Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells
about
Systematic approaches to identify E3 ligase substratesDownregulation of the proapoptotic protein MOAP-1 by the UBR5 ubiquitin ligase and its role in ovarian cancer resistance to cisplatinDUBA-UBR5 axis: other than transactivation.Identification of new susceptibility loci for IgA nephropathy in Han Chinese.The MLLE domain of the ubiquitin ligase UBR5 binds to its catalytic domain to regulate substrate binding.TRAF5-mediated Lys-63-linked Polyubiquitination Plays an Essential Role in Positive Regulation of RORγt in Promoting IL-17A ExpressionRetinoic Acid-Related Orphan Receptors (RORs): Regulatory Functions in Immunity, Development, Circadian Rhythm, and Metabolism.USP16 Downregulation by Carboxyl-terminal Truncated HBx Promotes the Growth of Hepatocellular Carcinoma CellsBMI1-UBR5 axis regulates transcriptional repression at damaged chromatin.Ubiquitin Ligases and Deubiquitinating Enzymes in CD4+ T Cell Effector Fate Choice and Function.The increasing complexity of the ubiquitin code.Therapeutic Potential of Targeting the Th17/Treg Axis in Autoimmune Disorders.The transcriptional repressor HIC1 regulates intestinal immune homeostasis.Ubiquitination of RORγt at Lysine 446 Limits Th17 Differentiation by Controlling Coactivator Recruitment.What Genetics Tells Us About the Pathogenesis of IgA Nephropathy: The Role of Immune Factors and Infection.The Itch to degrade ROR-γt.The de-ubiquitylating enzyme DUBA is essential for spermatogenesis in Drosophila.Establishment of S100A8 Transgenic Rats to Understand Innate Property of S100A8 and Its Immunological Role.miRNA-23a/CXCR4 regulates neuropathic pain via directly targeting TXNIP/NLRP3 inflammasome axis.Structural studies unravel the active conformation of apo RORγt nuclear receptor and a common inverse agonism of two diverse classes of RORγt inhibitors.Itch inhibits IL-17-mediated colon inflammation and tumorigenesis by ROR-γt ubiquitination.The p90 ribosomal S6 kinase-UBR5 pathway controls Toll-like receptor signaling via miRNA-induced translational inhibition of tumor necrosis factor receptor-associated factor 3.The role of TGF-β in Th17 differentiation.Bach2 repression mediates Th17 cell induced inflammation and associates with clinical features of advanced disease in chronic pancreatitis.SUMOylation of ROR-γt inhibits IL-17 expression and inflammation via HDAC2Sumoylation of RORγt regulates T17 differentiation and thymocyte development
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P2860
Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells
description
2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Nature
@fr
artículu científicu espublizáu en 2015
@ast
scientific journal article
@en
vedecký článok (publikovaný 2015/02/19)
@sk
vědecký článek publikovaný v roce 2015
@cs
wetenschappelijk artikel (gepubliceerd op 2015/02/19)
@nl
наукова стаття, опублікована в лютому 2015
@uk
مقالة علمية (نشرت في 19-2-2015)
@ar
name
Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells
@ast
Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells
@en
Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells
@nl
type
label
Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells
@ast
Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells
@en
Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells
@nl
prefLabel
Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells
@ast
Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells
@en
Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells
@nl
P2093
P2860
P50
P921
P3181
P356
P1433
P1476
Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells
@en
P2093
Benjamin P. Fauber
Donald S. Kirkpatrick
Jennie R. Lill
Joshua Webster
Kim Newton
Mark Vasser
Nobuhiko Kayagaki
Oscar W. Huang
Qui T. Phung
Rajkumar Noubade
P2860
P2888
P304
P3181
P356
10.1038/NATURE13979
P407
P577
2015-02-19T00:00:00Z
P6179
1044132762