The homeobox gene Hesx1 is required in the anterior neural ectoderm for normal forebrain formation
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Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesisA role of the LIM-homeobox gene Lhx2 in the regulation of pituitary developmentDNMT1 interacts with the developmental transcriptional repressor HESX1Six3 repression of Wnt signaling in the anterior neuroectoderm is essential for vertebrate forebrain developmentA homozygous mutation in HESX1 is associated with evolving hypopituitarism due to impaired repressor-corepressor interactionWnt signaling is regulated by endoplasmic reticulum retentionGenetic interaction between the homeobox transcription factors HESX1 and SIX3 is required for normal pituitary developmentCorrect patterning of the primitive streak requires the anterior visceral endodermCombined pituitary hormone deficiency: current and future status.Genetic regulation of pituitary gland development in human and mouseExpression of pluripotency master regulators during two key developmental transitions: EGA and early lineage specification in the bovine embryo.Morphogenetic tissue movement and the establishment of body plan during development from blastocyst to gastrula in the mouse.Septo-optic dysplasiaMissense mutations of human homeoboxes: A review.HESX1- and TCF3-mediated repression of Wnt/β-catenin targets is required for normal development of the anterior forebrain.Clonal and molecular analysis of the prospective anterior neural boundary in the mouse embryo.The hypoblast (visceral endoderm): an evo-devo perspective.Dkk1 and noggin cooperate in mammalian head induction.Hhex is Required at Multiple Stages of Adult Hematopoietic Stem and Progenitor Cell Differentiation.Unique spatiotemporal requirements for intraflagellar transport genes during forebrain development.Lack of the murine homeobox gene Hesx1 leads to a posterior transformation of the anterior forebrainMolecular physiology of pituitary development: signaling and transcriptional networks.Cornelia de Lange Syndrome: NIPBL haploinsufficiency downregulates canonical Wnt pathway in zebrafish embryos and patients fibroblasts.Confirmation of RAX gene involvement in human anophthalmia.Characterization of a novel HESX1 mutation in a pediatric case of septo-optic dysplasia.Ontogenesis of hepatic and pancreatic stem cells.Developmental mechanisms directing early anterior forebrain specification in vertebratesEmergence of neuronal diversity from patterning of telencephalic progenitors.Genetics of Combined Pituitary Hormone Deficiency: Roadmap into the Genome Era.Dkk1-dependent inhibition of Wnt signaling activates Hesx1 expression through its 5' enhancer and directs forebrain precursor development.The tumor suppressor HHEX inhibits axon growth when prematurely expressed in developing central nervous system neurons.Adenovirus-mediated increase of HNF-3 levels stimulates expression of transthyretin and sonic hedgehog, which is associated with F9 cell differentiation toward the visceral endoderm lineage.FGF dependent regulation of Zfhx1b gene expression promotes the formation of definitive neural stem cells in the mouse anterior neurectoderm.Time-Course Gene Expression Profiling Reveals a Novel Role of Non-Canonical WNT Signaling During Neural Induction.Analysis of mouse models carrying the I26T and R160C substitutions in the transcriptional repressor HESX1 as models for septo-optic dysplasia and hypopituitarism.HESX1 mutations in patients with congenital hypopituitarism: variable phenotypes with the same genotype.Stage-dependent plasticity of the anterior neural folds to form neural crest.Heterozygous mutation of HESX1 causing hypopituitarism and multiple anatomical malformations without features of septo-optic dysplasia.
P2860
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P2860
The homeobox gene Hesx1 is required in the anterior neural ectoderm for normal forebrain formation
description
2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2000
@ast
im Juli 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/07/15)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/07/15)
@nl
наукова стаття, опублікована в липні 2000
@uk
مقالة علمية نشرت في 15-7-2000 حول موضوع: دماغ
@ar
name
The homeobox gene Hesx1 is req ...... for normal forebrain formation
@ast
The homeobox gene Hesx1 is req ...... for normal forebrain formation
@en
The homeobox gene Hesx1 is req ...... for normal forebrain formation
@nl
type
label
The homeobox gene Hesx1 is req ...... for normal forebrain formation
@ast
The homeobox gene Hesx1 is req ...... for normal forebrain formation
@en
The homeobox gene Hesx1 is req ...... for normal forebrain formation
@nl
prefLabel
The homeobox gene Hesx1 is req ...... for normal forebrain formation
@ast
The homeobox gene Hesx1 is req ...... for normal forebrain formation
@en
The homeobox gene Hesx1 is req ...... for normal forebrain formation
@nl
P2093
P3181
P356
P1476
The homeobox gene Hesx1 is req ...... for normal forebrain formation
@en
P2093
J. P. Martinez-Barbera
R. S. Beddington
T. A. Rodriguez
P304
P3181
P356
10.1006/DBIO.2000.9757
P407
P577
2000-07-15T00:00:00Z