Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesis
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Disruption of parallel and converging signaling pathways contributes to the synergistic antitumor effects of simultaneous mTOR and EGFR inhibition in GBM cellsProfile of panitumumab as first-line treatment in patients with wild-type KRAS metastatic colorectal cancerEGFR/Ras Signaling Controls Drosophila Intestinal Stem Cell Proliferation via Capicua-Regulated GenesEffect of Sulindac and Erlotinib vs Placebo on Duodenal Neoplasia in Familial Adenomatous Polyposis: A Randomized Clinical Trial.Insulin receptor substrate-1 deficiency promotes apoptosis in the putative intestinal crypt stem cell region, limits Apcmin/+ tumors, and regulates Sox9Betacellulin stimulates growth of the mouse intestinal epithelium and increases adenoma multiplicity in Apc+/Min miceAlpha-catenin is essential in intestinal adenoma formationPrognostic effect of activated EGFR expression in human colon carcinomas: comparison with EGFR statusMurine models of colorectal cancer.Mutant EGFR is required for maintenance of glioma growth in vivo, and its ablation leads to escape from receptor dependence.Diacylglycerol kinase delta and protein kinase C(alpha) modulate epidermal growth factor receptor abundance and degradation through ubiquitin-specific protease 8.Role for the epidermal growth factor receptor in neurofibromatosis-related peripheral nerve tumorigenesis.Suppressor of cytokine signaling-2 gene disruption promotes Apc(Min/+) tumorigenesis and activator protein-1 activationInducible loss of one Apc allele in Lrig1-expressing progenitor cells results in multiple distal colonic tumors with features of familial adenomatous polyposis.Dual inhibition of epidermal growth factor and insulin-like 1 growth factor receptors reduce intestinal adenoma burden in the Apc(min/+) mouse.Intestinal adenomas can develop with a stable karyotype and stable microsatellitesConvergence between Wnt-β-catenin and EGFR signaling in cancer.Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling.Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signalingA comprehensive continuous-time model for the appearance of CGH signal due to chromosomal missegregations during mitosis.Efficacy of EGFR inhibition is modulated by model, sex, genetic background and diet: implications for preclinical cancer prevention and therapy trialsAlteration of EGFR spatiotemporal dynamics suppresses signal transduction.Chemopreventive effects of berberine on intestinal tumor development in Apcmin/+ miceBerberine inhibits proliferation and down-regulates epidermal growth factor receptor through activation of Cbl in colon tumor cells.Muscarinic receptor agonists stimulate human colon cancer cell migration and invasion.Perinatal epidermal growth factor receptor blockade prevents peripheral nerve disruption in a mouse model reminiscent of benign world health organization grade I neurofibromaThe role of receptor tyrosine kinase inhibition in treating gastrointestinal malignancy.A phase IIa randomized, double-blind trial of erlotinib in inhibiting epidermal growth factor receptor signaling in aberrant crypt foci of the colorectumMuscarinic receptor subtype-3 gene ablation and scopolamine butylbromide treatment attenuate small intestinal neoplasia in Apcmin/+ mice.The role of COX-2 in intestinal inflammation and colorectal cancerGenetic variability in EGFR, Src and HER2 and risk of colorectal adenoma and cancer.Luteinizing hormone-dependent activation of the epidermal growth factor network is essential for ovulationAspirin Prevents Colorectal Cancer by Normalizing EGFR Expression.Matrix metalloproteinase-7-catalyzed release of HB-EGF mediates deoxycholyltaurine-induced proliferation of a human colon cancer cell line.Insulin-like growth factor 1 activates methionine adenosyltransferase 2A transcription by multiple pathways in human colon cancer cells.The neurotensin receptor-1 promotes tumor development in a sporadic but not an inflammation-associated mouse model of colon cancer.Dietary calcium supplementation enhances efficacy but also toxicity of EGFR inhibitor therapy for colon cancer.Reconstruction of explicit structural properties at the nanoscale via spectroscopic microscopy.Review article: the potential of combinational regimen with non-steroidal anti-inflammatory drugs in the chemoprevention of colorectal cancer.Epidermal growth factor receptor inhibits colitis-associated cancer in mice
P2860
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P2860
Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesis
description
2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2002
@ast
im Februar 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/02/05)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/02/05)
@nl
наукова стаття, опублікована в лютому 2002
@uk
name
Importance of epidermal growth ...... uring intestinal tumorigenesis
@ast
Importance of epidermal growth ...... uring intestinal tumorigenesis
@en
Importance of epidermal growth ...... uring intestinal tumorigenesis
@nl
type
label
Importance of epidermal growth ...... uring intestinal tumorigenesis
@ast
Importance of epidermal growth ...... uring intestinal tumorigenesis
@en
Importance of epidermal growth ...... uring intestinal tumorigenesis
@nl
prefLabel
Importance of epidermal growth ...... uring intestinal tumorigenesis
@ast
Importance of epidermal growth ...... uring intestinal tumorigenesis
@en
Importance of epidermal growth ...... uring intestinal tumorigenesis
@nl
P2093
P2860
P356
P1476
Importance of epidermal growth ...... uring intestinal tumorigenesis
@en
P2093
David W. Threadgill
M. Kay Washington
Reade B. Roberts
Robert J. Coffey
Sandra J. Olsen
Stephen H. Settle
P2860
P304
P356
10.1073/PNAS.032678499
P407
P577
2002-02-05T00:00:00Z