripts and gene-targeted deletion analysis.The molecular and genetic analysis of mouse development.Structure, expression, and chromosome location of the gene for the beta subunit of brain-specific Ca2+/calmodulin-dependent protein kinase II identified by transgene integration in an embryonic lethal mouse mutant.Analysis of the integrant in MyK-103 transgenic mice in which males fail to transmit the integrant.Cellular DNA rearrangements and early developmental arrest caused by DNA insertion in transgenic mouse embryos.A foreign dihydrofolate reductase gene in transgenic mice acts as a dominant mutationTissue-specific and developmentally regulated expression of a chimeric actin-globin gene in transgenic mice.The mutant axolotl Short toes exhibits impaired limb regeneration and abnormal basement membrane formationFormins: emerging players in the dynamic plant cell cortexEarly postimplantation embryo lethality due to DNA rearrangements in a transgenic mouse strain.
P2860
Q24532189-390E85A6-79DD-4A20-BE5E-76B1307A090BQ24563234-31DB358C-CE42-4560-BEBD-F8A0CB2C97E3Q24657609-D16C2B61-BEBC-4378-90DA-0CFE4514B8EFQ28190692-2C18E138-EC4E-42C3-B830-4C6A8E70AD74Q28506903-661AFCF9-27A5-4EEA-A93B-3C185369A457Q28513203-813DA35A-1ECC-4642-9CBF-DB9FFEC1E93FQ28513262-EE5AE7BE-C7F5-40EA-B5F8-B15618E8E0F2Q28513458-E32BD62F-E585-4F72-9019-E54671C9BE5CQ28588797-671312DA-3689-422F-B03B-F02DDCDDCE6FQ28591820-8BAF1617-AC96-4D1E-BAF8-3DEDEEBFB4D0Q33553804-3563B8FA-B4F3-4AD9-9485-AB38BEFA60FBQ33637017-F7144E98-0DA6-408A-AE5C-90C013FA1A71Q33657388-20E7DDD7-22BF-4063-BA54-698DA359DA27Q33857716-88911910-96A7-4FA8-8298-A165445EE499Q33880331-9489C915-5066-49BE-9246-D32CF3986A70Q33899702-832B097C-6287-4EA7-A6BE-87A944B5D0F7Q33927926-3F8BEC51-78A8-4FDA-B617-75D0617D800AQ33928899-0B5E4F98-C74A-453C-82DD-2D12004AAA55Q33965422-0CECD225-982D-42FD-9ADC-0B8C8CEC879FQ34590536-4D2EEBD9-DCEA-4CBF-BB57-D04F12BC69A2Q34629913-85275D96-D127-43E0-9E3A-BFBC0E83568CQ34660322-DF584296-421A-4B3E-8218-081A199121A6Q35009180-428EE3E3-49B2-42FB-AF6A-47F333155892Q35196383-BC823329-1D11-47F8-B891-AE0E1DC1BF92Q35198969-AAF91588-1F8E-45F8-89B3-C61287B51A73Q35817599-A27DA1D3-2A06-4751-B6D7-5EF64215F34FQ35949604-2528FE6A-1EA8-4ADE-98DC-1C559133108BQ36206322-CDD4E8BC-A464-440B-A372-248E3E2711F6Q36288916-F227148D-150D-4FB3-B362-4E4CC0C52406Q36363617-07060547-53E0-4B71-93E7-91B7C49DBF49Q36438235-94E975BF-63CD-401B-B333-E1C43FAAF6F4Q36777403-1271E63F-92F4-44F4-A76D-95D238903BC9Q36822134-08E13DB1-9D58-4CCB-8678-BBD140FC3628Q36839770-DC0C7BF2-4286-4FFE-AFD4-C069A37F3310Q36842552-DC885965-D7C8-457D-B72B-5E04351E339FQ36915856-00BADB24-B7BA-4AD0-9F34-01F9AB10B43CQ36917639-5714B676-ADF4-4D01-828E-F68391A96070Q37062843-A3297FD2-3443-4856-BE30-EDACFEC961E9Q37288553-DA88CEFF-BC30-4962-8D88-8086CD545A70Q37395024-E94DC08B-16D6-41C5-A9F5-17DE1974F425
P2860
An inherited limb deformity created by insertional mutagenesis in a transgenic mouse
description
2016 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Nature
@fr
artículu científicu espublizáu en 2016
@ast
scientific journal article
@en
vedecký článok (publikovaný 2016/11/07)
@sk
vědecký článek publikovaný v roce 2016
@cs
wetenschappelijk artikel (gepubliceerd op 2016/11/07)
@nl
наукова стаття, опублікована в листопаді 2016
@uk
مقالة علمية (نشرت في 7-11-2016)
@ar
name
An inherited limb deformity created by insertional mutagenesis in a transgenic mouse
@ast
An inherited limb deformity created by insertional mutagenesis in a transgenic mouse
@en
An inherited limb deformity created by insertional mutagenesis in a transgenic mouse
@nl
type
label
An inherited limb deformity created by insertional mutagenesis in a transgenic mouse
@ast
An inherited limb deformity created by insertional mutagenesis in a transgenic mouse
@en
An inherited limb deformity created by insertional mutagenesis in a transgenic mouse
@nl
prefLabel
An inherited limb deformity created by insertional mutagenesis in a transgenic mouse
@ast
An inherited limb deformity created by insertional mutagenesis in a transgenic mouse
@en
An inherited limb deformity created by insertional mutagenesis in a transgenic mouse
@nl
P2093
P356
P1433
P1476
An inherited limb deformity created by insertional mutagenesis in a transgenic mouse
@en
P2093
L. G. Davis
R. P. Woychik
T. A. Stewart
P2888
P356
10.1038/318036A0
P407
P577
2016-11-07T00:00:00Z
P6179
1015690379