Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosis
about
Lack of Cul4b, an E3 ubiquitin ligase component, leads to embryonic lethality and abnormal placental development.The epigenetic regulator CXXC finger protein 1 is essential for murine hematopoiesis.Cul4A is an oncogene in malignant pleural mesothelioma.Knockdown of cullin 4A inhibits growth and increases chemosensitivity in lung cancer cellsProliferation defects and genome instability in cells lacking Cul4A.Characterization of nuclear localization signal in the N terminus of CUL4B and its essential role in cyclin E degradation and cell cycle progression.Advances in mobilization for the optimization of autologous stem cell transplantation.Cullin 4A is associated with epithelial to mesenchymal transition and poor prognosis in perihilar cholangiocarcinoma.Implications of endoplasmic reticulum stress, the unfolded protein response and apoptosis for molecular cancer therapy. Part II: targeting cell cycle events, caspases, NF-κB and the proteasome.CUL4A is overexpressed in human pituitary adenomas and regulates pituitary tumor cell proliferation.Knockdown of CUL4A inhibits invasion and induces apoptosis in osteosarcoma cells.Identification of new loci involved in the host susceptibility to Salmonella Typhimurium in collaborative cross mice.
P2860
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P2860
Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosis
description
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
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im Juli 2008 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2008/07/15)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/07/15)
@nl
наукова стаття, опублікована в липні 2008
@uk
مقالة علمية (نشرت في 15-7-2008)
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name
Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosis
@ast
Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosis
@en
Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosis
@nl
type
label
Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosis
@ast
Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosis
@en
Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosis
@nl
prefLabel
Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosis
@ast
Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosis
@en
Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosis
@nl
P2093
P2860
P1433
P1476
Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosis
@en
P2093
Binghui Li
David L. Waning
Harm HogenEsch
Kristin T. Chun
W. Scott Goebel
Yahaira Naaldijk
P2860
P304
P356
10.1182/BLOOD-2007-11-126300
P407
P577
2008-07-15T00:00:00Z